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  • Open Access

    ARTICLE

    Influence of Arterial Wall Compliance on the Pressure Drop across Coronary Artery Stenoses under Hyperemic Flow Condition

    Bhaskar Chandra Konala, Ashish Das, Rupak K Banerjee∗,†

    Molecular & Cellular Biomechanics, Vol.8, No.1, pp. 1-20, 2011, DOI:10.3970/mcb.2011.008.001

    Abstract Hemodynamic endpoints such as flow and pressure drop are often measured during angioplasty procedures to determine the functional severity of a coronary artery stenosis. There is a lack of knowledge regarding the influence of compliance of the arterial wall-stenosis on the pressure drop under hyperemic flows across coronary lesions. This study evaluates the influence in flow and pressure drop caused by variation in arterial-stenosis compliance for a wide range of stenosis severities. The flow and pressure drop were evaluated for three different severities of stenosis and tested for limiting scenarios of compliant models. The Mooney-Rivlin… More >

  • Open Access

    ARTICLE

    Calculation of a Deformable Membrane Airfoil in Hovering Flight

    D.M.S. Albuquerque1, J.M.C. Pereira1, J.C.F. Pereira1,2

    CMES-Computer Modeling in Engineering & Sciences, Vol.72, No.4, pp. 337-366, 2011, DOI:10.3970/cmes.2011.072.337

    Abstract A numerical study of fluid-structure interaction is presented for the analysis of viscous flow over a resonant membrane airfoil in hovering flight. A flexible membrane moving with a prescribed stroke period was naturally excited to enter into 1st, 2nd and 3rd mode of vibration according to the selected membrane tension. The Navier-Stokes equations were discretized on a moving body unstructured grid using the finite volume method. The instantaneous membrane position was predicted by the 1D unsteady membrane equation with input from the acting fluid flow forces. Following initial validation against reported rigid airfoils predictions, the… More >

  • Open Access

    ARTICLE

    Patient-Specific Carotid Plaque Progression Simulation Using 3D Meshless Generalized Finite Difference Models with Fluid-Structure Interactions Based on Serial In Vivo MRI Data

    Chun Yang1,2, Dalin Tang2, Satya Atluri3

    CMES-Computer Modeling in Engineering & Sciences, Vol.72, No.1, pp. 53-78, 2011, DOI:10.3970/cmes.2011.072.053

    Abstract Previously, we introduced a computational procedure based on three-dimensional meshless generalized finite difference (MGFD) method and serial magnetic resonance imaging (MRI) data to quantify patient-specific carotid atherosclerotic plaque growth functions and simulate plaque progression. Structure-only models were used in our previous report. In this paper, fluid-stricture interaction (FSI) was added to improve on prediction accuracy. One participating patient was scanned three times (T1, T2, and T3, at intervals of about 18 months) to obtain plaque progression data. Blood flow was assumed to laminar, Newtonian, viscous and incompressible. The Navier-Stokes equations with arbitrary Lagrangian-Eulerian (ALE) formulation… More >

  • Open Access

    ARTICLE

    MICROCANTILEVERS IN BIOMEDICAL AND THERMO/FLUID APPLICATIONS

    Khalil Khanafera, Kambiz Vafaib,*

    Frontiers in Heat and Mass Transfer, Vol.1, No.2, pp. 1-9, 2010, DOI:10.5098/hmt.v1.2.3004

    Abstract A study was conducted to demonstrate the applications of microcantilevers in biomedical and thermo/fluid fields. The deflection of the microcantilevers due to biomaterial and turbulence effects was highlighted in this work. The novel patented microcantilever assemblies that were presented in this study can increase the signal and decrease the unfavorable deflection due to flow disturbances. This work paves the road for researchers in the area microcantilever based biosensors to design efficient microsensor systems that exhibit minimal errors in the measurements. Fluid-structure interaction was also utilized to investigate some aspects of the fluid flow and heat More >

  • Open Access

    ARTICLE

    A Preconditioned JFNK Algorithm Applied to Unsteady Incompressible Flow and Fluid Structure Interaction Problems

    Peter Lucas1, Alexander H. van Zuijlen1, Hester Bijl1

    CMES-Computer Modeling in Engineering & Sciences, Vol.59, No.1, pp. 79-106, 2010, DOI:10.3970/cmes.2010.059.079

    Abstract Despite the advances in computer power and numerical algorithms over the last decades, solutions to unsteady flow problems remain computing time intensive.
    In previous work [Lucas, P.,Bijl, H., and Zuijlen, A.H. van(2010)], we have shown that a Jacobian-free Newton-Krylov (JFNK) algorithm, preconditioned with an approximate factorization of the Jacobian which approximately matches the target residual operator, enables a speed up of a factor of 10 compared to nonlinear multigrid (NMG) for two-dimensional, large Reynolds number, unsteady flow computations. Furthermore, in [Lucas, P., Zuijlen, A.H. van, and Bijl, H. (2010)] we show that this algorithm also greatly… More >

  • Open Access

    ARTICLE

    Two-phase flow in complex geometries: A diffuse domain approach

    S. Aland1, J. Lowengrub2, A. Voigt1

    CMES-Computer Modeling in Engineering & Sciences, Vol.57, No.1, pp. 77-108, 2010, DOI:10.3970/cmes.2010.057.077

    Abstract We present a new method for simulating two-phase flows in complex geometries, taking into account contact lines separating immiscible incompressible components. We combine the diffuse domain method for solving PDEs in complex geometries with the diffuse-interface (phase-field) method for simulating multiphase flows. In this approach, the complex geometry is described implicitly by introducing a new phase-field variable, which is a smooth approximation of the characteristic function of the complex domain. The fluid and component concentration equations are reformulated and solved in larger regular domain with the boundary conditions being implicitly modeled using source terms. The… More >

  • Open Access

    ARTICLE

    Numerical Simulation of Fluid-Structure Interaction of LNG Prestressed Storage Tank under Seismic Influence

    X. H. Du1, X. P. Shen1

    CMC-Computers, Materials & Continua, Vol.20, No.3, pp. 225-242, 2010, DOI:10.3970/cmc.2010.020.225

    Abstract Aim of this paper is to estimate the integrity of liquefied natural gas (LNG) prestressed storage tank under seismic influence. The coupled Eulerian-Lagrangian (CEL) analysis technique is used to simulate the fluid-structure interaction between LNG and the cylinder of LNG prestressed storage tank. The 3-D model of LNG has been dispersed by Eulerian mesh that is different from traditional analysis method which is called the added mass method. Meanwhile, both of the 3-D models of prestressed rebar and concrete structure are dispersed by Lagrangian mesh. Following conclusions are obtained: 1) Natural frequency of the whole… More >

  • Open Access

    ABSTRACT

    An advanced fluid-structure interaction approach for wing-body configuration

    Doan An1, Jae-Woo Lee2, Sang Ho Kim1, Yung-Hwan Byun1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.11, No.2, pp. 35-36, 2009, DOI:10.3970/icces.2009.011.035

    Abstract As analysis methods for the individual CFD (Computational Fluid Dynamics) and FEM (Finite Element Method) analyses are matured, many researches are going on recently and several commercial software are available and ready to use, but the application of the method is limited to the specific or relatively simple geometry. When the configuration geometry is complex or operating conditions are difficult to impose, the meshing and re-meshing process between aerodynamic analysis and FEM analysis is not an easy task and commercial software have limitations to be applied to the specific problems.
    Therefore, in this study, the aerodynamics-structure… More >

  • Open Access

    ABSTRACT

    Transient hydroplaning simulation of automotive tires using the fluid-structure interaction finite element method

    S.T. Jenq1,2, Y.S. Chiu2, Y.C. Ting2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.9, No.4, pp. 263-264, 2009, DOI:10.3970/icces.2009.009.263

    Abstract The purpose of this work is to study the transient hydroplaning behavior of inflated pneumatic 195/65R15 radial tires with various tread patterns and the tires were loaded with a quarter car weight. The tires were analyzed numerically to roll over a water film with a thickness of 5 mm, 10 mm and 15 mm on top of a flat-road pavement. Current tire structure contains the outer rubber tread and the inner advanced reinforcing composite layers. The Mooney-Rivlin constitutive law and the classical laminated theory (CLT) were used to describe the behavior of the large-deformable rubber… More >

  • Open Access

    ARTICLE

    Patient-Specific Artery Shrinkage and 3D Zero-Stress State in Multi-Component 3D FSI Models for Carotid Atherosclerotic Plaques Based on In Vivo MRI Data

    Xueying Huang*, Chun Yang, Chun Yuan, Fei Liu, Gador Canton, Jie Zheng§, Pamela K. Woodard§, Gregorio A. Sicard, Dalin Tang||

    Molecular & Cellular Biomechanics, Vol.6, No.2, pp. 121-134, 2009, DOI:10.3970/mcb.2009.006.121

    Abstract Image-based computational models for atherosclerotic plaques have been developed to perform mechanical analysis to quantify critical flow and stress/strain conditions related to plaque rupture which often leads directly to heart attack or stroke. An important modeling issue is how to determine zero stress state from in vivo plaque geometries. This paper presents a method to quantify human carotid artery axial and inner circumferential shrinkages by using patient-specific ex vivo and in vivo MRI images. A shrink-stretch process based on patient-specific in vivo plaque morphology and shrinkage data was introduced to shrink the in vivo geometry first to find the zero-stress… More >

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