Tianyi Li^1,2, Xin Gu², Qing Zhang^2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 339-361, 2024, DOI:10.32604/cmes.2024.047566

Abstract This study proposes a comprehensive, coupled thermomechanical model that replaces local spatial derivatives in classical differential thermomechanical equations with nonlocal integral forms derived from the peridynamic differential operator (PDDO), eliminating the need for calibration procedures. The model employs a multi-rate explicit time integration scheme to handle varying time scales in multi-physics systems. Through simulations conducted on granite and ceramic materials, this model demonstrates its effectiveness. It successfully simulates thermal damage behavior in granite arising from incompatible mineral expansion and accurately calculates thermal crack propagation in ceramic slabs during quenching. To account for material heterogeneity, the model utilizes the Shuffle algorithm… More >

Chengkan Xu^1,2,4, Xiaofei Wang³, Yixuan Li², Guannan Wang^2,*, He Zhang^2,4,*

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 957-974, 2024, DOI:10.32604/cmes.2024.047327

Abstract Structural damage in heterogeneous materials typically originates from microstructures where stress concentration occurs. Therefore, evaluating the magnitude and location of localized stress distributions within microstructures under external loading is crucial. Repeating unit cells (RUCs) are commonly used to represent microstructural details and homogenize the effective response of composites. This work develops a machine learning-based micromechanics tool to accurately predict the stress distributions of extracted RUCs. The locally exact homogenization theory efficiently generates the microstructural stresses of RUCs with a wide range of parameters, including volume fraction, fiber/matrix property ratio, fiber shapes, and loading direction. Subsequently, the conditional generative adversarial network… More > Graphic Abstract

Wenjun Zhou^1,2, Mingzhi Yang¹, Qian Peng², Yong Peng^1,*, Kui Wang¹, Qiang Xiao¹

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 735-755, 2024, DOI:10.32604/cmes.2024.047258

Abstract The widespread adoption of aluminum alloy electric buses, known for their energy efficiency and eco-friendliness, faces a challenge due to the aluminum frame’s susceptibility to deformation compared to steel. This issue is further exacerbated by the stringent requirements imposed by the flammability and explosiveness of batteries, necessitating robust frame protection. Our study aims to optimize the connectors of aluminum alloy bus frames, emphasizing durability, energy efficiency, and safety. This research delves into Multi-Objective Coordinated Optimization (MCO) techniques for lightweight design in aluminum alloy bus body connectors. Our goal is to enhance lightweighting, reinforce energy absorption, and improve deformation resistance in… More >

Hayder Kareem Sakran^1,2, Mohd Sharizal Abdul Aziz^1,*, Chu Yee Khor³

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 109-137, 2024, DOI:10.32604/cmes.2024.047245

Abstract The centrifugal pump is a prevalent power equipment widely used in different engineering patterns, and the impeller blade wrap angle significantly impacts its performance. A numerical investigation was conducted to analyze the influence of the blade wrap angle on flow characteristics and energy distribution of a centrifugal pump evaluated as a low specific speed with a value of 69. This study investigates six impeller models that possess varying blade wrap angles (95°, 105°, 115°, 125°, 135°, and 145°) that were created while maintaining the same volute and other geometrical characteristics. The investigation of energy loss was conducted to evaluate the… More > Graphic Abstract

Wenxiang Dong, H. Vicky Zhao^*

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 139-170, 2024, DOI:10.32604/cmes.2024.047156

Abstract Understanding and modeling individuals’ behaviors during epidemics is crucial for effective epidemic control. However, existing research ignores the impact of users’ irrationality on decision-making in the epidemic. Meanwhile, existing disease control methods often assume users’ full compliance with measures like mandatory isolation, which does not align with the actual situation. To address these issues, this paper proposes a prospect theory-based framework to model users’ decision-making process in epidemics and analyzes how irrationality affects individuals’ behaviors and epidemic dynamics. According to the analysis results, irrationality tends to prompt conservative behaviors when the infection risk is low but encourages risk-seeking behaviors when… More >

T. Aghalya, R. Tamizharasi^*

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 431-460, 2024, DOI:10.32604/cmes.2024.046635

Abstract In this study, the characteristics of heat transfer on an unsteady magnetohydrodynamic (MHD) Casson nanofluid over an exponentially accelerated vertical porous plate with rotating effects were investigated. The flow was driven by the combined effects of the magnetic field, heat radiation, heat source/sink and chemical reaction. Copper oxide () and titanium oxide () are acknowledged as nanoparticle materials. The nondimensional governing equations were subjected to the Laplace transformation technique to derive closed-form solutions. Graphical representations are provided to analyze how changes in physical parameters, such as the magnetic field, heat radiation, heat source/sink and chemical reaction, affect the velocity, temperature… More >

Ying Wang^1,*, Longxiao Chao¹, Jun Chen², Songbai Jiang¹

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 201-227, 2024, DOI:10.32604/cmes.2024.046129

Abstract In order to investigate the fatigue performance of orthotropic anisotropic steel bridge decks, this study realizes the simulation of the welding process through elastic-plastic finite element theory, thermal-structural sequential coupling, and the birth-death element method. The simulated welding residual stresses are introduced into the multiscale finite element model of the bridge as the initial stress. Furthermore, the study explores the impact of residual stress on crack propagation in the fatigue-vulnerable components of the corroded steel box girder. The results indicate that fatigue cracks at the weld toe of the top deck, the weld root of the top deck, and the… More > Graphic Abstract

JIA SHAO^1,2, CAN ZHANG², YAONAN TANG², AIQIN HE², WEIPEI ZHU^1,*

BIOCELL, Vol.48, No.4, pp. 571-580, 2024, DOI:10.32604/biocell.2024.049092

Abstract Objective: Previous studies indicated that aberrant circular RNA (circRNA) expression affects gene expression regulatory networks, leading to the aberrant activation of tumor pathways and promoting tumor cell growth. However, the expression, clinical significance, and effects on cell propagation, invasion, and dissemination of circRNA_001896 in cervical cancer (CC) tissues remain unclear. Methods: The Gene Expression Omnibus (GEO) datasets (GSE113696 and GSE102686) were used to examine differential circRNA expression in CC and adjacent tissues. The expression of circRNA_001896 was detected in 72 CC patients using fluorescence quantitative PCR. Correlation analysis with clinical pathological features was performed through COX multivariate and univariate analysis.… More >

YARA ALZGHOUL, HALA J. BANI ISSA, AHMAD K. SANAJLEH, TAQWA ALABDUH, FATIMAH RABABAH, MAHA AL-SHDAIFAT, EJLAL ABU-EL-RUB^*, FATIMAH ALMAHASNEH, RAMADA R. KHASAWNEH, AYMAN ALZU’BI, HUTHAIFA MAGABLEH

BIOCELL, Vol.48, No.4, pp. 559-569, 2024, DOI:10.32604/biocell.2024.048056

Abstract Mesenchymal stem cells (MSCs) are ideal candidates for treating many cardiovascular diseases. MSCs can modify the internal cardiac microenvironment to facilitate their immunomodulatory and differentiation abilities, which are essential to restore heart function. MSCs can be easily isolated from different sources, including bone marrow, adipose tissues, umbilical cord, and dental pulp. MSCs from various sources differ in their regenerative and therapeutic abilities for cardiovascular disorders. In this review, we will summarize the therapeutic potential of each MSC source for heart diseases and highlight the possible molecular mechanisms of each source to restore cardiac function. More >

FREDERICK H. SILVER^1,2,*, TANMAY DESHMUKH²

BIOCELL, Vol.48, No.4, pp. 525-540, 2024, DOI:10.32604/biocell.2024.047965

Abstract All tissues in the body are subjected externally to gravity and internally by collagen fibril and cellular retractive forces that create stress and energy equilibrium required for homeostasis. Mechanotransduction involves mechanical work (force through a distance) and energy storage as kinetic and potential energy. This leads to changes in cell mitosis or apoptosis and the synthesis or loss of tissue components. It involves the application of energy directly to cells through integrin-mediated processes, cell-cell connections, stretching of the cell cytoplasm, and activation of the cell nucleus via yes-associated protein (YAP) and transcriptional coactivator with PDZ-motif (TAZ). These processes involve numerous… More >