YAFEI WANG^1,2,#, JIELEI NI^1,#, YUHAN LIU², DINGYING LIAO³, QIANWEN ZHOU¹, XIAOYANG JI², GANG NIU², YANXIANG NI^1,*

BIOCELL, Vol.47, No.12, pp. 2567-2578, 2023, DOI:10.32604/biocell.2023.043781

Abstract Down syndrome (DS) is a genetic condition characterized by intellectual disability, delayed brain development, and early onset Alzheimer’s disease. The use of primary neural cells and tissues is important for understanding this disease, but there are ethical and practical issues, including availability from patients and experimental manipulability. Moreover, there are significant genetic and physiological differences between animal models and humans, which limits the translation of the findings in animal studies to humans. Advancements in induced pluripotent stem cells (iPSC) technology have revolutionized DS research by providing a valuable tool for studying the cellular and molecular pathologies associated with DS. Induced… More >

Shimaa M. Amer¹, Ashraf A. M. Khalaf², Amr H. Hussein^3,4, Salman A. Alqahtani⁵, Mostafa H. Dahshan⁶, Hossam M. Kassem^3,4,*

CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.3, pp. 2749-2767, 2024, DOI:10.32604/cmes.2023.029138

Abstract Side lobe level reduction (SLL) of antenna arrays significantly enhances the signal-to-interference ratio and improves the quality of service (QOS) in recent and future wireless communication systems starting from 5G up to 7G. Furthermore, it improves the array gain and directivity, increasing the detection range and angular resolution of radar systems. This study proposes two highly efficient SLL reduction techniques. These techniques are based on the hybridization between either the single convolution or the double convolution algorithms and the genetic algorithm (GA) to develop the Conv/GA and DConv/GA, respectively. The convolution process determines the element’s excitations while the GA optimizes… More >

Jiahao Lu¹, Fangfang Zhang¹, Weilong Guang¹, Yanzhao Wu¹, Ran Tao^1,2,*, Xiaoqin Li^1,2, Ruofu Xiao^1,2

Energy Engineering, Vol.120, No.12, pp. 2819-2837, 2023, DOI:10.32604/ee.2023.042287

Abstract Savonius hydrokinetic turbine is a kind of turbine set which is suitable for low-velocity conditions. Unlike conventional turbines, Savonius turbines employ S-shaped blades and have simple internal structures. Therefore, there is a large space for optimizing the blade geometry. In this study, computational fluid dynamics (CFD) numerical simulation and genetic algorithm (GA) were used for the optimal design. The optimization strategies and methods were determined by comparing the results calculated by CFD with the experimental results. The weighted objective function was constructed with the maximum power coefficient C_p and the high-power coefficient range R under multiple working conditions. GA helps… More >

Xiaobao Yu^*, Kang Yang

Energy Engineering, Vol.120, No.12, pp. 2741-2760, 2023, DOI:10.32604/ee.2023.028041

Abstract Taking an industrial park as an example, this study aims to analyze the characteristics of a distribution network that incorporates distributed energy resources (DERs). The study begins by summarizing the key features of a distribution network with DERs based on recent power usage data. To predict and analyze the load growth of the industrial park, an improved back-propagation algorithm is employed. Furthermore, the study classifies users within the industrial park according to their specific power consumption and supply requirements. This user segmentation allows for the introduction of three constraints: node voltage, wire current, and capacity of DERs. By incorporating these… More >

QIUQIANG CHEN^1,*, XIAOLEI ZHAO², WENXUE MA^3,*

Oncology Research, Vol.32, No.1, pp. 95-98, 2024, DOI:10.32604/or.2023.046174

Abstract Greenblatt and his team have unveiled vertebral skeletal stem cells (vSSCs) as a critical player in the landscape of bone metastasis. This commentary delves into the transformative discoveries surrounding vSSCs, emphasizing their distinct role in bone metastasis compared to other stem cell lineages. We illuminate the unique properties and functions of vSSCs, which may account for the elevated susceptibility of vertebral bones to metastatic invasion. Furthermore, we explore the exciting therapeutic horizons opened by this newfound understanding. These include potential interventions targeting vSSCs, modulation of associated signaling pathways, and broader implications for the treatment and management of bone metastasis. By… More > Graphic Abstract

Lei Wang¹, Runying Wang¹, Yi Li³, Yichen Zhao^1,*, Degang Zhao^1,2,*

Phyton-International Journal of Experimental Botany, Vol.92, No.11, pp. 3063-3075, 2023, DOI:10.32604/phyton.2023.043803

Abstract Adventitious root formation poses a major constraint on the tissue culture and genetic transformation of Eucommia ulmoides. Micrografting offers a new method for the transplantation of genetic transformation, and its success depends on the formation of graft unions. This study used transgenic rootless test-tube seedlings as scions and seedlings from seed as rootstocks during micrografting to avoid the rooting issues that occur during tissue culture and to investigate the role of the EuEG1 gene in the graft healing process. We found that the EuEG1 gene is a vital regulator of graft, and its overexpression contributes to the survival of Eucommia… More >