Claudia G. REIDES^1,2, Romina M. LASAGNI VITAR^1,2, Agustina PEVERINI¹, Natasha S. JANEZIC¹, Ailen G. HVOZDA ARANA¹, Sandra M. FERREIRA^1,2, Susana F. LLESUY^1,2*

BIOCELL, Vol.40, No.1, pp. 51-54, 2016, DOI:10.32604/biocell.2016.40.051

Abstract The purpose of this study was to evaluate the redox status changes of primary visual targets in the rat brain of a high pressure-induced glaucoma model. The animal model consisted of inducing ocular hypertension by cauterizing two episcleral veins on the left eye. The markers of oxidative damage and the oxidative balance evaluated in the brain seven days postoperative were: nitrites concentration, levels of non-enzymatic antioxidants and antioxidant enzymes activity.
The increase in the nitrite content, which could be the result of the enhancement in the production of nitrogen species, and in the activity of NADPH oxidase in the glaucoma… More >

M.A. MONTENEGRO^*, M. SÁNCHEZ NEGRETTE^*, E.J. GIMENO^**, J.T. BORDA^*

BIOCELL, Vol.26, No.3, pp. 339-345, 2002, DOI:10.32604/biocell.2002.26.339

Abstract Wistar male rats, 3 months of age were given ad-libitum a nutritionally adequate diet and demineralized drinking water. The Molybdenum (Mo) and Tungsten (W) were provided in the drinking water at 200 ppm concentration. Intestinal tumors were induced by 1,2-dimethylhydrazine (DMH) given subcutaneously as 16 weekly doses at 20 mg/kg body weight. Mo in the form of (NH₄)₆ Mo₇O₂₄ 4H₂O or W in the form of (Na₂ WO₄) were provided in the drinking water two months before the first DMH treatment and were continued during 4 months more until the last DMH treatment. Three months after the last carcinogen injection,… More >

GLADYS N. HERMIDA, ALEJANDRO FARÍAS, LUISA E. FIORITO

BIOCELL, Vol.26, No.3, pp. 347-355, 2002, DOI:10.32604/biocell.2002.26.347

Abstract The lung of the toad, Melanophryniscus stelzneri stelzneri was studied using scanning and transmission electron microscopy. In M.s.stelzneri the parenchyma forms a polygonal network arrangement, therefore the parenchyma is edicular. These spaces are delimited by the interconnection of third order septa which are covered by respiratory epithelium. Small patches of ciliated epithelium without goblet cells appear irregularly distributed on the septa. The respiratory epithelium consists of one type of pneumocyte, which shows characteristics of both type I and type II alveolar cells of higher vertebrates. The pneumocytes are irregular in shape and possess attenuated cytoplasmic processes, which spread around the… More >

Virginia VANASCO, Timoteo MARCHINI, Natalia MAGNANI, Tamara VICO, Mariana GARCES, Lourdes CACERES, Alejandro GUAGLIANONE, Pablo EVELSON, Silvia ALVAREZ.^*

BIOCELL, Vol.40, No.1, pp. 47-50, 2016, DOI:10.32604/biocell.2016.40.047

Abstract Several authors have addressed the importance of mitochondrial function in inflammatory syndromes, as it may play a role in the genesis of tissue injury. Sepsis and exposition to environmental particles are examples of inflammatory conditions. Sepsis occurs with an exacerbated inflammatory response that damages tissue mitochondria and impairs bioenergetic processes. One of the current hypotheses for the molecular mechanisms underlying the complex condition of sepsis is that enhanced NO production and oxidative stress lead to mitochondrial dysfunction, bioenergetic derangement and organ failure. The mechanism of particulate matter-health effects are believed to involve inflammation and oxidative stress. Components in particles that… More >

ESSI KESKINEN¹ , YASUHARU TAKAKU² , V. BENNO MEYER-ROCHOW³, TAKAHIKO HARIYAMA⁴

BIOCELL, Vol.26, No.3, pp. 357-367, 2002, DOI:10.32604/biocell.2002.26.357

Abstract The aims of this paper have been (a) to characterize marginal ommatidia from different eye regions through a detailed description of their distinct ultrastructural features in three different size-classes of L. exotica, and (b) to compare microanatomical characteristics of the marginal ommatidia with those of ommatidia of the same eye, but located further centrally. On the basis of transverse as well as longitudinal sections we conclude that new ommatidia are added from a crescentic dorso-anterio-ventral edge of the eye and that maturing ommatidia go through a sequence in which originally the nuclei of cone -, pigment-, and retinula cells are… More >

A. VIGLIOCCO^*, B. BONAMICO^*, S. ALEMANO^*, O. MIERSCH^**, G. ABDALA^*

BIOCELL, Vol.26, No.3, pp. 369-374, 2002, DOI:10.32604/biocell.2002.26.369

Abstract In the present paper we study the possible biological relevance of endogenous jasmonic acid (JA) and exogenous salicylic acid (SA) in a plant-microbial system maize-virus. The virus disease "Mal de Río Cuarto" is caused by the maize rough dwarf virus - Río Cuarto. The characteristic symptoms are the appearance of galls or "enations" in leaves, shortening of the stem internodes, poor radical system and general stunting. Changes in JA and protein pattern in maize control and infected plants of a virus-tolerant cultivar were investigated. Healthy and infected-leaf discs were collected for JA measurement at different post-infection times (20, 40, 60… More >

Natacha E PILONI, Elizabeth ROBELLO, Julián G BONETTO, Susana PUNTARULO^*

BIOCELL, Vol.40, No.1, pp. 39-42, 2016, DOI:10.32604/biocell.2016.40.039

Abstract Fe is essential for human life because it constitutes the required cofactor for proteins of diverse biological functions. However, the development of oxidative stress by exposure to excessive Fe, share signaling pathways with other treatments including activation of redox-sensitive factors. This study was focused on the comparison on the effects of Fe in the brain and other organs in vivo. The oxidative effects triggered by Fe overload strongly depend not only on the administration protocol, but also on the Fe-compound used, and the studied organ. In both the liver and the brain, Fe content drastically increased after Fe-dextran administration. However,… More >

CHARLES GÉMINARD, AUDE DE GASSART, MICHEL VIDAL

BIOCELL, Vol.26, No.2, pp. 205-215, 2002, DOI:10.32604/biocell.2002.26.205

Abstract During the differentiation of erythroid cells, a vast program of maturation takes place, leading to decay or elimination of organelles, including the nucleus, mitochondria, ribosomes, lysosomes, endoplasmic reticulum and Golgi apparatus. During the last step of red cell maturation, remaining organelles, primarily mitochondria and ribosomes but also vestiges of others are finally cleared from the cell. This cleaning session also affects specific proteins that are partially or entirely removed from the cell surface. The interplay of the various events and their causal relationships are approached here. More >

MARIANA N. MELCHIORRE, HERNÁN R. LASCANO, VICTORIO S.TRIPPI

BIOCELL, Vol.26, No.2, pp. 217-223, 2002, DOI:10.32604/biocell.2002.26.217

Abstract Wheat (Triticum aestivum) transgenic plants of an important commercial cv (Oasis) was obtained with an efficient and short procedure. First, the optimum conditions for the embriogenic calli generation from inmature embryos with a high regeneration percentage were established. The transformation of calli was performed by high velocity microprojectile bombardment, using the pAHC25 plasmid, which contains the reporter gene β-glucuronidase (GUS) and the selectable BAR gene which confers resistance to the herbicide Basta. The transformations were confirmed by β-glucuronidase assay activity, PCR and Southern blot analysis. The efficiency of this procedure was high and similar to other reports in which “model”… More >

ALICIA I. WEYERS, LAURA I. UGNIA, HUGO GARCÍA OVANDO, NORA B. GORLA*

BIOCELL, Vol.26, No.2, pp. 225-228, 2002, DOI:10.32604/biocell.2002.26.225

Abstract Ciprofloxacin (CFX) is an effective and relatively safe antimicrobial used in a variety of human infections. However, adverse drug reactions and positive results in genotoxic tests are reported.
In order to understand the possible pathophysiological mechanisms of the toxic effects informed for CFX, lipid hydroperoxides (LOOH) -oxidative mediators of peroxidation- were quantified in liver and kidney of mice, after 15 to 360 minutes of the ciprofloxacin administration at doses of 10 mg/ Kg or 100 mg/ Kg by ip route. The peroxidation in the lipid fraction was evaluated by measuring the amount of hydroperoxides through the oxidation of 1-… More >