ALEX A. FRANCOEUR^*, NATALIE AYOUB, DANIELLE GREENBERG, KRISHNANSU S. TEWARI

Oncology Research, Vol.33, No.7, pp. 1511-1530, 2025, DOI:10.32604/or.2025.061120 - 26 June 2025

Abstract Endometrial cancer is the most common gynecologic cancer diagnosed in the United States and mortality is on the rise. Advanced and recurrent endometrial cancer represents a treatment challenge as historically there have been limited therapeutic options for patients. In the last several years, multiple practice-changing clinical trials have led to significant improvements in the treatment landscape. This review will cover updates in the treatment and management of advanced and recurrent endometrial cancer with a focus on novel therapeutics, such as anti-PD-L1 and PD-1 inhibitors, poly ADP-ribose polymerase (PARP) inhibitors, antibody-drug conjugates, and hormonal therapy. More >

Tehreem Fatima¹, Kewen Xia^1,*, Wenbiao Yang², Qurat Ul Ain¹, Poornima Lankani Perera¹

CMC-Computers, Materials & Continua, Vol.84, No.1, pp. 811-826, 2025, DOI:10.32604/cmc.2025.063686 - 09 June 2025

Abstract The rising prevalence of diabetes in modern society underscores the urgent need for precise and efficient diagnostic tools to support early intervention and treatment. However, the inherent limitations of existing datasets, including significant class imbalances and inadequate sample diversity, pose challenges to the accurate prediction and classification of diabetes. Addressing these issues, this study proposes an innovative diabetes prediction framework that integrates a hybrid Convolutional Neural Network-Bidirectional Gated Recurrent Unit (CNN-BiGRU) model for classification with Adaptive Synthetic Sampling (ADASYN) for data augmentation. ADASYN was employed to generate synthetic yet representative data samples, effectively mitigating class… More >

Sahbi Boubaker^1,*, Adel Mellit^2,3,*, Nejib Ghazouani⁴, Walid Meskine⁵, Mohamed Benghanem⁶, Habib Kraiem^7,8

CMES-Computer Modeling in Engineering & Sciences, Vol.143, No.2, pp. 2237-2259, 2025, DOI:10.32604/cmes.2025.064530 - 30 May 2025

Abstract Electric vehicles (EVs) are gradually being deployed in the transportation sector. Although they have a high impact on reducing greenhouse gas emissions, their penetration is challenged by their random energy demand and difficult scheduling of their optimal charging. To cope with these problems, this paper presents a novel approach for photovoltaic grid-connected microgrid EV charging station energy demand forecasting. The present study is part of a comprehensive framework involving emerging technologies such as drones and artificial intelligence designed to support the EVs’ charging scheduling task. By using predictive algorithms for solar generation and load demand… More >

Wonbyung Lee, Jang Hyun Kim^*

CMC-Computers, Materials & Continua, Vol.83, No.3, pp. 5393-5412, 2025, DOI:10.32604/cmc.2025.065413 - 19 May 2025

Abstract Predicting player performance in sports is a critical challenge with significant implications for team success, fan engagement, and financial outcomes. Although, in Major League Baseball (MLB), statistical methodologies such as sabermetrics have been widely used, the dynamic nature of sports makes accurate performance prediction a difficult task. Enhanced forecasts can provide immense value to team managers by aiding strategic player contract and acquisition decisions. This study addresses this challenge by employing the temporal fusion transformer (TFT), an advanced and cutting-edge deep learning model for complex data, to predict pitchers’ earned run average (ERA), a key More >

Qian Zhu¹, Qian Kang¹, Tao Xu², Dengxiu Yu^3,*, Zhen Wang¹

CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 1855-1879, 2025, DOI:10.32604/cmc.2025.061913 - 16 April 2025

Abstract In this study, we present a deterministic convergence analysis of Gated Recurrent Unit (GRU) networks enhanced by a smoothing regularization technique. While GRU architectures effectively mitigate gradient vanishing/exploding issues in sequential modeling, they remain prone to overfitting, particularly under noisy or limited training data. Traditional regularization, despite enforcing sparsity and accelerating optimization, introduces non-differentiable points in the error function, leading to oscillations during training. To address this, we propose a novel smoothing regularization framework that replaces the non-differentiable absolute function with a quadratic approximation, ensuring gradient continuity and stabilizing the optimization landscape. Theoretically, we rigorously… More >

Nanjiang Zhong^*, Xinchen Jiang, Yuan Yao

CMC-Computers, Materials & Continua, Vol.82, No.3, pp. 4741-4757, 2025, DOI:10.32604/cmc.2025.059536 - 06 March 2025

Abstract The proliferation of rumors on social media has caused serious harm to society. Although previous research has attempted to use deep learning methods for rumor detection, they did not simultaneously consider the two key features of temporal and spatial domains. More importantly, these methods struggle to automatically generate convincing explanations for the detection results, which is crucial for preventing the further spread of rumors. To address these limitations, this paper proposes a novel method that integrates both temporal and spatial features while leveraging Large Language Models (LLMs) to automatically generate explanations for the detection results.… More >

Ruoxin Li^1,*, Shaoxiong Wu¹, Fengping Deng¹, Zhongli Tian¹, Hua Cai¹, Xiang Li¹, Xu Xu¹, Qi Liu^2,3

CMC-Computers, Materials & Continua, Vol.82, No.2, pp. 2969-2984, 2025, DOI:10.32604/cmc.2025.060230 - 17 February 2025

Abstract Studies to enhance the management of electrical energy have gained considerable momentum in recent years. The question of how much energy will be needed in households is a pressing issue as it allows the management plan of the available resources at the power grids and consumer levels. A non-intrusive inference process can be adopted to predict the amount of energy required by appliances. In this study, an inference process of appliance consumption based on temporal and environmental factors used as a soft sensor is proposed. First, a study of the correlation between the electrical and… More >

Dalal AL-Alimi¹, Mohammed A. A. Al-qaness^2,3,*, Robertas Damaševičius^4,*

CMC-Computers, Materials & Continua, Vol.82, No.2, pp. 3539-3561, 2025, DOI:10.32604/cmc.2025.059869 - 17 February 2025

Abstract Accurate forecasting of oil production is essential for optimizing resource management and minimizing operational risks in the energy sector. Traditional time-series forecasting techniques, despite their widespread application, often encounter difficulties in handling the complexities of oil production data, which is characterized by non-linear patterns, skewed distributions, and the presence of outliers. To overcome these limitations, deep learning methods have emerged as more robust alternatives. However, while deep neural networks offer improved accuracy, they demand substantial amounts of data for effective training. Conversely, shallow networks with fewer layers lack the capacity to model complex data distributions… More >

Buchi Reddy Ramakantha Reddy, Ramasamy Lokesh Kumar^*

CMC-Computers, Materials & Continua, Vol.81, No.3, pp. 4081-4107, 2024, DOI:10.32604/cmc.2024.057071 - 19 December 2024

Abstract Traditional e-commerce recommendation systems often struggle with dynamic user preferences and a vast array of products, leading to suboptimal user experiences. To address this, our study presents a Personalized Adaptive Multi-Product Recommendation System (PAMR) leveraging transfer learning and Bi-GRU (Bidirectional Gated Recurrent Units). Using a large dataset of user reviews from Amazon and Flipkart, we employ transfer learning with pre-trained models (AlexNet, GoogleNet, ResNet-50) to extract high-level attributes from product data, ensuring effective feature representation even with limited data. Bi-GRU captures both spatial and sequential dependencies in user-item interactions. The innovation of this study lies… More >

Israa Ibraheem Al Barazanchi^1,2,*, Wahidah Hashim¹, Reema Thabit¹, Mashary Nawwaf Alrasheedy^3,4, Abeer Aljohan⁵, Jongwoon Park⁶, Byoungchol Chang⁶

CMC-Computers, Materials & Continua, Vol.81, No.3, pp. 4787-4832, 2024, DOI:10.32604/cmc.2024.055079 - 19 December 2024

Abstract This research aims to enhance Clinical Decision Support Systems (CDSS) within Wireless Body Area Networks (WBANs) by leveraging advanced machine learning techniques. Specifically, we target the challenges of accurate diagnosis in medical imaging and sequential data analysis using Recurrent Neural Networks (RNNs) with Long Short-Term Memory (LSTM) layers and echo state cells. These models are tailored to improve diagnostic precision, particularly for conditions like rotator cuff tears in osteoporosis patients and gastrointestinal diseases. Traditional diagnostic methods and existing CDSS frameworks often fall short in managing complex, sequential medical data, struggling with long-term dependencies and data… More >