IVANA PAJIC-LIJAKOVIC^*, MILAN MILIVOJEVIC

BIOCELL, Vol.47, No.1, pp. 15-25, 2023, DOI:10.32604/biocell.2023.023469

Abstract A key feature that distinguishes cancer cells from all other cells is their capability to spread throughout the body. Although how cancer cells collectively migrate by following molecular rules which influence the state of cell-cell adhesion contacts has been comprehensively formulated, the impact of physical interactions on cell spreading remains less understood. Cumulative effects of physical interactions exist as the interplay between various physical parameters such as (1) tissue surface tension, (2) viscoelasticity caused by collective cell migration, and (3) solid stress accumulated in the cell aggregate core region. This review aims to point out the role of these physical… More >

Muzi Liao^1,2,#, Hui Tong^1,2,#, Xiangya Huang^1,2, Fang Liu³, Jingwei He^3,*, Sui Mai^1,2,*

Journal of Renewable Materials, Vol.10, No.12, pp. 3201-3215, 2022, DOI:10.32604/jrm.2022.022090

Abstract Novel branched silicone methacrylate was developed. The mechanical and biological properties of the resin system were investigated to select the formula proportion with the best overall performance. The novel silicone-containing monomers were combined with an incremental sequence of glass filler concentrations in commonly used Bis-GMA/TEGDMA (50/50, wt./wt.) dental resin systems. Physicochemical properties, surface properties, antibacterial adhesion effect, anti-biofilm effect, protein adsorption, and cytotoxicity were evaluated. The results showed that BSMs did not affect the double bond conversion of dental resin, but could reduce volumetric shrinkage (p < 0.05). The BSM containing resins can resist protein and bacteria adhesion (S. Mutans)… More >

CLAUDE VERDIER^*

BIOCELL, Vol.46, No.11, pp. 2381-2386, 2022, DOI:10.32604/biocell.2022.021368

Abstract Cancer metastasis is still a major social issue with limited knowledge of the formation of tumors and their growth. In addition the formation of metastases is very difficult to understand, since it involves very complex physical mechanisms such as cellular interactions and cell rheology, which are flow-dependent. Previous studies investigated transendothelial migration using sophisticated techniques such as microfluidics, traction force microscopy (TFM) or Atomic Force Microscopy (AFM), combined with physical modeling. Here we summarize recent results and suggest new ways to investigate the precise mechanisms used by cancer cells to undergo transendothelial migration. More >

Daša Krapež Tomec, Angela Balzano, Jure Žigon, Milan Šernek, Mirko Kariž^*

Journal of Renewable Materials, Vol.10, No.7, pp. 1787-1796, 2022, DOI: 10.32604/jrm.2022.019760

Abstract As additive manufacturing technologies advance, new opportunities are opening up for their application in the furniture industry. Wood remains one of the leading raw materials in the furniture industry; therefore, possible options for combining it with 3D printing have been researched. The bonding of 3D-printed polymer parts with wood or 3D printing with wood-plastic composites is already known, but in our research we attempted to directly 3D print polylactic acid (PLA) on wood surfaces. The effect of printing parameters, as well as the surface preparation of wood on the shear strength of the bond between wood and on-printed material was… More >

RAFAEL SCAF DE MOLON^1,2, MARTA MARIA ALVES PEREIRA², ERICA DORIGATTI DE AVILA²

BIOCELL, Vol.46, No.5, pp. 1151-1156, 2022, DOI:10.32604/biocell.2022.018026

Abstract It has been recognized that physical and chemical properties of biomaterial surfaces mediate the quality of extracellular matrix (ECM) that may affect cell behaviors. In nature, ECM is a heterogeneous three-dimensional superstructure formed by three major components, glycosaminoglycan, glycoconjugate, and protein, that anchors cellular compartments in tissues and regulates the function and the behavior of cells. Changes in the biointerface alter the quality of ECM and morphology through cell surface receptors, which, in turn, enable it to trigger specific cell signaling and different cellular responses. In fact, a number of strategies have been used to improve the functionality of surfaces… More >

CLAIRE ELIZABETH HILLS, ELEFTHERIOS SIAMANTOURAS, PAUL EDWARD SQUIRES^*

BIOCELL, Vol.46, No.4, pp. 937-940, 2022, DOI:10.32604/biocell.2022.018414

Abstract Changes in cell-cell and cell-substrate adhesion markers are increasingly used to characterize disease onset and progression. However, these relationships depend on both the biochemical and molecular association between cells and between cells and their extracellular matrix, as well as the biophysical and mechanical properties orchestrated by cytoskeletal, membrane and matrix components. To fully appreciate the role of cell adhesion when determining normal physiology and the impact of disease on cellular function, it is important to consider both biochemical and biophysical attributes of the system being investigated. In this short viewpoint we reflect on our experiences assessing cell-cell and/or cell-matrix interactions… More >

RAFAEL MORENO-GÓMEZ-TOLEDANO^1,*, MARíA I. ARENAS², ESPERANZA VÉLEZ-VÉLEZ³, RICARDO J. BOSCH¹

BIOCELL, Vol.46, No.2, pp. 305-308, 2022, DOI:10.32604/biocell.2022.017894

Abstract Bisphenol A (BPA) is a xenoestrogen known for its implications for the endocrine systems and several other organs, including the kidneys. Recent renal studies have shown that BPA can induce alterations of the cytoskeleton and cell adhesion mechanisms such as a podocytopathy with proteinuria and hypertension, alterations involved in the progression of renal diseases. These data and the fact that BPA is known to be present in the urine of almost the entire population strongly suggest the critical need to reevaluate BPA exposures considered safe. More >

Çağrı Öner^1,* and Ertuğrul Çolak²

Oncologie, Vol.23, No.3, pp. 393-407, 2021, DOI:10.32604/Oncologie.2021.016958

Abstract piRNAs are novel members of small non-coding RNAs and have an impact on genetic and epigenetic mechanisms of cells. It was aimed to investigate the role of piR-651 on MCF-7 benign breast cancer cells by focusing on molecular characteristics. Anti-piR-651 was transfected and effects of piR-651 on proliferation, adhesion, and motility of MCF-7 cells were detected after the 24th, 48th, and 72nd hour. Gene expressions of piR-651, Ki-67, MMP-2, ERα, HIF-1α, and hTERT were determined by using RT-PCR. piR-651 inhibition caused the decrease of proliferation, adhesion (p < 0.001), and motility of MCF-7 cells. The efficiency of anti-piR-651 transfection supported… More >

LORENZO ALIBARDI¹, BERND NOECKER²

BIOCELL, Vol.45, No.4, pp. 1013-1022, 2021, DOI:10.32604/biocell.2021.013913

Abstract The differentiation of cells composing mature human hairs produces layers with different corneous characteristics that would tend to flake away one from another, as in the corneous layer of the epidermis, without anchoring junctions. It is likely that cell junctions established in the forming cells of the hair bulb are not completely degraded like in the corneous layer of the epidermis but instead remain in the hair shaft to bind mature cuticle, cortex, and medulla cells into a compact hair shaft. During cell differentiation in hairs, cell junctions seem to disappear, and little is known about the fate of junctional… More >

Yongping Yu¹, Lihui Chen¹, Juanjuan Wang¹, Guoji Liu^2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.125, No.2, pp. 647-670, 2020, DOI:10.32604/cmes.2020.011067

Abstract The tower line system will be in an unsafe status due to uniform or uneven fall of ice coating which is attached to the surface of tower and lines. The fall of ice could be caused by wind action or thermal force. In order to study the dynamic characteristics of the self-failure of the transmission line under the action of dynamic wind load, a finite element model of the two-span transmission tower line system was established. The birth and death element methods are used to simulate the icing and shedding of the line. Tensile failure strength is the shedding criterion… More >