Ahmed Bakeer¹, Grigory Kazakevich², Viktoriia Podryga^3,*, Yury Poveshchenko³, Parvin Rahimly³

Frontiers in Heat and Mass Transfer, Vol.23, No.5, pp. 1575-1593, 2025, DOI:10.32604/fhmt.2025.067097 - 31 October 2025

Abstract The work considers the problem of gas hydrate dissociation in a porous medium using the two-term Forchheimer law, corresponding to high flow rates of reservoir fluids. Such rates can arise during the decomposition of gas hydrates, since a large amount of gas is released. Intensive emissions of gases from the earth’s interior are observed on the ocean floor. They are also associated with a large number of subvertical geological structures under the ocean floor, coming to the surface in the form of local ring funnels (pockmarks). Many similar objects have also been found on land.… More >

Yuhang Liu¹, Xiaoying Zhuang^1,2,*, Huilong Ren¹

CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.3, pp. 3287-3305, 2025, DOI:10.32604/cmes.2025.070018 - 30 September 2025

Abstract Shallow-buried thick sand strata present considerable local instability risks during diaphragm wall trenching construction. However, this critical issue has not been extensively studied, despite its serious safety consequences. This paper proposes an automatic identification model for shallow-buried thick sand strata, integrating three-dimensional limit equilibrium theory with a genetic algorithm to precisely identify the most potentially dangerous local instability mass and determine its minimum safety factor. The model establishes three undetermined parameters: failure angle, upper boundary, and thickness of the local instability mass. These parameters define the search space for the local instability mass. The effectiveness… More >

Hailong Li^1,#, Wen Ouyang^2,#, Yiyin Long¹, Yun Peng¹, Ziyi Liu¹, Qi Zhou¹, Rong Xu^1,*, Wei Du^1,*

Oncology Research, Vol.33, No.9, pp. 2549-2571, 2025, DOI:10.32604/or.2025.065050 - 28 August 2025

Abstract Background: The study aimed to explore the clinical value of mitochondrial ribosomal protein L18 (MRPL18) in breast cancer. Methods: Multiple databases were used to validate the expression of MRPL18. The prognostic impact and predictive value of MRPL18 were evaluated by using predictive models. Protein-protein interaction (PPI) networks were constructed by using GeneMANIA. Enrichment analysis is used to explore the signaling pathway regulated by MRPL18. Cell counting kit-8 (CCK-8) assays, colony formation, migration assays, flow cytometry, and xenograft models were employed to evaluate the role of MRPL18 in tumor progression. The immune response of MRPL18 was More >

Flávia Naves Ferreira do Prado¹, Michelle Garcia Gomes¹, Marcela Piassi Bernardo¹, Daniel Pasquini^1,*, Anízio Márcio de Faria², Luís Carlos de Morais^3,*

Journal of Renewable Materials, Vol.13, No.5, pp. 957-980, 2025, DOI:10.32604/jrm.2025.02024-0014 - 20 May 2025

Abstract Alternative methods for biodiesel purification that focus on ease of operation, cost reduction, and elimination of contaminated residues or that are easier to treat have received more attention. The dry wash route was used as an alternative to the wet route in biodiesel production. Filter membranes were developed based on cellulose nanofibers as the matrix and sugarcane bagasse fibers or soy hulls, as reinforcement to the matrix, before and after two chemical treatments (carboxymethylation and regeneration with sulfuric acid). The filters were characterized by permeability capacity, morphology, wettability, porosity, SEM and mechanical properties. The filtered… More > Graphic Abstract

Hongjuan Guo¹, Dan Liu^1,2, Ruyu Yan^1,2, Tianjing Zhang³, Kecheng Zhou^1,2,*, Minxia Liu^1,*

BIOCELL, Vol.49, No.3, pp. 483-502, 2025, DOI:10.32604/biocell.2025.062143 - 31 March 2025

Abstract Objectives: Non-small cell lung cancer (NSCLC) represents a formidable malignancy characterized by its marked metastatic potential and intrinsic resistance to therapeutic interventions. The identification of potential biomarkers delineating the progression and metastatic cascade of NSCLC assumes paramount importance in fostering advancements toward enhanced patient outcomes and prognostic stratification. Methods: The expression level of the actin-related protein 2/3 complex; subunit 1A (ARPC1A) in NSCLC was evaluated using The Cancer Genome Atlas (TCGA) and Gene Expression Profiling Interactive Analysis (GEPIA) databases; along with the LinkedOmics database for co-expression genes. Further verification of ARPC1A expression in normal lung cells… More >

LI SUN^1,#, SHICHAO ZHUO^2,#, XIAOXIN LI², HUSHENG KONG³, WEIWEI DU³, CHONG ZHOU⁴, JUNXING HUANG^1,*

Oncology Research, Vol.33, No.3, pp. 641-651, 2025, DOI:10.32604/or.2024.050057 - 28 February 2025

Abstract Background: Cisplatin (DDP) has been used in the treatment of various human cancers. However, DDP alone lacks efficacy in treating triple-negative breast cancer (TNBC), and its clinical application is often hampered by side effects. Astragalus polysaccharide (APS) is one of the active components extracted from Astragalus membranaceus and has gained attention for its various biological properties. This research is aimed to evaluate the effectiveness of a combination of APS and DDP on TNBC and explore the potential mechanisms. Methods: The efficacy and mechanisms of single or combined treatment were evaluated using Cell Counting Kit-8 (CCK8) assay, Annexin… More >

Abiodun Abdulhameed Amusa^1,*, Anwar Johari¹, Kamil Kayode Katibi^2,3, Ibrahim Garba Shitu^4,5, Abdulrahman Oyekanmi Adeleke⁶, Mohd Fairus Mohd Yasin⁷, Muhammad Thalhah Zainal⁸

Journal of Renewable Materials, Vol.13, No.2, pp. 251-272, 2025, DOI:10.32604/jrm.2025.057487 - 20 February 2025

Abstract The increasing severity of air pollution necessitates more effective and sustained air filtration technology. Concurrently, the desire for more environmentally friendly, sustainable materials with better filtering performance and less environmental impact drives the move away from conventional synthetic membranes. This review presents lignocellulosic biocomposite (LigBioComp) membranes as an alternative to traditional synthetic membranes. It focuses on their materials, fabrication, and functionalization techniques while exploring challenges and proposing methods for resourceful utilization. Renowned for their abundance and renewable nature, lignocellulosic materials consist of cellulose, hemicellulose, and lignin. Various applications can benefit from their antibacterial properties,… More > Graphic Abstract

Yanina N. Parshakova^*, Andrey Ivantsov

FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.12, pp. 2709-2720, 2024, DOI:10.32604/fdmp.2024.052396 - 23 December 2024

Abstract During the manufacturing or processing of materials, large volumes of water of the required quality are often needed. Industrial water treatment and water purification is the process of removing impurities and pollution from the considered medium. To obtain liquid with specified quality parameters, complex systems of filters and treatment facilities are generally used. In this work, the cleaning process for a filtration column is studied. Three-dimensional numerical simulations of flow in a columnar array consisting of a porous medium are conducted. In particular, a model case corresponding to laboratory conditions is examined, with potassium salt… More >

Han Wang^1,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.3, pp. 1-1, 2024, DOI:10.32604/icces.2024.012843

Abstract Aluminum lattice structures have the advantages of lightweight, high specific strength/stiffness and excellent plasticity, while alumina ceramic lattice structures usually show high strength and significant brittleness. Therefore, alumina/aluminum interpenetrating composites can combine two distinct mechanical properties and show superior performance, which is beneficial to applications in aerospace and military industries. In this study, alumina ceramic lattice structures were prepared by additive manufacturing (AM) and used as infiltration skeleton. The molten aluminum was then infiltrated into alumina ceramic lattice structures. By this method, the alumina/aluminum ordered structure composites were prepared. Through mechanical experiments and finite element More >

Guizhou Liu^1,2, Chunze Yan^1,2,*, Yusheng Shi^1,2

The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.4, pp. 1-1, 2024, DOI:10.32604/icces.2024.013340

Abstract High-volume-fraction SiC/Al (HVF-SiC/Al) have a wide range of applications in aerospace, optics, automotive and electronic packaging. However, because the hardness, brittleness and wear resistance increase with the increase in the volume fraction, it is difficult for traditional methods such as machining, to process HVF-SiC/Al composites to complex components. Therefore, in this paper, a novel method of the hybrid additive manufacturing is proposed to fabricate HVF-SiC/Al parts with complex structures. The effect of polymer infiltration and pyrolysis (PIP) on microstructure and properties of HVF-SiC/Al composites is investigated. The results show that the mechanical properties of the… More >