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  • Open Access

    ARTICLE

    Off-Design Performance of Gas Turbine Power Units with Alternative Load-Control Strategies

    Zhiqiang Pan1, Zhiwen Lin1, Kunle Fan2, Cheng Yang2,*, Xiaoqian Ma2

    Energy Engineering, Vol.118, No.1, pp. 119-141, 2021, DOI:10.32604/EE.2020.013585 - 17 November 2020

    Abstract Gas turbine power units, as an effective way to cope with the severe challenge of renewable energy accommodation in power grids, arouse the interest of power enterprises in the deep peak-load regulation performance. Two common alternative load-control strategies including constant turbine inlet temperature (TIT) and constant turbine exhaust temperature (TET) regulations were taken into consideration. To comparatively investigate the part-load performance under these strategies, both mathematical and physical models were set up successively to serve as a validation and complementary to each other. For the mathematical model of compressor with inlet guide vane (IGV), combustor… More >

  • Open Access

    ARTICLE

    A Smart Wellness Service Platform and Its Practical Implementation

    Umar Farooq1, Intae Ryoo2, Gon Khang1,*

    CMC-Computers, Materials & Continua, Vol.66, No.1, pp. 45-57, 2021, DOI:10.32604/cmc.2020.013035 - 30 October 2020

    Abstract Advances in the field of medical sciences and medical technology, and present-day challenges, such as an aging population, rising medical expenses, and lifestyle-related diseases, have collectively catalyzed a research ecosystem termed “smart wellness.” This article describes the establishment of a smart wellness service platform designed to empower individuals to create a sense of balance in their lives. Step-by-step details include service model, design, and architectural considerations. As a proof of concept, implementation details of a Health Improvement and Management Systems (HIMS) Hub, a Smart Wellness Service Platform deployed in six cities in South Korea, are More >

  • Open Access

    ORIGINAL ARTICLE

    Preconceptional immunization with an allergen inhibits offspring thymic Th17 cells maturation without influence on Th1 and Th2 cells

    Marília Garcia de Oliveira1, Fábio da Ressureição Sgnotto2, Thamires Rodrigues de Sousa1, Beatriz Oliveira Fagundes1, Alberto Joséda Silva Duarte1,3, Jefferson Russo Victor1,4

    European Cytokine Network, Vol.31, No.3, pp. 113-117, 2020, DOI:10.1684/ecn.2020.0452

    Abstract The mechanisms through which maternal immunization can modulate offspring thymic maturation of lymphocytes are not fully understood. Here, we aimed to evaluate whether maternal OVA-immunization can inhibit the maturation of Th17 cells on offspring thymus. C57BL/6 females were immunized with OVA in Alum or Alum alone and mated with normal WT males. Offspring thymus was evaluated at three or 20 days of age. The demonstration that maternal OVA-immunization can inhibit offspring allergy development validated our experimental protocol. First, we observed that maternal OVA-immunization can inhibit the expression of RORγt and IL-17 molecules on immature T More >

  • Open Access

    ARTICLE

    Swelling dynamics of Poly (N, N- Dimethylacrylamide - co- Crotonic acid) Hydrogel and Evaluation of its Potential for Controlled Release of Fertilizers

    FATMA LOUZRI, SADJIA BENNOUR

    Journal of Polymer Materials, Vol.37, No.1-2, pp. 55-76, 2020, DOI:10.32381/JPM.2020.37.1-2.5

    Abstract Poly(N,N-dimethymethylacrylamide -co-crotonic acid) (P(DMA-CAx)) hydrogels were prepared by free radical polymerization, using N,N- methylenebisacrylamide (NMBA) as cross-linking agent. The synthesized hydrogels were characterized by Fourier transform infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA). The effects of comonomer composition and pH of the medium on the swelling behavior of hydrogels were investigated. The obtained results showed that the swelling capabilities of hydrogels increased as crotonic acid content and pH increased. In order to evaluate the controlled release potential of the polymeric matrix, it was loaded with potassium nitrate and ammonium nitrate as fertilizers and the release More >

  • Open Access

    REVIEW

    A REVIEW ON EXERGY ANALYSIS OF NANOFLUID FLOW THROUGH SEVERAL CONDUITS

    Lohit Sharmaa , Sunil Kumara , Robin Thakura , Bhaskar Goela , Amar Raj Singh Suria , Sashank Thapaa , Nitin Kumara , Rajesh Maithanib , Anil Kumarb

    Frontiers in Heat and Mass Transfer, Vol.14, pp. 1-15, 2020, DOI:10.5098/hmt.14.30

    Abstract This article presents an extensive review on exergy analysis of nanofluid flow through heat exchanger channels. The improvement of exergy efficiency of nanofluid flow through heat exchanger are determined by the net impact of the relative variations in the thermophysical properties of the nanoparticle which are sensitive towards numerous parameters including size and shape, material and concentration as well as base fluid thermal properties. Exergy efficiency of nanofluids flowing through heat exchanger is greater as compare to simple conventional fluids. The augmentation of exergy efficiency in the nanofluid flow through heat exchangers can be achieved More >

  • Open Access

    ARTICLE

    EFFICIENCY CENTERED MAINTENANCE FOR PREHEAT TRAINS OF CRUDE OIL DISTILLATION UNITS

    Daniel Yabrudy Mercadoa,*, Juan Fajardo Cuadroa, Bienvenido Sarria Lópezb, Camilo Cardona Agudelob

    Frontiers in Heat and Mass Transfer, Vol.15, pp. 1-12, 2020, DOI:10.5098/hmt.15.25

    Abstract This paper presents the efficiency-centered maintenance method to plan the maintenance intervention of the heat exchangers of a preheat train, taking into account the economic-energy improvement and maintenance cost. An appropriate cleaning schedule is needed to preserve the key performance parameters (KPPs) throughout the operation, if possible, nearest to the design values. The results of this work show that it is possible to schedule maintenance activities based on KPPs such as effectiveness and determine the time of execution and the type of maintenance that is most cost-efficient, without affecting and complementing the criteria for maintenance More >

  • Open Access

    ARTICLE

    STUDY ON THERMAL AND HYDRAULIC PERFORMANCE OF THE FINNED FLAT-TUBE HEAT EXCHANGER WITH SINGLE ROW AND ITS OPTIMIZATION

    Weiwei Zhang, Linghong Tang*

    Frontiers in Heat and Mass Transfer, Vol.15, pp. 1-7, 2020, DOI:10.5098/hmt.15.9

    Abstract Air-side thermal and hydraulic performance of the finned flat-tube heat exchanger with single row is experimentally investigated. The correlations of the thermal and hydraulic performance are developed based on the experimental data. The effects of various fin geometrical parameters on the thermal and hydraulic performance are investigated by a numerical method, and the influence of various parameters is analyzed in detail. Results show that heat transfer performance and pressure drop decrease with the increasing fin pitch, and heat transfer performance increases with the increase of fin length and fin height accompanying with the increase of More >

  • Open Access

    ARTICLE

    miR-122 Inhibits Hepatocarcinoma Cell Progression by Targeting LMNB2

    Xiao-Na L*i, Hong Yang, Tao Yang

    Oncology Research, Vol.28, No.1, pp. 41-49, 2020, DOI:10.3727/096504019X15615433287579

    Abstract In the present study, we investigated the role of miR-122 in hepatocarcinoma progression and explored the mechanism. In hepatocarcinoma tissues and cells, we used qRT-PCR to validate the miR-122 expression level. Next, we used colony formation by crystal violet staining assay to compare cell proliferation ability, and we used scratch test or Transwell assay to compare cell migration or invasion ability. We then conducted bioinformatics or luciferase reporter gene assay to prove the regulation effect of miR-122 on lamin B2 (LMNB2), and the biological function of LMNB2 was analyzed. We used nude mouse tumorigenicity assay… More >

  • Open Access

    ARTICLE

    RPSAP52 lncRNA Inhibits p21Waf1/CIP Expression by Interacting With the RNA Binding Protein HuR

    Daniela D’Angelo*, Claudio Arra, Alfredo Fusco*

    Oncology Research, Vol.28, No.2, pp. 191-201, 2020, DOI:10.3727/096504019X15761465603129

    Abstract Long noncoding RNAs have been recently demonstrated to have an important role in fundamental biological processes, and their deregulated expression has been found in several human neoplasias. Our group has recently reported a drastic overexpression of the long noncoding RNA (lncRNA) RPSAP52 (ribosomal protein SA pseudogene 52) in pituitary adenomas. We have shown that this lncRNA increased cell proliferation by upregulating the expression of the chromatinic proteins HMGA1 and HMGA2, functioning as a competing endogenous RNA (ceRNA) through competitively binding to microRNA-15a (miR-15a), miR-15b, and miR-16. The aim of this work was to identify further… More >

  • Open Access

    ARTICLE

    PRKAA1 Promotes Proliferation and Inhibits Apoptosis of Gastric Cancer Cells Through Activating JNK1 and Akt Pathways

    Yangmei Zhang*1, Xichang Zhou†1, Long Cheng, Xiang Wang*, Qinglin Zhang, Youwei Zhang*, Sanyuan Sun*

    Oncology Research, Vol.28, No.3, pp. 213-223, 2020, DOI:10.3727/096504019X15668125347026

    Abstract PRKAA1 (protein kinase AMP-activated catalytic subunit 1) is a catalytic subunit of AMP-activated protein kinase (AMPK), which plays a key role in regulating cellular energy metabolism through phosphorylation, and genetic variations in the PRKAA1 have been found to be associated with gastric cancer risk. However, the effect and underlying molecular mechanism of PRKAA1 on gastric cancer tumorigenesis, especially the proliferation and apoptosis, are not fully understood. Our data showed that PRKAA1 is highly expressed in BGC- 823 and MKN45 cells and is expressed low in SGC-7901 and MGC-803 cells in comparison with the other gastric… More >

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