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  • Open Access

    ARTICLE

    Unsteady MHD Casson Nanofluid Flow Past an Exponentially Accelerated Vertical Plate: An Analytical Strategy

    T. Aghalya, R. Tamizharasi*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 431-460, 2024, DOI:10.32604/cmes.2024.046635

    Abstract In this study, the characteristics of heat transfer on an unsteady magnetohydrodynamic (MHD) Casson nanofluid over an exponentially accelerated vertical porous plate with rotating effects were investigated. The flow was driven by the combined effects of the magnetic field, heat radiation, heat source/sink and chemical reaction. Copper oxide () and titanium oxide () are acknowledged as nanoparticle materials. The nondimensional governing equations were subjected to the Laplace transformation technique to derive closed-form solutions. Graphical representations are provided to analyze how changes in physical parameters, such as the magnetic field, heat radiation, heat source/sink and chemical reaction, affect the velocity, temperature… More >

  • Open Access

    ARTICLE

    Fatigue Crack Propagation Law of Corroded Steel Box Girders in Long Span Bridges

    Ying Wang1,*, Longxiao Chao1, Jun Chen2, Songbai Jiang1

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 201-227, 2024, DOI:10.32604/cmes.2024.046129

    Abstract In order to investigate the fatigue performance of orthotropic anisotropic steel bridge decks, this study realizes the simulation of the welding process through elastic-plastic finite element theory, thermal-structural sequential coupling, and the birth-death element method. The simulated welding residual stresses are introduced into the multiscale finite element model of the bridge as the initial stress. Furthermore, the study explores the impact of residual stress on crack propagation in the fatigue-vulnerable components of the corroded steel box girder. The results indicate that fatigue cracks at the weld toe of the top deck, the weld root of the top deck, and the… More > Graphic Abstract

    Fatigue Crack Propagation Law of Corroded Steel Box Girders in Long Span Bridges

  • Open Access

    ARTICLE

    Knockdown of circular RNA (CircRNA)_001896 inhibits cervical cancer proliferation and stemness in vivo and in vitro

    JIA SHAO1,2, CAN ZHANG2, YAONAN TANG2, AIQIN HE2, WEIPEI ZHU1,*

    BIOCELL, Vol.48, No.4, pp. 571-580, 2024, DOI:10.32604/biocell.2024.049092

    Abstract Objective: Previous studies indicated that aberrant circular RNA (circRNA) expression affects gene expression regulatory networks, leading to the aberrant activation of tumor pathways and promoting tumor cell growth. However, the expression, clinical significance, and effects on cell propagation, invasion, and dissemination of circRNA_001896 in cervical cancer (CC) tissues remain unclear. Methods: The Gene Expression Omnibus (GEO) datasets (GSE113696 and GSE102686) were used to examine differential circRNA expression in CC and adjacent tissues. The expression of circRNA_001896 was detected in 72 CC patients using fluorescence quantitative PCR. Correlation analysis with clinical pathological features was performed through COX multivariate and univariate analysis.… More >

  • Open Access

    REVIEW

    Therapeutic and regenerative potential of different sources of mesenchymal stem cells for cardiovascular diseases

    YARA ALZGHOUL, HALA J. BANI ISSA, AHMAD K. SANAJLEH, TAQWA ALABDUH, FATIMAH RABABAH, MAHA AL-SHDAIFAT, EJLAL ABU-EL-RUB*, FATIMAH ALMAHASNEH, RAMADA R. KHASAWNEH, AYMAN ALZU’BI, HUTHAIFA MAGABLEH

    BIOCELL, Vol.48, No.4, pp. 559-569, 2024, DOI:10.32604/biocell.2024.048056

    Abstract Mesenchymal stem cells (MSCs) are ideal candidates for treating many cardiovascular diseases. MSCs can modify the internal cardiac microenvironment to facilitate their immunomodulatory and differentiation abilities, which are essential to restore heart function. MSCs can be easily isolated from different sources, including bone marrow, adipose tissues, umbilical cord, and dental pulp. MSCs from various sources differ in their regenerative and therapeutic abilities for cardiovascular disorders. In this review, we will summarize the therapeutic potential of each MSC source for heart diseases and highlight the possible molecular mechanisms of each source to restore cardiac function. More >

  • Open Access

    REVIEW

    Do tensile and shear forces exerted on cells influence mechanotransduction through stored energy considerations?

    FREDERICK H. SILVER1,2,*, TANMAY DESHMUKH2

    BIOCELL, Vol.48, No.4, pp. 525-540, 2024, DOI:10.32604/biocell.2024.047965

    Abstract All tissues in the body are subjected externally to gravity and internally by collagen fibril and cellular retractive forces that create stress and energy equilibrium required for homeostasis. Mechanotransduction involves mechanical work (force through a distance) and energy storage as kinetic and potential energy. This leads to changes in cell mitosis or apoptosis and the synthesis or loss of tissue components. It involves the application of energy directly to cells through integrin-mediated processes, cell-cell connections, stretching of the cell cytoplasm, and activation of the cell nucleus via yes-associated protein (YAP) and transcriptional coactivator with PDZ-motif (TAZ). These processes involve numerous… More >

  • Open Access

    ARTICLE

    Bronchoalveolar lavage fluid metagenomic next-generation sequencing assay for identifying pathogens in lung cancer patients

    JIYU WANG1,2, HUIXIA LI1,2, DEYUAN ZHOU1,2, LIHONG BAI1,2, KEJING TANG1,2,3,*

    BIOCELL, Vol.48, No.4, pp. 623-637, 2024, DOI:10.32604/biocell.2024.030420

    Abstract Background: For patients with lung cancer, timely identification of new lung lesions as infectious or non-infectious, and accurate identification of pathogens is very important in improving OS of patients. As a new auxiliary examination, metagenomic next-generation sequencing (mNGS) is believed to be more accurate in diagnosing infectious diseases in patients without underlying diseases, compared with conventional microbial tests (CMTs). We designed this study to find out whether mNGS has better performance in distinguishing infectious and non-infectious diseases in lung cancer patients using bronchoalveolar lavage fluid (BALF). Materials and Methods: This study was a real-world retrospective review based on electronic medical… More >

  • Open Access

    ARTICLE

    Securing Mobile Cloud-Based Electronic Health Records: A Blockchain-Powered Cryptographic Solution with Enhanced Privacy and Efficiency

    Umer Nauman1, Yuhong Zhang2, Zhihui Li3, Tong Zhen1,3,*

    Journal of Intelligent Medicine and Healthcare, Vol.2, pp. 15-34, 2024, DOI:10.32604/jimh.2024.048784

    Abstract The convergence of handheld devices and cloud-based computing has transformed how Electronic Health Records (EHRs) are stored in mobile cloud paradigms, offering benefits such as affordability, adaptability, and portability. However, it also introduces challenges regarding network security and data confidentiality, as it aims to exchange EHRs among mobile users while maintaining high levels of security. This study proposes an innovative blockchain-based solution to these issues and presents secure cloud storage for healthcare data. To provide enhanced cryptography, the proposed method combines an enhanced Blowfish encryption method with a new key generation technique called Elephant Herding Optimization with Resistance-Based Training (EHO-RBT).… More >

  • Open Access

    ARTICLE

    Comparative Analysis of Reaction to Fire and Flammability of Hemp Shives Insulation Boards with Incorporated Microencapsulated Phase Change Materials

    Inga Zotova1,*, Edgars Kirilovs1, Laura Ziemele2

    Journal of Renewable Materials, Vol.12, No.3, pp. 603-613, 2024, DOI:10.32604/jrm.2024.047607

    Abstract Nowadays buildings contain innovative materials, materials from local resources, production surpluses and rapidly renewable natural resources. Phase Change Materials (PCM) are one such group of novel materials which reduce building energy consumption. With the wider availability of microencapsulated PCM, there is an opportunity to develop a new type of insulating materials, combinate PCM with traditional insulation materials for latent heat energy storage. These materials are typically flammable and are located on the interior wall finishing yet there has been no detailed assessment of their fire performance. In this research work prototypes of low-density insulating boards for indoor spaces from hemp… More > Graphic Abstract

    Comparative Analysis of Reaction to Fire and Flammability of Hemp Shives Insulation Boards with Incorporated Microencapsulated Phase Change Materials

  • Open Access

    ARTICLE

    Bio-Based Rigid Polyurethane Foams for Cryogenic Insulation

    Laima Vevere*, Beatrise Sture, Vladimir Yakushin, Mikelis Kirpluks, Ugis Cabulis

    Journal of Renewable Materials, Vol.12, No.3, pp. 585-602, 2024, DOI:10.32604/jrm.2024.047350

    Abstract Cryogenic insulation material rigid polyurethane (PU) foams were developed using bio-based and recycled feedstock. Polyols obtained from tall oil fatty acids produced as a side stream of wood biomass pulping and recycled polyethylene terephthalate were used to develop rigid PU foam formulations. The 4th generation physical blowing agents with low global warming potential and low ozone depletion potential were used to develop rigid PU foam cryogenic insulation with excellent mechanical and thermal properties. Obtained rigid PU foams had a thermal conductivity coefficient as low as 0.0171 W/m·K and an apparent density of 37–40 kg/m3. The developed rigid PU foams had… More > Graphic Abstract

    Bio-Based Rigid Polyurethane Foams for Cryogenic Insulation

  • Open Access

    ARTICLE

    Dynamiques Spatio-Temporelles de l’Occupation des Terres dans les Zones de Production Cotonnière et Céréalière au Mali

    Moumouni Sidibé1,2,*, Augustin K. N. Aoudji1, Yaya Issifou Moumouni3,*, Issa Sacko4, Idelphonse Saliou1, Bourema Koné2, Achille Ephrem Assogbadjo5, Afio Zannou1

    Revue Internationale de Géomatique, Vol.33, pp. 51-76, 2024, DOI:10.32604/rig.2024.045505

    Abstract La dynamique d’occupation des terres constitue un préalable pour l’identification des contraintes de gestion des ressources naturelles, l’évolution de pratiques agraires et la croissance démographique. L’objectif de cette recherche est d’améliorer les connaissances sur la dynamique d’occupation des terres agricoles dans les zones de cultures sèches (Cinzana) et cotonnière (Kléla) au Mali. La méthodologie utilisée a consisté à la collecte des données planimétriques et à l’analyse diachronique à travers des images satellitaires Landsat TM (Thematic Mapper) de 2000 et OLI (Operational Land Image) de 2020. Les taux de dégradation et de déforestation des formations naturelles ont été calculés d’une part… More > Graphic Abstract

    Dynamiques Spatio-Temporelles de l’Occupation des Terres dans les Zones de Production Cotonnière et Céréalière au Mali

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