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  • Open Access

    ARTICLE

    Study of Fractional Order Dynamical System of Viral Infection Disease under Piecewise Derivative

    Kamal Shah1,2, Hafsa Naz2, Thabet Abdeljawad1,3,*, Bahaaeldin Abdalla1

    CMES-Computer Modeling in Engineering & Sciences, Vol.136, No.1, pp. 921-941, 2023, DOI:10.32604/cmes.2023.025769 - 05 January 2023

    Abstract This research aims to understand the fractional order dynamics of the deadly Nipah virus (NiV) disease. We focus on using piecewise derivatives in the context of classical and singular kernels of power operators in the Caputo sense to investigate the crossover behavior of the considered dynamical system. We establish some qualitative results about the existence and uniqueness of the solution to the proposed problem. By utilizing the Newtonian polynomials interpolation technique, we recall a powerful algorithm to interpret the numerical findings for the aforesaid model. Here, we remark that the said viral infection is caused… More > Graphic Abstract

    Study of Fractional Order Dynamical System of Viral Infection Disease under Piecewise Derivative

  • Open Access

    ARTICLE

    The microRNA pathway activation in insect cell model upon Autographa californica multiple nucleopolyhedrovirus infection

    QIAOJIN JIA1,2, YUEJUN FU1,*

    BIOCELL, Vol.47, No.3, pp. 627-645, 2023, DOI:10.32604/biocell.2023.026182 - 03 January 2023

    Abstract Background: The immune system of insects exerts fundamentally different antiviral mechanisms than mammals. MicroRNAs (miRNAs) play vital roles in developing insect antiviral immunity. MiRNAs expression profiles of insects changed significantly during baculovirus infection. Methods: Differential expression profiles of miRNAs in Spodoptera frugiperda were monitored by next-generation sequencing (NGS) and RT-qPCR during Autographa californica multiple nucleopolyhedrovirus (AcMNPV) infection. The transcription levels of genes were detected by RT-qPCR. The 50% tissue culture infective dose (TCID50) endpoint dilution assay was used to determine the proliferation of progeny virus. Results: NGS revealed that 49 miRNAs were differentially expressed in Sf9 cells, and 10… More >

  • Open Access

    ARTICLE

    Numerical Procedure for Fractional HBV Infection with Impact of Antibody Immune

    Sakda Noinang1, Zulqurnain Sabir2, Muhammad Asif Zahoor Raja3, Soheil Salahshour4, Wajaree Weera5,*, Thongchai Botmart5

    CMC-Computers, Materials & Continua, Vol.74, No.2, pp. 2575-2588, 2023, DOI:10.32604/cmc.2023.029046 - 31 October 2022

    Abstract The current investigations are presented to solve the fractional order HBV differential infection system (FO-HBV-DIS) with the response of antibody immune using the optimization based stochastic schemes of the Levenberg-Marquardt backpropagation (LMB) neural networks (NNs), i.e., LMBNNs. The FO-HBV-DIS with the response of antibody immune is categorized into five dynamics, healthy hepatocytes (H), capsids (D), infected hepatocytes (I), free virus (V) and antibodies (W). The investigations for three different FO variants have been tested numerically to solve the nonlinear FO-HBV-DIS. The data magnitudes are implemented 75% for training, 10% for certification and 15% for testing More >

  • Open Access

    ARTICLE

    Transcriptome Analysis of a Wild Eggplant Germplasm M239 in Response to Verticillium dahliae Infection

    Liyan Wu1, Jie Cheng1,2, Yaju Gong1, Rui Bao1, Zhibin Li1, Min Gui1,*, Guanghui Du2,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.2, pp. 591-609, 2023, DOI:10.32604/phyton.2022.023481 - 12 October 2022

    Abstract In this study, wild eggplant germplasm No. M239, which is highly susceptible to Verticillium wilt, was used as the experimental material. The physiological and biochemical indices (SOD, PAL, MDA and soluble protein) of M239 roots were measured at different times (0, 12, 24, 36, 48, 60 and 72 h) post inoculation with Verticillium dahliae, and the key time points for the M239 response to Verticillium wilt infection were screened. Then, RNA-Seq technology was used to screen the differentially expressed genes (DEGs) in M239 roots at 0, 12 and 48 h post-inoculation (hpi). The transcriptional results of M239… More >

  • Open Access

    ARTICLE

    Characterization and Pathogenicity of Pseudopestalotiopsis vietnamensis Causing Gray Blight of Wuyi Rock Tea (Camellia sinensis) in China and Specific Mechanisms of Disease Infection

    Guangheng Wu1,#,*, Lu Rui2,3,#, Xiang Lu4, Libo Han2, Gan Lv1, Xianyu Fu5, Jinxian Liu5, Nong Zhou3, Chuanhai Zhang1

    Phyton-International Journal of Experimental Botany, Vol.92, No.1, pp. 131-147, 2023, DOI:10.32604/phyton.2022.021919 - 06 September 2022

    Abstract Gray blight disease (GBD) causes significant losses in tea production in China. Although genes and biological processes involved in resistance to fungal disease in tea plants have been identified, specific mechanisms of the GBD infection process remain unknown. In this study, morphological and multi-gene (TEF-TUB-ITS) phylogenetic characteristics were used to identify isolate CLBB1 of Pseudopestalotiopsis vietnamensis. Pathogenicity tests confirmed that isolate CLBB1 from tea leaves caused GBD in the susceptible tea cultivar Wuyi Rock (Camellia sinensis var. sinensis cv. Shuixian). Spores began to germinate 24 h after infection (hai), and after 48 h, elongated fungal hyphae formed from a single More >

  • Open Access

    ARTICLE

    Rice Bacterial Infection Detection Using Ensemble Technique on Unmanned Aerial Vehicles Images

    Sathit Prasomphan*

    Computer Systems Science and Engineering, Vol.44, No.2, pp. 991-1007, 2023, DOI:10.32604/csse.2023.025452 - 15 June 2022

    Abstract Establishing a system for measuring plant health and bacterial infection is critical in agriculture. Previously, the farmers themselves, who observed them with their eyes and relied on their experience in analysis, which could have been incorrect. Plant inspection can determine which plants reflect the quantity of green light and near-infrared using infrared light, both visible and eye using a drone. The goal of this study was to create algorithms for assessing bacterial infections in rice using images from unmanned aerial vehicles (UAVs) with an ensemble classification technique. Convolution neural networks in unmanned aerial vehicles image… More >

  • Open Access

    REVIEW

    Clinical relevance and therapeutic potential of IL-38 in immune and non-immune-related disorders

    Mohammad Reza Haghshenas1, Mina Roshan Zamir1, Mahboubeh Sadeghi1, Mohammad Javad Fattahi1, Kimia Mirshekari1, Abbas Ghaderi1,2,*

    European Cytokine Network, Vol.33, No.3, pp. 54-69, 2022, DOI:10.1684/ecn.2022.0480

    Abstract Interleukin-38 (IL-38) is the most recent member of the IL-1 family that acts as a natural inflammatory inhibitor by binding to cognate receptors, particularly the IL-36 receptor. In vitro, animal and human studies on autoimmune, metabolic, cardiovascular and allergic diseases, as well sepsis and respiratory viral infections, have shown that IL-38 exerts an anti-inflammatory activity by modulating the generation and function of inflammatory cytokines (e.g. IL-6, IL-8, IL-17 and IL-36) and regulating dendritic cells, M2 macrophages and regulatory T cells (Tregs). Accordingly, IL-38 may possess therapeutic potential for these types of diseases. IL-38 down-regulates CCR3+… More >

  • Open Access

    ARTICLE

    Risk factors for postoperative Clostridium difficile infection after radical cystectomy for bladder cancer: a NSQIP database analysis

    Canadian Journal of Urology, Vol.29, No.3, pp. 11170-11174, 2022

    Abstract Introduction: Patients undergoing cystectomy for bladder cancer are at an increased risk for Clostridium difficile infection (CDI) due to prolonged antibiotics and underlying comorbidities. We aim to evaluate CDI risk factors in cystectomy patients.
    Materials and methods: Utilizing National Surgical Quality Improvement Program (NSQIP), patients undergoing cystectomy with diagnosis of bladder cancer between 2015-2017 were included. Baseline demographics including age, sex, comorbidities, and preoperative labs were collected. Univariate and multivariable logistic regression were used to evaluate risk factors for and complications of CDI during the index hospitalization.
    Results: There were a total of 6,432 patients included in the… More >

  • Open Access

    ARTICLE

    Patient and caretaker satisfaction with the PureWick system

    Lakshay Khosla1, Johan Mohd Sani2, Bilal Chughtai3

    Canadian Journal of Urology, Vol.29, No.4, pp. 11216-11223, 2022

    Abstract Introduction: The BD PureWick System (PureWick) allows for non-invasive management of urinary incontinence (UI) by using a low-pressure suction to wick urine from an external catheter into a collection canister. The purpose of this study was to assess satisfaction of using PureWick for management of UI in the outpatient setting based on patient and caregiver feedback.
    Materials and methods: Patients and caregivers utilizing PureWick completed an online questionnaire between August and October 2020. Factors evaluated included demographics, satisfaction, recommendations, and claims using multiple choice questions, checklists, 6-point Likert Scale, and open-ended questions. Patient and caregiver responses were… More >

  • Open Access

    ARTICLE

    Testicular schistosomiasis: a systematic review of the literature

    Azadeh Nazemi, Jesse Persily, James S. Wysock

    Canadian Journal of Urology, Vol.29, No.6, pp. 11366-11370, 2022

    Abstract Introduction: To consolidate reported information on presentation, diagnosis, and treatment modalities in testicular schistosomiasis (TS) to provide a reference tool for this rare disease.
    Materials and methods: A comprehensive PubMed search was performed using PRISMA guidelines, which yielded 21 articles detailing 22 cases of TS.
    Results: Testicular schistosomiasis remains a rare disease, presenting at a variety of ages (median age 27). All reports of this condition are associated with exposure to an endemic area. The most common presenting symptoms include nonspecific testicular swelling (54.5%) followed by a testicular mass/nodule (18.4%). Diagnosis relies upon clinical suspicion due to low… More >

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