Hongyu Mu^1,2,*, Yinyan Wang¹, Hong Teng², Xingtian Zhao², Xiaolong Zhang², Yan Jin², Shiyang Hao², Jingfeng Zhao²

Energy Engineering, Vol.119, No.3, pp. 1103-1116, 2022, DOI:10.32604/ee.2022.017273

Abstract The aerodynamics and heat transfer performance in the rear-mounted automobile cabin have an important influence on the engine's safety and the operational stability of the automobile. The article uses STAR-CCM and GT-COOL software to establish the 3D wind tunnel model and engine cooling system model of the internal combustion engine. At the same time, we established a 3D artificial coupling model through parameter transfer. The research results show that the heat transfer coefficient decreases with the increase of the comprehensive drag coefficient of the nacelle. This shows that the cabin flow field has an important influence on the heat transfer… More >

Hui Wang, Yishu Chen^*, Zichao Wu, Haocheng Xu

Energy Engineering, Vol.119, No.3, pp. 1141-1167, 2022, DOI:10.32604/ee.2022.016151

Abstract

The randomness and uncertainty of renewable energy generation are expected to significantly change the optimal decision-making of trans-provincial electricity market subjects. Therefore, it is beneficial to optimize the interests of each of these subjects, considering the unpredictable risks of renewable energy under the renewable portfolio standards (RPS) and researching their effects on the optimal decision-making of trans-provincial electricity market multi-subjects. First, we develop a trans-provincial trading market mechanism for renewable energy and clarify the electricity supply and demand relation and the green certificates supply and demand relation of trans-provincial electricity market multi-subjects. Then, under the RPS, we construct a multi-subject… More >

Xueqin Tian¹, Mengran Cui², Tong Xu¹, Jinfei Sun², Xinlei Wang¹, Jiangxiang Guo², De-Gejirifu^1,*, Na Wang¹

Energy Engineering, Vol.119, No.3, pp. 1031-1045, 2022, DOI:10.32604/ee.2022.015984

Abstract A modeling method of regional integrated energy system based on bus method and transient simulation is proposed, and the system optimization is based on the dynamic balance of supply and demand in the whole year energy supply cycle. A CCHP system of gas turbine coupled with ground source heat pump and electric refrigeration unit is constructed. The energy relationship of the system is described by bus structure, and the transient calculation model is built on TRNSYS platform. The weighted sum of annual total cost saving rate, primary energy saving rate and environmental pollutant shadow cost saving rate is taken as… More >

Shuqiao Dan^*

Energy Engineering, Vol.119, No.3, pp. 1047-1057, 2022, DOI:10.32604/ee.2022.015594

Abstract There are several problems existing in the direct starting of asynchronous motor such as large starting current, reactive power absorption from network side and weak interference-resistance, etc. Aiming at this, a comprehensive energy-saving optimization model of asynchronous motor for voltage regulation based on static synchronous compensator (STATCOM) is put forward. By analyzing the working principle and operation performance of static synchronous compensator regulating voltage, a new energy-efficient optimization method for asynchronous motor is proposed based on the voltage regulator model to achieve soft start, continuous dynamic reactive power compensation and the terminal voltage stability control. The multi-objective optimal operation of… More >

Guofeng Liu^*, Can Zhang, Zhengyi Zhu, Xuyan Wang

Energy Engineering, Vol.119, No.3, pp. 929-946, 2022, DOI:10.32604/ee.2022.014816

Abstract Due to the increasing power consumption of whole society and widely using of new non-linear and asymmetric electrical equipment, power quality assessment problem in the new period has attracted more and more attention. The mathematical essence of comprehensive assessment of power quality is a multi-attribute optimal decision-making problem. In order to solve the key problem of determining the indicator weight in the process of power quality assessment, a rough analytic hierarchy process (AHP) is proposed to aggregate the judgment opinions of multiple experts and eliminate the subjective effects of single expert judgment. Based on the advantage of extension analysis for… More >

Hao Luo^1,#,*, Yanjie Ji^2,#, Xinrong Gao¹, Xinying Liu¹, Yunzhao Wu³, Yingli Wu^3,*

Oncologie, Vol.24, No.1, pp. 85-99, 2022, DOI:10.32604/oncologie.2022.021705

Abstract The ubiquitin-proteasome system (UPS) is an important pathway for cellular protein degradation. The components of this pathway, including the proteasome, ubiquitinase, and deubiquitinase, are highly specialized and strictly regulated. The ubiquitin-specific protease 2 (USP2) belongs to the ubiquitin-specific proteases, a subgroup of deubiquitinating enzymes. USP2 plays essential roles in regulating cell survival, cell cycle, circadian rhythm, cell metabolism, inflammatory response, antiviral response, and metastasis by interacting with certain proteins such as Cyclin D1, PER1, CRY1, HDM2/p53, FASN, LDLR, TRAF6, TBK1, and TGFBR1-TGFBR2 complex. Elevation of USP2 has been observed in a variety of cancers, including glioma, testicular cancer, breast cancer,… More >

Dong Yan^1,#, Chunxiao Li^2,#, Yantong Zhou², Xue Yan¹, Weihua Zhi¹, Haili Qian^2,*, Yue Han^1,*

Oncologie, Vol.24, No.1, pp. 101-111, 2022, DOI:10.32604/oncologie.2022.020357

Abstract Hepatocellular carcinoma (HCC) is one of the most deadly types of cancer. Sorafenib is currently the only available first-line molecular targeted drug approved by the FDA for HCC. However, primary and secondary resistance is often encountered with treatment with sorafenib. Genomic alterations found in HCC represent potential targets to develop new drugs or new combinational strategies against this type of cancer. Here we analyzed genomic alterations from the TCGA database of HCC samples and the corresponding targeted drugs available to the clinic to identify candidate drugs that might hold promise when used in combination with sorafenib. Our results revealed that… More >

Beifen Dai^1,#, Zhihao Xu^2,#, Hongjue Li³, Bo Wang³, Jinsong Cai¹, Xiaomo Liu^4,*

Oncologie, Vol.24, No.1, pp. 113-130, 2022, DOI:10.32604/oncologie.2022.020259

Abstract Large-scale genomic studies are important ways to comprehensively decode the human genomics, and provide valuable insights to human disease causalities and phenotype developments. Genomic studies are in need of high throughput bioinformatics analyses to harness and integrate such big data. It is in this overarching context that artificial intelligence (AI) offers enormous potentials to advance genomic studies. However, racial bias is always an important issue in the data. It is usually due to the accumulation process of the dataset that inevitability involved diverse subjects with different races. How can race bias affect the outcomes of AI methods? In this work,… More >

Jiayi Huang¹, Xue Bai¹, Xiaofeng Xie¹, Liping Chen¹, Xiaofeng Lan¹, Qiuyi Zhang¹, Lin Song¹, Pengjiao Hong^2,3, Caiwen Du^1,*

Oncologie, Vol.24, No.1, pp. 131-145, 2022, DOI:10.32604/oncologie.2022.019881

Abstract Background: Vinorelbine can be used to treat metastatic breast cancer as a single agent or in combination with other chemotherapy agents, although there is little real-world data for its use, particularly the oral form, in China. The current study aimed to explore the efficacy and safety of oral vinorelbine in patients with metastatic breast cancer in real-world clinical practice. Methods: A total of 194 patients with metastatic breast cancer received oral vinorelbine as a treatment between February 2017 and January 2021 at the National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences… More >

Federico Cappellacci^*, Gian Luigi Canu, Stefano Piras, Giacomo Anedda, Pietro Giorgio Calò, Fabio Medas

Oncologie, Vol.24, No.1, pp. 35-50, 2022, DOI:10.32604/oncologie.2022.020864

Abstract Thyroid cancer is the fifth most common cancer in the USA, with differentiated subtype accounting for more than 95% of neoplasm. Surgery remains the mainstay of treatment, either with lobectomy or total thyroidectomy. In the last decades, many technological innovations have been introduced in this field. The aim of this review is to illustrate the most recent advances regarding the classical surgical approach, particularly regarding hemostatic devices, parathyroid identification with fluorescence systems, intraoperative identification of lymph node metastases, and intraoperative neuromonitoring. More >