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  • Open Access

    PROCEEDINGS

    The Effect of Heating Rate on Sintering Mechanism of Alumina Nanoparticles

    Dangqiang Wang1, Hai Mei1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.27, No.1, pp. 1-1, 2023, DOI:10.32604/icces.2023.09455

    Abstract The densification process of sintered alumina is mainly controlled by surface, lattice, and interface diffusion, and many experimental researches show that heating rate can affect the transfer of matter. Thus, to further reveal the effect of heating rate on sintering mechanism of alumina nanoparticle, molecular dynamic simulations were performed at five different heating rates to examine the migration of atoms and evolution of microstructure in heating stage. Results show that the sintering process of heating is a typical thermal activation process. High displacement response temperature is caused by high heating rate, which results in the More >

  • Open Access

    REVIEW

    Development of micro/nanostructured‒based biomaterials with biomedical applications

    AFAF ALHARTHI*

    BIOCELL, Vol.47, No.8, pp. 1743-1755, 2023, DOI:10.32604/biocell.2023.027154 - 28 August 2023

    Abstract Natural biomaterials are now frequently used to build biocarrier systems, which can carry medications and biomolecules to a target region and achieve a desired therapeutic effect. Biomaterials and polymers are of great importance in the synthesis of nanomaterials. The recent studies have tended to use these materials because they are easily obtained from natural sources such as fungi, algae, bacteria, and medicinal plants. They are also biodegradable, compatible with neighborhoods, and non-toxic. Natural biomaterials and polymers are chemically changed when they are linked by cross linking agents with other polymers to create scaffolds, matrices, composites, More >

  • Open Access

    ARTICLE

    Targeting LncRNA LLNLR-299G3.1 with antisense oligonucleotide inhibits malignancy of esophageal squamous cell carcinoma cells in vitro and in vivo

    LI TIAN1,#, YONGYI HUANG1,#, BAOZHEN ZHANG2,#, YI SONG1,#, LIN YANG3, QIANQIAN CHEN1, ZHENG WANG3, YILING WANG1, QIHAN HE1, WENHAN YANG1, SHUYONG YU4, TIANYU LU5, ZICHEN LIU1, KAIPING GAO1,*, XIUJUN FAN2,*, JIAN SONG4,*, RIHONG ZHAI1,*

    Oncology Research, Vol.31, No.4, pp. 463-479, 2023, DOI:10.32604/or.2023.028791 - 25 June 2023

    Abstract Accumulating evidence has indicated that long non-coding RNAs (lncRNAs) play critical roles in the development and progression of cancers, including esophageal squamous cell carcinoma (ESCC). However, the mechanisms of lncRNAs in ESCC are still incompletely understood and therapeutic attempts for in vivo targeting cancer-associated lncRNA remain a challenge. By RNA-sequencing analysis, we identified that LLNLR-299G3.1 was a novel ESCC-associated lncRNA. LLNLR-299G3.1 was up-regulated in ESCC tissues and cells and promoted ESCC cell proliferation and invasion. Silencing of LLNLR-299G3.1 with ASO (antisense oligonucleotide) resulted in opposite effects. Mechanistically, LLNLR-299G3.1 bound to cancer-associated RNA binding proteins and regulated the expression… More >

  • Open Access

    REVIEW

    Mechanisms and applications of antitumor immunotherapy of responsive drug-loaded nanoparticles in breast cancer

    LETIAN JIN, HETING CHEN, QI RUAN, RUI LIU, YIFENG FAN, XIUFANG XU, DAJIANG WANG*, JIAHUI LU*

    BIOCELL, Vol.47, No.7, pp. 1483-1498, 2023, DOI:10.32604/biocell.2023.028457 - 21 June 2023

    Abstract During the chemotherapy of tumors, the cytotoxic effect of drugs is vital to kill tumor cells, and the delivery of a chemotherapeutic agent is of great importance for optimal therapeutic effects. The high in vivo clearance rate and low delivery efficiency of conventional chemotherapeutic agents affect the therapeutic effect. In recent years, the responsive drug delivery nanosystem has received increasing concern owing to its excellent biocompatibility, stable delivery performance, and controlled drug release strategies. To lucidly explain the cytocidal and immunotherapeutic effects of such responsive nanosystems in breast cancer, this review discusses the various stimuli and More >

  • Open Access

    ARTICLE

    Lipid Production, Oxidative Status, Antioxidant Enzymes and Photosynthetic Efficiency of Coccomyxa chodatii SAG 216-2 in Response to Calcium Oxide Nanoparticles

    Huwida A. A. Abdel-Kader1, Naeima Yousef1, Mohammad Anwar Hossain2,*, Mona F. A. Dawood1,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.7, pp. 1955-1974, 2023, DOI:10.32604/phyton.2023.028583 - 29 May 2023

    Abstract The extensive use of nanoparticles (NPs) in diverse applications causes their localization to aquatic habitats, affecting the metabolic products of primary producers in aquatic ecosystems, such as algae. Synthesized calcium oxide nanoparticles (CaO NPs) are of the scarcely studied NPs. Thus, the current work proposed that the exposure to CaO NPs may instigate metabolic pathway to be higher than that of normally growing algae, and positively stimulate algal biomass. In this respect, this research was undertaken to study the exposure effect of CaO NPs (0, 20, 40, 60, 80, and 100 µg mL−1 ) on the… More >

  • Open Access

    ARTICLE

    Inhibition of H2O2-induced TM3 cell apoptosis by oxidative stress by lentinan functionalized selenium nanoparticles through JAK2/STAT-3 and P53 pathways

    MIAOMIAO LI1,#, ZILIN ZHENG1,#, JUNYI KE1, JIEYI LUO1, FAN JIANG1, YANXIA QU1, BING ZHU2, YINGHUA LI2,*, LIANDONG ZUO1,*

    BIOCELL, Vol.47, No.6, pp. 1397-1405, 2023, DOI:10.32604/biocell.2023.027971 - 19 May 2023

    Abstract Background: Nano-selenium has been widely used in antiviral and anticancer therapy, and has the advantages of good targeting and low toxicity. For the first time, we combined male reproduction with nano-selenium to investigate its antioxidant effect. This study investigated the protective effect of lentinan functionalized selenium nanoparticles on oxidative stress injury of the hydrogen peroxide (H2O2)-induced Leydig cell line, TM3. Methods: The suitable concentration of nano-selenium treatment to promote cell proliferation was also discussed. The concentration of 4 μM could significantly promote the growth of TM3 cells. Oxidative stress damage was caused using an 800 μM concentration… More >

  • Open Access

    ARTICLE

    In Situ Generation of Copper Nanoparticles in Heat-Treated Copper-Containing Masson’s Pine as a Preservative Process for Sawn Timber

    Minting Lai, Guijun Xie*, Wanju Li, Lamei Li, Yongjian Cao

    Journal of Renewable Materials, Vol.11, No.6, pp. 2665-2678, 2023, DOI:10.32604/jrm.2023.027441 - 27 April 2023

    Abstract Heat-treated wood has good dimensional stability, durability, and color, but its susceptibility to fungal growth affects its commercial value. In this study, lumber harvested from mature Masson’s pine (Pinus massoniana Lamb.) was vacuum impregnated with a basic copper salt solution (copper hydroxide, diethanolamine, and polyethylene glycol 200) prior to heat-treatment at 220°C for 3 h. Antifungal properties, surface chemistry, crystal structure and sugar contents were tested, compared with heat treatment alone. The results showed that the samples treated by heating without copper salt treatment showed poor suppression of fungal growth, the copper-impregnated heat-treated wood suppressed (100%) the… More >

  • Open Access

    ARTICLE

    Impact of ZnSO and ZnO Nanoparticles on Seed Germination and Seedling Growth of Lettuce

    Adalberto Benavides-Mendoza1, Rebeca Betancourt-Galindo2, Nazario Francisco-Francisco3,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.6, pp. 1831-1840, 2023, DOI:10.32604/phyton.2023.028085 - 11 April 2023

    Abstract

    Micronutrient nanoparticles (NPs) are currently an option for chemical fertilization and biostimulation in crops. However, there is little information on the phytotoxic or biostimulatory effects of NPs at low concentrations of some elements, such as Zn. In this study, the effect of low concentrations of Zn oxide (ZnO) NPs on germination, growth variables, and nutritional attributes of lettuce (Lactuca sativa L.) was evaluated in comparison to Zn sulfate. Romaine lettuce seeds were treated with ZnSO4-- × 7H2O and ZnO NPs at Zn molar concentrations of 1 × 10−3, 5 × 10−3, 1 × 10−4, 5 × 10−4, 1

    More >

  • Open Access

    REVIEW

    Synthesis of Metallic Nanoparticles Based on Green Chemistry and Their Medical Biochemical Applications: Synthesis of Metallic Nanoparticles

    Kakudji Kisimba1, Anand Krishnan2,*, Mbuso Faya1, Kahumba Byanga3, Kabange Kasumbwe4, Kaliyapillai Vijayakumar5, Ram Prasad6,*

    Journal of Renewable Materials, Vol.11, No.6, pp. 2575-2591, 2023, DOI:10.32604/jrm.2023.026159 - 27 April 2023

    Abstract Nanoparticles have distinct properties that make them potentially valuable in a variety of industries. As a result, emerging approaches for the manufacture of nanoparticles are gaining a lot of scientific interest. The biological pathway of nanoparticle synthesis has been suggested as an effective, affordable, and environmentally safe method. Synthesis of nanoparticles through physical and chemical processes uses unsafe materials, expensive equipment and adversely affects the environment. As a result, in order to support the increased utilization of nanoparticles across many sectors, nanotechnology research activities have shifted toward environmentally safe and cost-effective techniques that outperform chemical… More > Graphic Abstract

    Synthesis of Metallic Nanoparticles Based on Green Chemistry and Their Medical Biochemical Applications: Synthesis of Metallic Nanoparticles

  • Open Access

    ARTICLE

    The Antibacterial Activities of Copper Oxide Nanoparticles Synthesized Using Laser Ablation in Different Surfactants against Streptococcus mutans

    Ruaa H. Abbas1, A. Kadhim1,*, Azhar M. Haleem2

    Journal of Renewable Materials, Vol.11, No.5, pp. 2109-2123, 2023, DOI:10.32604/jrm.2023.025112 - 13 February 2023

    Abstract Copper oxide nanoparticles (CuO NPs) were synthesised with laser ablation of a copper sheet immersed in deionized water (DW), cetrimonium bromide (CTAB), and sodium dodecyl sulphate (SDS), respectively. The target was irradiated with a pulsed Nd: YAG laser at 1064 nm, 600 mJ, a pulse duration of 10 ns, and a repetition rate of 5 Hz. The CuO NPs colloidal were analyzed using UV–Vis spectroscopy, the Fourier transform infrared (FTIR) spectrometer, zeta potential (ZP), X-ray diffraction (XRD), transmission electron microscope (TEM) and field emission scanning electron microscopy (FESEM). The absorption spectra of CuO NPs colloidal… More >

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