MEI LAN^#, JINGFENG HU^#, HONGLI YANG, LIQIN ZHANG, XUEZHONG XU, JIANGMING HE^*

BIOCELL, Vol.44, No.4, pp. 751-767, 2020, DOI:10.32604/biocell.2020.012954

Abstract Clubroot of Chinese cabbage (Brassica rapa L. ssp. pekinensis), caused by the obligate parasite Plasmodiophora brassicae, accounts for serious yield losses. The aim of our study was to explore the phytohormone levels and metabolome changes in the roots of resistant and susceptible B. rapa genotypes at a late stage of infection, i.e., 28 days post-infection. Both genotypes showed decreased auxin levels after P. brassicae infection except for indole-3-acetic acid. Overall, the susceptible genotype had higher auxin and cytokinin levels after infection, with the exception of trans-zeatin and 3- indolebutyric acid as compared to the resistant genotype. Jasmonic acid levels declined… More >

Abdullah Baz^1,*, Hosam Alhakami²

CMC-Computers, Materials & Continua, Vol.66, No.2, pp. 1155-1174, 2021, DOI:10.32604/cmc.2020.013215

Abstract The World Health Organization declared COVID-19 a pandemic on March 11, 2020 stating that it is a worldwide danger and requires imminent preventive strategies to minimise the loss of lives. COVID-19 has now affected millions across 211 countries in the world and the numbers continue to rise. The information discharged by the WHO till June 15, 2020 reports 8,063,990 cases of COVID-19. As the world thinks about the lethal malady for which there is yet no immunization or a predefined course of drug, the nations are relentlessly working at the most ideal preventive systems to contain the infection. The Kingdom… More >

Tehmina Bahar^1,*, Adeeba Mahboob Qureshi¹, Fasiha Qurashi^1,2, Muniba Abid¹, Misbah Batool Zahra¹, Muhammad Saleem Haider¹

Phyton-International Journal of Experimental Botany, Vol.90, No.1, pp. 75-86, 2021, DOI:10.32604/phyton.2020.010597

Abstract Most damaging plant diseases have been caused by viruses in the entire world. In tropical and subtropical areas, the damage caused by plant virus leads to great economic and agricultural losses. Single stranded DNA viruses (geminiviruses) are the most perilous pathogens which are responsible for major diseases in agronomic and horticultural crops. Significantly begomoviruses and mastreviruses are the biggest genus of plant infecting viruses, transmitted though Bemisia tabaci and members of Cicadellidae respectively. Plants possesses some naturally existing chemicals term as phyto-chemicals which perform important functions in the plant. Some antioxidant enzymes are used by plants for self-defense upon foreign… More >

Jodi L. Feinberg¹, Frank Cecchin^1,2, Arianna Gonzalez¹, Emily Johnson², Dan G. Halpern^1,*

Congenital Heart Disease, Vol.15, No.3, pp. 141-146, 2020, DOI:10.32604/CHD.2020.012039

Abstract Adults with congenital heart disease (ACHD) are likely at increased risk for complications of COVID-19. ACHD centers should prepare to deliver routine cardiac care and support for patients with COVID-19 safely at home, as the number of COVID-19 infections worldwide continues to increase. This brief report aims to share the strategies we have used in our ACHD program to manage and treat our patients during this global health crisis at one of the initial epicenters of the pandemic in New York City, and offer suggestions for preparation for ACHD clinicians. More >

HAIFENG WANG^1,2,*, JUAN GUO¹, LIJING ZHENG¹, SHUYING LIU¹, ZHERONG WANG¹, HONGXUAN HE²

BIOCELL, Vol.44, No.2, pp. 217-224, 2020, DOI:10.32604/biocell.2020.09051

Abstract The Escherichia coli (E. coli) is prevailing worldwide, but the epidemiology of E. coli infections feature regional distribution characteristics to some extent. E. coli, as a zoonotic pathogen, can be transferred from animals to humans through food chain or via contact with wounds, causing a public health risk. We reported the swelling of proventriculus and tracheal bleeding following the death in two broiler chickens (Gallus gallus domesticus) from Beijing, China. To investigate whether a virus was involved in the infection, Madin Darby Bovine Kidney (MDCK) cells were co-cultured with supernatants of proventriculus, trachea and spleen homogenates. The avian leucosis virus… More >

Jonathan N. Johnson^1,2, Cindy S. Barrett³, Wayne H. Franklin⁴, Eric M. Graham⁵, Nancy J. Halnon⁶, Brandy A. Hattendorf⁷, Catherine D. Krawczeski⁸, James J. McGovern⁹, Matthew J. O’Connor¹⁰, Amy H. Schultz¹¹, Jeffrey M. Vinocur¹², Devyani Chowdhury¹³, Jeffrey B. Anderson¹⁴

Congenital Heart Disease, Vol.12, No.6, pp. 756-761, 2017, DOI:10.1111/chd.12519

Abstract Introduction: In 2012, the American College of Cardiology’s (ACC) Adult Congenital and Pediatric Cardiology Council established a program to develop quality metrics to guide ambulatory practices for pediatric cardiology. The council chose five areas on which to focus their efforts; chest pain, Kawasaki Disease, tetralogy of Fallot, transposition of the great arteries after arterial switch, and infection prevention. Here, we sought to describe the process, evaluation, and results of the Infection Prevention Committee’s metric design process.
Methods: The infection prevention metrics team consisted of 12 members from 11 institutions in North America. The group agreed to work on specific infection… More >

Brena Sue Haughey¹, Shelby Coral White², Michael David Seckeler²

Congenital Heart Disease, Vol.14, No.5, pp. 811-813, 2019, DOI:10.1111/chd.12809

Abstract Objective: Catheter‐associated bloodstream infections complicate and prolong hos‐ pitalizations. The incidence of catheter‐associated bloodstream infections in children undergoing congenital cardiac surgery has not been reported. This study sought to define the incidence of catheter‐associated bloodstream infections after congenital cardiac surgery in neonates and infants ≤12 months old and compare hospital out‐ comes and costs to those who underwent surgery and did not have a catheter‐associ‐ ated bloodstream infections.
Design: Retrospective review of hospital admissions between October 2013 and November 2015 for neonates and infants ≤12 months old at admission with ICD‐9 codes for congenital cardiac surgery from discharge data from… More >

Sarah Tweddell, Rohit S. Loomba, David S. Cooper, Alexis L. Benscoter

Congenital Heart Disease, Vol.14, No.5, pp. 785-790, 2019, DOI:10.1111/chd.12779

Abstract Introduction: Health care‐associated infections (HAIs) increase mortality, length of stay, and cost in hospitalized patients. The incidence of and risk factors for developing HAIs in the pediatric population after cardiac surgery have been studied. This study evaluates the impact of HAIs on length of stay, inpatient mortality, and cost of hospitalization in the pediatric population after cardiac surgery.
Methods: TheKids’InpatientDatabasewasqueriedforanalysis.Patientsunder18years of age who underwent cardiac surgery from 1997 to 2012 were included. HAIs were defined as central line‐associated blood stream infections, catheter‐associated urinary tract infections, ventilator‐associated pneumonias, and surgical wound infections. Univariate analysis compared admissions with and without a HAI.… More >

Aknur Turgumbayeva^1,2, Gulbaram Ustenova¹, Ubaidilla Datkhayev¹, Khairolla Rahimov³, Silvijus Abramavicius^4,5, Agile Tunaityte^4,*, Kairat Zhakipbekov^1,6, Kaldanay Kozhanova¹, Saken Tulemissov⁷, OzikhanUstenova⁸, Gulmira Datkayeva⁹, Edgaras Stankevicius^1,10

Phyton-International Journal of Experimental Botany, Vol.89, No.1, pp. 137-146, 2020, DOI:10.32604/phyton.2020.07665

Abstract In this research we present that Carthamus Tinctorius L. (gen. Asteraceae, otherwise known as Safflower) (Fig. 1) may contain agents active in Cryptococcal infections, malaria and Leishmaniasis, as treatment options are becoming scarce due to drug resistance development. Phytochemistry and pharmacological activities (antimicrobial, antimalarial, antileishmanial) of C. tinctorius L. were analyzed. The composition of volatile oil of safflower dried flowers was analyzed by gas chromatography-mass spectrophotometry with flame ionization detector (GC-FID) and in vitro sensitivity assays were performed to assess biological activity. 8 known and 3 unknown compounds were detected in the extract (Fig. 1). Then the Safflower ointment was… More >

Wei LI, Huihui GAO, Ran TAO, Lifang LIU, Shiqiang SHANG^*

BIOCELL, Vol.43, No.4, pp. 285-291, 2019, DOI:10.32604/biocell.2019.08177

Abstract As a response factor of interferon, tripartite motif (TRIM) 22 was reported to exert antiviral activity against viruses. In this study, THP-1 macrophages were infected with human cytomegalovirus (HCMV) to establish the HCMV lytic infection model. The mRNA levels of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α) and interferonbeta (IFN-β) were significantly up-regulated in THP-1 macrophages at different infection time and titers. Moreover, for the first time, upregulation of TRIM22 expression was found during HCMV infection at both mRNA and protein levels in THP-1 macrophages. Furthermore, IFN-β could induce TRIM22 expression in THP-1 macrophages or HCMV infected THP-1 macrophages. Depletion of… More >