Farouq Mohammad A. Alam¹, Sharifah Alrajhi¹, Mazen Nassar^1,2, Ahmed Z. Afify^3,*

CMC-Computers, Materials & Continua, Vol.67, No.2, pp. 2185-2202, 2021, DOI:10.32604/cmc.2021.015089

Abstract The main objective of this paper is to discuss a general family of distributions generated from the symmetrical arcsine distribution. The considered family includes various asymmetrical and symmetrical probability distributions as special cases. A particular case of a symmetrical probability distribution from this family is the Arcsine–Gaussian distribution. Key statistical properties of this distribution including quantile, mean residual life, order statistics and moments are derived. The Arcsine–Gaussian parameters are estimated using two classical estimation methods called moments and maximum likelihood methods. A simulation study which provides asymptotic distribution of all considered point estimators, 90% and 95% asymptotic confidence intervals are… More >

Prabakaran Rajamanickam¹, Shiloah Elizabeth Darmanayagam^1,*, Sunil Retmin Raj Cyril Raj²

CMC-Computers, Materials & Continua, Vol.67, No.1, pp. 709-722, 2021, DOI:10.32604/cmc.2021.014347

Abstract Liver Segmentation is one of the challenging tasks in detecting and classifying liver tumors from Computed Tomography (CT) images. The segmentation of hepatic organ is more intricate task, owing to the fact that it possesses a sizeable quantum of vascularization. This paper proposes an algorithm for automatic seed point selection using energy feature for use in level set algorithm for segmentation of liver region in CT scans. The effectiveness of the method can be determined when used in a model to classify the liver CT images as tumorous or not. This involves segmentation of the region of interest (ROI) from… More >

Sufyan Habib¹, Nawaf N. Hamadneh^2,*, S. Al wadi³, Ra’ed Masa’deh⁴

CMC-Computers, Materials & Continua, Vol.67, No.1, pp. 445-462, 2021, DOI:10.32604/cmc.2021.014047

Abstract Online Food Delivery Platforms (OFDPs) has witnessed phenomenal growth in the past few years, especially this year due to the COVID-19 pandemic. This Pandemic has forced many governments across the world to give momentum to OFD services and make their presence among the customers. The Presence of several multinational and national companies in this sector has enhanced the competition and companies are trying to adapt various marketing strategies and exploring the brand experience (BEX) dimension that helps in enhancing the brand equity (BE) of OFDPs. BEXs are critical for building brand loyalty (BL) and making companies profitable. Customers can experience… More >

Sophie Piperno-Neumann^1,*, Pascale Mariani², Vincent Servois³, Gaelle Pierron⁴, Livia LumbrosoRouic⁵, Alexandre Matet^5,6, Manuel Rodrigues¹, Nathalie Cassoux^5,6

Oncologie, Vol.22, No.4, pp. 203-212, 2020, DOI:10.32604/oncologie.2020.014102

Abstract Uveal melanoma is a rare subtype of melanoma, intrinsically different from cutaneous melanoma. Despite optimal therapeutic management allowing local control of the primary ocular tumor, 20 to 50% of patients develop metastases, mainly localized to the liver, with a poor prognosis and a 12-month median survival from the diagnosis of the metastatic disease. There is a lack of effective treatments in the metastatic setting, and dedicated strategies and trials for uveal melanoma patients are needed, based on identification of new targets and specific preclinical findings.


Résumé:
Le mélanome de l’uvée est un cancer rare, en tous points différent du mélanome… More >

Zahra Alimanesh¹, Zeynab Alimanesh¹, Fatemeh Davari², Saeedeh Shadmehri³, Mozhgan Ahmadi³, Seyed Ali Hosseini⁴, Sepideh Dolati^5,*, Alemeh Hariri Far⁶

Molecular & Cellular Biomechanics, Vol.17, No.4, pp. 155-163, 2020, DOI:10.32604/mcb.2020.011532

Abstract Diabetes mellitus (DM) disease can affect process of apoptosis by increasing oxidative stress, nevertheless exercise and crocin can improve apoptosis; therefore present study aimed to investigate the effect of continued training with crocin on apoptosis markers in liver tissue of diabetic rats. In this experimental study 32 diabetic rats based on fasting glucose divided into four groups of eight rats including: 1) sham, 2) training, 3) crocin, and 4) training with crocin also for investigate the effect of DM induction on apoptosis markers, eight healthy rats assigned in healthy control group. During eight weeks groups 2 and 4 ran 60… More >

Tingting Yang¹, Hailong Feng¹, Chengming Yang², Ge Guo³, Tieshan Li¹

Computer Systems Science and Engineering, Vol.33, No.2, pp. 157-164, 2018, DOI:10.32604/csse.2018.33.157

Abstract In this paper, the online and offline scheduling schemes towards maritime Cyber Physical Systems (CPSs), to transmit video packets generating from the interior of vessel. During the sailing from the origin port to destination port, the video packets could be delivered via the infostations shoreside. The video packets have their respective release times, deadlines, weights and processing time. The video packets only could be successfully transmitted before their deadlines. A mathematic job-machine problem is mapped. Facing distinguished challenges with unique characteristics imposed in maritime scenario, we focus on the heterogeneous networking and resource optimal scheduling technology to provide valuable insights… More >

Jose A. Silva‐Sepulveda¹, Yudy Fonseca², Irine Vodkin³, Gabrielle Vaughn¹, Robert Newbury⁴, Vera Vavinskaya⁵, Jerry Dwek⁶, James C. Perry¹, Preeti Reshamwala⁷, Cynthia Baehling⁸, James Lyon⁹, Christopher Davis¹, Jesse W. Lee¹, Hannah El‐Sabrout¹⁰, Doaa Shahbah¹¹, Laith Alshawabkeh¹², John W Moore¹, Howaida El‐Said¹

Congenital Heart Disease, Vol.14, No.4, pp. 600-608, 2019, DOI:10.1111/chd.12770

Abstract Introduction: Liver fibrosis and cirrhosis are late complications in Fontan palliation. Liver biopsy is the gold standard. The goal of this study is to correlate transjugular liver biopsy (TJLB) in the setting of Fontan palliation with noninvasive testing and hemodynamics.
Methods: Between August 2014 and July 2017, 49 Fontan patients underwent TJLB. All the patients had hemodynamic evaluation, 28 patients had MRE (magnetic reso‐ nance elastography) and 40 patients had cardiopulmonary exercise test. Histologic liver fibrosis was quantitated using traditional histologic scoring systems and a modi‐ fied Ishak congestive hepatic fibrosis score.
Results: Median age 17.8 years, median time since… More >

YONGLU WANG^1,2,*, WEI YOU¹, XUEMING LI^3,4,*

BIOCELL, Vol.44, No.2, pp. 167-174, 2020, DOI:10.32604/biocell.2020.09023

Abstract Melanoma is the deadliest type of skin cancer and which has a high ability of metastasis. Surgery is an effective method to treat I or II stage melanoma patients. However, there are few treatment options for metastatic melanoma. Gene therapy is one of the attractive options and is considered as the future direction for treating melanoma. This review mainly discusses the properties and challenges of the various gene therapies in melanoma, especially the delivery systems and gene targeting. More >

Antonio R. Mott¹, Steven R. Neish², Melissa Challman³, Timothy F. Feltes⁴

Congenital Heart Disease, Vol.12, No.3, pp. 294-300, 2017, DOI:10.1111/chd.12438

Abstract Background: The treatment of children with cardiac disease is one of the most prevalent and costly pediatric inpatient conditions. The design of inpatient medical services for children admitted to and discharged from noncritical cardiology care units, however, is undefined. North American Pediatric Cardiology Programs were surveyed to define noncritical cardiac care unit models in current practice.
Method: An online survey that explored institutional and functional domains for noncritical cardiac care unit was crafted. All questions were multi-choice with comment boxes for further explanation. The survey was distributed by email four times over a 5-month period.
Results: Most programs (n =… More >

Moira B. Hilscher¹, Jonathan N. Johnson^2,3, Frank Cetta^2,3, David J. Driscoll^2,3, John J. Poterucha¹, William Sanchez¹, Heidi M. Connolly³, Patrick S. Kamath¹

Congenital Heart Disease, Vol.12, No.2, pp. 124-132, 2017, DOI:10.1111/chd.12446

Abstract The physiological consequences of the Fontan circulation impose risk for hepatic dysfunction and may culminate in hepatic fibrosis, cirrhosis, and hepatocellular carcinoma. Consensus regarding appropriate surveillance modalities to diagnose liver disease in Fontan patients is lacking, in part due to the relative lack of strong evidence and prospective studies in this patient population. The goal of this paper is to critically review the current evidence and provide recommendations for the surveillance of hepatic complications in the post-Fontan patient population. More >