Home / Advanced Search

  • Title/Keywords

  • Author/Affliations

  • Journal

  • Article Type

  • Start Year

  • End Year

Update SearchingClear
  • Articles
  • Online
Search Results (59)
  • Open Access

    REVIEW

    Understanding cell-extracellular matrix interactions for topology-guided tissue regeneration

    AAYUSHI RANDHAWA1,2, SAYAN DEB DUTTA1, KEYA GANGULY1, TEJAL V. PATIL1,2, RACHMI LUTHFIKASARI1, KI-TAEK LIM1,2,*

    BIOCELL, Vol.47, No.4, pp. 789-808, 2023, DOI:10.32604/biocell.2023.026217

    Abstract Tissues are made up of cells and the extracellular matrix (ECM) which surrounds them. These cells and tissues are actively adaptable to enduring significant stress that occurs in daily life. This astonishing mechanical stress develops due to the interaction between the live cells and the non-living ECM. Cells in the matrix microenvironment can sense the signals and forces produced and initiate a signaling cascade that plays a crucial role in the body’s normal functioning and influences various properties of the native cells, including growth, proliferation, and differentiation. However, the matrix’s characteristic features also impact the More >

  • Open Access

    ARTICLE

    Tensile Properties and Wear Resistance of Mg Alloy Containing High Si as Implant Materials

    Mengqi Cong*, Yang Zhang, Yunlong Zhang, Xiao Liu, Yalin Lu, Xiaoping Li

    Journal of Renewable Materials, Vol.11, No.4, pp. 1977-1989, 2023, DOI:10.32604/jrm.2023.023849

    Abstract Magnesium alloy has been considered as one of the third-generation biomaterials for the regeneration and support of functional bone tissue. As a regeneration implant material with great potential applications, in-situ Mg2Si phase reinforced Mg-6Zn cast alloy was comprehensively studied and expected to possess excellent mechanical properties via the refining and modifying of Mg2Si reinforcements. The present study demonstrates that the primary and eutectic Mg2Si phase can be greatly modified by the yttrium (Y) addition. The size of the primary Mg2Si phases can be reduced to ~20 μm with an addition of 0.5 wt.% Y. This phenomenon is… More > Graphic Abstract

    Tensile Properties and Wear Resistance of Mg Alloy Containing High Si as Implant Materials

  • Open Access

    REVIEW

    Dental pulp stem cells and banking of teeth as a lifesaving therapeutic vista

    SUKUMARAN ANIL1,2,*, RAMYA RAMADOSS3, NEBU G. THOMAS4, JASMIN M. GEORGE4, VISHNUPRIYA K. SWEETY4

    BIOCELL, Vol.47, No.1, pp. 71-80, 2023, DOI:10.32604/biocell.2023.024334

    Abstract Exfoliated deciduous or an extracted healthy adult tooth can be used to harvest, process, and cryogenically preserve dental pulp stem cells. Future stem cell-based regenerative medicine methods could benefit significantly from these mesenchymal stem cells. Teeth serve as a substantial source of mesenchymal stem cells, otherwise disposed of as medical waste. Care should be taken to store this treasure trove of stem cells. Collective responsibility of patients, dentists, and physicians is necessary to ensure that this valuable resource is not wasted and that every possible dental pulp stem cell is available for use in the More >

  • Open Access

    ARTICLE

    Combination of 6-Benzylaminopurine and Thidiazuron Promotes Highly Efficient Shoot Regeneration from Cotyledonary Node of Mature Peanut (Arachis hypogaea L.) Cultivars

    Abraham Lamboro1,*, Xiao Han1, Songnan Yang1, Xueying Li1, Dan Yao2, Baixing Song1, Jun Zhang1,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.12, pp. 2619-2631, 2022, DOI:10.32604/phyton.2022.021404

    Abstract Efficient in vitro plantlet regeneration is an important step to successfully transform genes for the improvement of agronomic traits. A combination of 6-benzylaminopurine (BAP) and thidiazuron (TDZ) plant growth regulators was applied to evaluate shoot regeneration capacity whereas α-naphthalene acetic acid (NAA) combination with 6-benzylaminopurine (BAP), and 2, 4-dichlorophenoxyacetic acid (2, 4-D) with 6-benzylaminopurine were tested to optimize root induction for two peanut cultivars. The result showed combination (BAP with TDZ) was found to be effective in promoting shoot. The highest shoot regeneration frequency (93%) was obtained on a medium supplemented with 4 mg/L BAP and 0.5 mg/L… More >

  • Open Access

    ARTICLE

    Soot Distribution and Thermal Regeneration of Marine Diesel Particulate Filter

    Xiangli Wang1, Peiyong Ni2,*

    Energy Engineering, Vol.119, No.4, pp. 1697-1710, 2022, DOI:10.32604/ee.2022.021070

    Abstract Diesel particulate filter (DPF) is a leading technology reducing particle emissions from marine diesel engines. The removal or regeneration of soot in DPF is an important issue. The purpose of this study is to provide some reference strategies to design the DPF for marine diesel engines. In this paper, a mathematical model of a marine DPF was built up and the particle trap process and the regeneration dynamics were simulated. The results show that the cake soot mass concentrations from 0 to 4.2 g/L during the trap process increase linearly with the increase of the… More >

  • Open Access

    ARTICLE

    Injectable Collagen/CMC Soft Tissue Filler with Developed Flow Properties

    Reza Samanipour1, Aida Pourmostafa2, Adel Marzban2, Sara Tabatabaee3, Hasan Bahraminasab2, Amir Ali Hamidieh4, Amirhossein Tavakoli4,*

    Molecular & Cellular Biomechanics, Vol.19, No.2, pp. 97-104, 2022, DOI:10.32604/mcb.2022.019080

    Abstract Based on the remarkable demand for facial reconstitute or reshape fillers due to the dermal defects arising from specific diseases, trauma, or aging, several natural or synthetic materials have been investigated. Among the evaluated materials, decellularized dermis is one of the most biocompatible choices for the aim of skin tissue regenerative approaches. On the other hand, Carboxymethyl Cellulose (CMC), a synthetic polysaccharide, with the desirable degradability, biomechanical stability, and nontoxicity seems to be an acceptable reinforcement agent for decellularized dermis. Thus, in this research, an injectable soft tissue filler contained of human-derived decellularized collagen and More >

  • Open Access

    VIEWPOINT

    Expression analysis of OsSERK, OsLEC1 and OsWOX4 genes in rice (Oryza sativa L.) callus during somatic embryo development

    SITI NABILAH1,2; TRI HANDOYO2,3; KYUNG-MIN KIM4; MOHAMMAD UBAIDILLAH2,*

    BIOCELL, Vol.46, No.7, pp. 1633-1641, 2022, DOI:10.32604/biocell.2022.019111

    Abstract Somatic embryogenesis is an asexual reproduction process that occurs in many plant species, including rice. This process contains several totipotency markers such as Somatic Embryogenesis Receptor-like Kinase (SERK), Leafy Cotyledon1 (LEC1) and WUSCHEL-Related Homeobox4 (WOX4) and also a helpful model for embryo development and clones and transformations. Here, we report the gene expression during somatic embryo development correlates with regeneration frequency in 14 Javanica rice (pigmented and non-pigmented) using modifified N6 media supplemented with Kinetin (2.0 mg/L) and NAA (1.0 mg/L). Although there have been advances in understanding the genetic basis of somatic embryogenesis in… More >

  • Open Access

    ARTICLE

    FASTER–RCNN for Skin Burn Analysis and Tissue Regeneration

    C. Pabitha*, B. Vanathi

    Computer Systems Science and Engineering, Vol.42, No.3, pp. 949-961, 2022, DOI:10.32604/csse.2022.021086

    Abstract Skin is the largest body organ that is prone to the environment most specifically. Therefore the skin is susceptible to many damages, including burn damage. Burns can endanger life and are linked to high morbidity and mortality rates. Effective diagnosis with the help of accurate burn zone and wound depth evaluation is important for clinical efficacy. The following characteristics are associated with the skin burn wound, such as healing, infection, painand stress and keloid formation. Tissue regeneration also takes a significant amount of time for formation while considering skin healing after a burn injury. Deep… More >

  • Open Access

    VIEWPOINT

    MSCs derived extracellular vesicles as a therapeutic paragon for neurodegenerative disorders: A viewpoint

    YASHVI SHARMA1, SHARDA RAY2, SUJATA MOHANTY1,*

    BIOCELL, Vol.46, No.6, pp. 1435-1438, 2022, DOI:10.32604/biocell.2022.018612

    Abstract Neurodegenerative disorders are a vicious woe to the public health and wellness. Uncertainty in their underlying causes, lack of effective biomarkers for their early detection, existence of only supportive therapy, and their ever rising incidence creates an unmatched need for targeted therapies. Mesenchymal Stem Cells (MSCs) have found to be promising candidates for regenerative and remedial therapy in neurodegenerative disorders, however several biological risks and practical issues impede in their translational utility. Deriving from MSCs are certain Extracellular Vesicles (EVs), which aid in the paracrine action of MSCs and have lately gained the scientific interest More >

  • Open Access

    VIEWPOINT

    MSCs-exosomes in regeneration medicine: Current evidence and future perspectives

    BENSHUAI YOU1, HUI QIAN1,2,*

    BIOCELL, Vol.46, No.6, pp. 1459-1463, 2022, DOI:10.32604/biocell.2022.018378

    Abstract Exosomes, especially from mesenchymal stem cells, have attracted extensive attention in regeneration medicine. Mesenchymal stem cells derived exosomes (MSCs-exosomes) have shown anti-inflammatory, anti-oxidant, anti-apoptosis and tissue regeneration effects in a variety of tissue injury repair models. MSCs-exosomes hold many excellent properties such as low immunogenicity, biocompatibility, and targeting capability. With the in-depth study on the generation and function of exosomes, MSCs-exosomes are considered to be the bright stars in the field of regenerative medicine. However, there are still many obstacles to overcome in terms of exosomes isolation, clinical trials and safety evaluation. In this article, More >

Displaying 11-20 on page 2 of 59. Per Page