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  • Open Access

    LETTER

    Hybrid Procedure for Interruption of Aortic Arch Associated with Bicuspid Aortic Valve Stenosis in an Infant

    Jiajun Xu1,#, Zhuo Shi2,#, Shanshan Shi1,*, Xiangming Fan2,*

    Congenital Heart Disease, Vol.19, No.5, pp. 535-540, 2024, DOI:10.32604/chd.2024.057558 - 31 December 2024

    Abstract Interrupted Aortic Arch (IAA) combined with aortic stenosis (AS) is a rare and complex congenital cardiac anomaly that presents significant challenges in clinical management. In this letter, we aim to share our experience in performing hybrid procedures on an infant diagnosed with IAA combined with bicuspid AS. This child exhibited significant recovery during follow-up. More >

  • Open Access

    ARTICLE

    Cardiac Rehabilitation by Pulmonary Artery Banding after Induced Dilated Cardiomyopathy: A Pilot Study on a Rodent Model

    Domenico Crea1, Arben Dedja1, Matteo Ponzoni1,2, Stefania Rizzo3, Alberto Cipriani4, Riccardo Bariani4, Kalliopi Pilichou3, Maria Bueno Marinas3, Danila Azzolina5, Massimo A. Padalino1,6,*

    Congenital Heart Disease, Vol.19, No.5, pp. 473-487, 2024, DOI:10.32604/chd.2025.057014 - 31 December 2024

    Abstract Background: Since 2015, the pulmonary artery banding (PAB), following the Giessen protocol, has treated end-stage heart failure in selected infants with preserved right ventricular function, acting as a bridge to transplant or recovery, as a result of ventricular-ventricular interaction. Objectives: To elucidate whether PAB is a feasible and reproducible procedure in a rodent model of pharmacologically induced dilated cardiomyopathy (DCM) and to evaluate PAB-induced ventricular rehabilitation. Methods: We used 49 Sprague-Dawley rats divided into four groups: a sham surgery control group, a healthy animal group undergoing PAB, a doxorubicin (DOX)- treated control group, and a DOX… More >

  • Open Access

    PROCEEDINGS

    Effects of Spin Excitation on the Dislocation Dynamics in Body-Centered Cubic Iron

    Hideki Mori1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.32, No.1, pp. 1-1, 2024, DOI:10.32604/icces.2024.012935

    Abstract To design the mechanical strength of iron, it is very important to clarify the detail of dislocation dynamics in Body-Centered Cubic (BCC) Iron. The dislocation core structures are typically confined to the nanometer scale.
    This implies that the resistance force from discrete atomic columns has a direct bearing on dislocation mobility.
    Recently, we've developed a high-fidelity inter-atomic potential leveraging neural networks built upon density functional theory (DFT) data. By conducting dislocation dynamics simulations, we've addressed shortcomings inherent in classical inter-atomic potential approaches. Nonetheless, a significant challenge persists: a three- to four-fold deviation exists between More >

  • Open Access

    PROCEEDINGS

    Theoretical Study on Hydrogen Diffusion Influenced Screw Dislocation Motion in Body-Centered Cubic Iron

    Jiaqin Xu1, Shuhei Shinzato1, Shihao Zhang1, Fan-Shun Meng1, Shigenobu Ogata1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.1, pp. 1-2, 2024, DOI:10.32604/icces.2024.011814

    Abstract Hydrogen has the potential to be the clean energy solution to achieve the sustainable development goals (SDGs). However, from preparation to utilization, the hydrogen embrittlement can not be neglected. Hydrogen embrittlement occurs as a result of hydrogen affecting dislocations motion and cracks opening. Dislocation motion in hydrogen environment has not been clarified although several mechanisms have been proposed, including the hydrogen enhanced decohesion (HEDE), the hydrogen enhanced macroscopic ductility (HEMP), the hydrogen enhanced local plastic model (HELP), etc. It is essential to comprehend the underlying hydrogen-dislocation interactions that cause embrittlement. Also, dynamics of dislocation motion… More >

  • Open Access

    ARTICLE

    An Expert System to Detect Political Arabic Articles Orientation Using CatBoost Classifier Boosted by Multi-Level Features

    Saad M. Darwish1,*, Abdul Rahman M. Sabri2, Dhafar Hamed Abd2, Adel A. Elzoghabi1

    Computer Systems Science and Engineering, Vol.48, No.6, pp. 1595-1624, 2024, DOI:10.32604/csse.2024.054615 - 22 November 2024

    Abstract The number of blogs and other forms of opinionated online content has increased dramatically in recent years. Many fields, including academia and national security, place an emphasis on automated political article orientation detection. Political articles (especially in the Arab world) are different from other articles due to their subjectivity, in which the author’s beliefs and political affiliation might have a significant influence on a political article. With categories representing the main political ideologies, this problem may be thought of as a subset of the text categorization (classification). In general, the performance of machine learning models… More >

  • Open Access

    ARTICLE

    The superiority of PMFs on reversing drug resistance of colon cancer and the effect on aerobic glycolysis-ROS-autophagy signaling axis

    YUQIN YIN1,2,#, YU WU1,#, HONGLIANG HUANG1,2, YINGYING DUAN1,2, ZHONGWEN YUAN1,2, LIHUI CAO1,2, JINJIN YING1,2, YONGHENG ZHOU3,*, SENLING FENG1,2,*

    Oncology Research, Vol.32, No.12, pp. 1891-1902, 2024, DOI:10.32604/or.2024.048778 - 13 November 2024

    Abstract Background: Polymethoxylated flavones (PMFs) are compounds present in citrus peels and other Rutaceae plants, which exhibit diverse biological activities, including robust antitumor and antioxidant effects. However, the mechanism of PMFs in reversing drug resistance to colon cancer remains unknown. In the present study, we aimed to investigate the potential connection between the aerobic glycolysis-ROS-autophagy signaling axis and the reversal of PTX resistance in colon cancer by PMFs. Methods: MTT Cell viability assay and colony formation assay were used to investigate the effect of PMFs combined with PTX in reversing HCT8/T cell resistance ex vivo; the mRNA… More > Graphic Abstract

    The superiority of PMFs on reversing drug resistance of colon cancer and the effect on aerobic glycolysis-ROS-autophagy signaling axis

  • Open Access

    ARTICLE

    Arabic Dialect Identification in Social Media: A Comparative Study of Deep Learning and Transformer Approaches

    Enas Yahya Alqulaity1, Wael M.S. Yafooz1,*, Abdullah Alourani2, Ayman Jaradat3

    Intelligent Automation & Soft Computing, Vol.39, No.5, pp. 907-928, 2024, DOI:10.32604/iasc.2024.055470 - 31 October 2024

    Abstract Arabic dialect identification is essential in Natural Language Processing (NLP) and forms a critical component of applications such as machine translation, sentiment analysis, and cross-language text generation. The difficulties in differentiating between Arabic dialects have garnered more attention in the last 10 years, particularly in social media. These difficulties result from the overlapping vocabulary of the dialects, the fluidity of online language use, and the difficulties in telling apart dialects that are closely related. Managing dialects with limited resources and adjusting to the ever-changing linguistic trends on social media platforms present additional challenges. A strong… More >

  • Open Access

    PROCEEDINGS

    A Novel Damage Model for Face-Centered Cubic Crystal Materials Incorporating Microscopic Crystal Cleavage and Slip Failure Mechanisms

    Qianyu Xia1, Zhixin Zhan1,*, Weiping Hu1, Qingchun Meng1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.29, No.1, pp. 1-1, 2024, DOI:10.32604/icces.2024.011238

    Abstract The occurrence of crystal cleavage and slip at the microscopic level in single crystal materials serves as the fundamental underlying factors leading to their macroscopic failures. Therefore, investigating the failure mechanisms and damage processes at the scale of slip systems significantly enhances our comprehension of the degradation and failure patterns exhibited by crystal materials.
    In this study, based on the theory of crystal plasticity, we examine the effects of microscopic damage on the slip systems concerning the failure of face-centered cubic (FCC) crystal materials. Additionally, we develop a novel damage model for FCC crystal materials, incorporating… More >

  • Open Access

    ARTICLE

    Synthesis and Characterization of Chitosan/Guar Protein Blended New Membrane with Enhanced Properties for Potential Applications

    Anuraag Moturi, Dharmesh R. Chejara*

    Journal of Polymer Materials, Vol.41, No.3, pp. 179-190, 2024, DOI:10.32604/jpm.2024.055887 - 30 September 2024

    Abstract A chitosan and guar protein isolate blend conjugate (Ch/GPI-Glu) based membrane has been designed and studied for its possible interaction with this biopolymer mixture. The designed conjugate chitosan/guar protein isolate blended membrane was investigated for its structural features using Fourier Transform Infrared Spectroscopy (FTIR), Thermal Gravimetric Analysis (TGA), X-Ray Diffraction (XRD) and Scanning Electron Microscopy (SEM) analyses. IR Spectroscopic data suggested that chitosan and guar protein isolate contributed to a specific intermolecular interaction. The designed membrane was water-insoluble and it exhibited strong polymer–protein interaction. Further, the membrane was also found to have a smooth morphology More >

  • Open Access

    ARTICLE

    Enhancing Arabic Cyberbullying Detection with End-to-End Transformer Model

    Mohamed A. Mahdi1, Suliman Mohamed Fati2,*, Mohamed A.G. Hazber1, Shahanawaj Ahamad3, Sawsan A. Saad4

    CMES-Computer Modeling in Engineering & Sciences, Vol.141, No.2, pp. 1651-1671, 2024, DOI:10.32604/cmes.2024.052291 - 27 September 2024

    Abstract Cyberbullying, a critical concern for digital safety, necessitates effective linguistic analysis tools that can navigate the complexities of language use in online spaces. To tackle this challenge, our study introduces a new approach employing Bidirectional Encoder Representations from the Transformers (BERT) base model (cased), originally pretrained in English. This model is uniquely adapted to recognize the intricate nuances of Arabic online communication, a key aspect often overlooked in conventional cyberbullying detection methods. Our model is an end-to-end solution that has been fine-tuned on a diverse dataset of Arabic social media (SM) tweets showing a notable… More >

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