Piyush Kumar Gupta¹, D. Karthik Kumar², M. Thaveena³, Soumya Pandit¹, Somya Sinha⁴, R. Ranjithkumar^2,* , Walaa F. Alsanie⁵, Vijay Kumar Thakur^6,7,8,*

Journal of Renewable Materials, Vol.10, No.12, pp. 3093-3105, 2022, DOI:10.32604/jrm.2022.019335

Abstract Custard apple is a dry land fruit. Its leaves exhibit different pharmacological activities. In the present study, both silver (Ag) nanoparticles and chitosan-coated Ag (Chi-Ag) nanoparticles were fabricated using the aqueous leaf extract of the custard apple plant. During preliminary phytochemical analysis, various types of phytocompounds were found in the aqueous leaf extract of the same plant. Next, both nanoparticles were physiochemically characterized. FTIR analysis exhibited the fingerprint vibrational peaks of active bioactive compounds in plant extract, Ag nanoparticles, and Chi-Ag nanoparticles. UV/Visible spectral analysis revealed the highest absorbance peak at 419 nm, indicating the presence of Ag nanoparticles. XRD… More > Graphic Abstract

ADRIANA L. FERREIRA, GUSTAVO C. PARIS, ALINE DE A. AZEVEDO, ERIKA A. C. CORTEZ, SIMONE N. CARVALHO, LAIS DE CARVALHO, ALESSANDRA A. THOLE^*

BIOCELL, Vol.46, No.8, pp. 1807-1813, 2022, DOI:10.32604/biocell.2022.019363

Abstract Mesenchymal stem cells (MSC) have pushed the field of stem cell-based therapies by inducing tissue regeneration, immunosuppression, and angiogenesis mainly through vesicles and soluble factors release (paracrine signaling). MSC-extracellular vesicles (MSC-EV) adaptable secretome and homing to injured sites allowed researchers to unlock a new era of cell-free based therapy. In parallel, nanoparticles (NP) have been explored in contributing to transport and drug delivery systems, giving drugs desired physical-chemical properties to exploit cell behavior. However, NPs can be quickly recognized by immune cells and cleared from circulation. In this viewpoint, we explore how combining both therapeutic strategies can improve efficacy and… More >

D. Devina Merin^1,*, P. Jagatheeswari²

Intelligent Automation & Soft Computing, Vol.33, No.3, pp. 1849-1860, 2022, DOI:10.32604/iasc.2022.024495

Abstract The Deep learning (DL) network is an effective technique that has extended application in medicine, robotics, biotechnology, biometrics and communication. The unique architecture of DL networks can be trained according to classify any complex tasks in a limited duration. In the proposed work a deep convolution neural network of DL is trained to classify the antimicrobial activity of silver nanoparticles (AgNP). The process involves two processing steps; synthesis of silver nanoparticles and classification (SEM) of AgNP based on the antimicrobial activity. AgNP images from scanning electron microscope are pre-processed using Adaptive Histogram Equalization in the networking system and the DL… More >

Arpita Roy^1,*, H. C. Ananda Murthy² , Hiwa M. Ahmed^3,4, Mohammad Nazmul Islam⁵, Ram Prasad^6,*

Journal of Renewable Materials, Vol.10, No.7, pp. 1911-1930, 2022, DOI:10.32604/jrm.2022.019410

Abstract Now-a-days nanotechnology is one of the booming fields for the researchers. With the increase in industrialization mainly textile, paper, medicine, plastic industry, there is an increase in concentration of organic dyes as pollutant. Release of harmful dyes in water bodies has become a serious issue, as most of the dyes are carcinogenic and mutagenic in nature and causes various diseases. Therefore, there is a requirement to find out new approaches for efficient treatment of effluent containing dyes. Nanoparticles are one of the potential solutions to this problem. They can be synthesized from different methods, however synthesis of nanoparticles from different… More >

Xing Zhou^*

Journal of Renewable Materials, Vol.10, No.6, pp. 1623-1639, 2022, DOI:10.32604/jrm.2022.018935

Abstract A facile method, focusing on emulsification, chain extension and dispersion process in preparing waterborne polyurethane, was developed to prepare emulsion with rod-like nanoparticles. The facile method involves a water addition procedure by in situ generated water to react with polyurethane prepolymer instead of the external water addition process. As a comparison, waterborne polyurethane was synthesized through the external water addition process. According to the characterization methods including FTIR, ¹H-NMR, TEM and water swelling experiments, it is suggested there are two kinds of hydrogen bonds interactions in hard/soft domain of the novel polyurethane, and the phase separation of hard/soft domains increases… More > Graphic Abstract

WEI PAN^1,2,3,*, YE HE¹, MENGDONG HE^1,2,3, FEI WANG^1,2,3, LIHUA QIU^1,2

BIOCELL, Vol.46, No.4, pp. 1079-1088, 2022, DOI:10.32604/biocell.2022.016934

Abstract Photodynamic therapy (PDT) has emerged as a novel therapeutic modality for cancer treatment, but its therapeutic efficacy is severely limited by the hypoxic tumor microenvironment (TME). Here we designed an innovative multifunctional nano-platform which consists of a hollow MnO₂ shell and internal photosensitizer IR780. It is not only used for multimodal imaging of oral squamous cell carcinoma (OSCC), but also for adjustment hypoxic TME to enhance cancer treatment. Hollow MnO₂ can promote decomposition of tumor endogenous H₂O₂ to relieve tumor hypoxia, thereby enhancing the effect of photodynamic therapy. Photosensitizer IR780 generates singlet oxygen under laser irradiation to kill tumor cells,… More >

Muhammad Zafar^1,#,*, Muhammad Saif Ullah^1,#, Tareq Manzoor², Muddassir Ali³, Kashif Nazar⁴, Shaukat Iqbal⁵, Habib Ullah Manzoor⁶, Rizwan Haider¹, Woo Young Kim^7,*

CMES-Computer Modeling in Engineering & Sciences, Vol.130, No.2, pp. 723-749, 2022, DOI:10.32604/cmes.2022.017257

Abstract In recent years, the emergence of nanotechnology experienced incredible development in the field of medical sciences. During the past decade, investigating the characteristics of nanoparticles during fluid flow has been one of the intriguing issues. Nanoparticle distribution and uniformity have emerged as substantial criteria in both medical and engineering applications. Adverse effects of chemotherapy on healthy tissues are known to be a significant concern during cancer therapy. A novel treatment method of magnetic drug targeting (MDT) has emerged as a promising topical cancer treatment along with some attractive advantages of improving efficacy, fewer side effects, and reduce drug dose. During… More >

ABDELKADER HASSANI^1,2,3, SITI ASLINA HUSSAIN², MOTHANNA SADIQ AL-QUBAISI⁴, MOHAMED LAKHDER BELFAR³, HAKIM BELKHALFA⁵, HAMID HAMMAD ENEZEI⁶, HAMID ZENTOU², WISAM NABEEL IBRAHIM^7,8,*, ABD ALMONEM DOOLAANEA^1,*

BIOCELL, Vol.46, No.3, pp. 677-687, 2022, DOI:10.32604/biocell.2022.016848

Abstract The main purpose of the study was to enhance the stability and therapeutic effects of Curcumin (Cur) through nanoformulation with gum Arabic (GA) as a coating agent through an efficient synthetic approach. The antioxidant properties of the developed nanoparticles (Cur/GANPs) were assessed through several in vitro assays, such as β-carotene bleaching activity, DPPH, and nitric oxide scavenging activities in addition to evaluating its inhibitory activity on angiotensin-converting enzyme (ACE). The cytotoxicity of Cur/GANPs was evaluated in vitro using different types of human cancer cells including breast cancer (MCF7, MDA-MB231), liver cancer (HepG2), and colon cancer (HT29) cells. The prepared particles… More >

Dmitrii Kuzmenkov^1,*, Pavel Struchalin^1,2, Yulia Litvintsova¹, Maksim Delov¹, Vladimir Skrytnyy¹, Kirill Kutsenko¹

FDMP-Fluid Dynamics & Materials Processing, Vol.18, No.1, pp. 1-14, 2022, DOI:10.32604/fdmp.2022.018526

Abstract

Nanofluids have great potential for solar energy harvesting due to their suitable optical and thermophysical properties. One of the promising applications of nanofluids is utilization in solar collectors with the direct absorption of light (DASC). The design of a DASC requires detailed knowledge of the optical properties of nanofluids, which can be significantly affected by the particle size distribution. The paper presents the method to take into account the particle size distribution when calculating nanofluid extinction spectra. To validate the proposed model, the particle size distribution and spectral absorbance were measured for aqueous suspension with multi-walled graphite nanotubes; the minimum… More >

A. F. Mohamed^1,2, J. Abu Alsoud¹, Mujahed Al-Dhaifallah^3,*, Hegazy Rezk^4,5, Mohamed K. Hassan^1,6

CMC-Computers, Materials & Continua, Vol.71, No.1, pp. 71-83, 2022, DOI:10.32604/cmc.2022.019257

Abstract In power plants, flue gases can cause severe corrosion damage in metallic parts such as flue ducts, heat exchangers, and boilers. Coating is an effective technique to prevent this damage. A robust fuzzy model of the surface roughness (R_a and R_z) of flue gas ducts coated by protective composite coating from epoxy and nanoparticles was constructed based on the experimental dataset. The proposed model consists of four nanoparticles (ZnO, ZrO₂, SiO₂, and NiO) with 2%, 4%, 6%, and 8%, respectively. Response surface methodology (RSM) was used to optimize the process parameters and identify the optimal conditions for minimum surface roughness… More >