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  • Open Access

    ARTICLE

    Silica Gel from Chemical Glass Bottle Waste as Adsorbent for Methylene Blue: Optimization Using BBD

    Suprapto Suprapto, Putri Augista Nur Azizah, Yatim Lailun Ni’mah*

    Journal of Renewable Materials, Vol.11, No.12, pp. 4007-4023, 2023, DOI:10.32604/jrm.2023.031210

    Abstract This research focuses on the effective removal of methylene blue dye using silica gel synthesized from chemical glass bottle waste as an environmentally friendly and cost-effective adsorbent. The adsorption process was optimized using Box-Behnken Design (BBD) and Response Surface Methodology (RSM) to investigate the influence of pH (6; 8 and 10), contact time (15; 30 and 45 min), adsorbent mass (30; 50 and 70 mg), and initial concentration (20; 50 and 80 mg/L) of the adsorbate on the adsorption efficiency. The BBD was conducted using Google Colaboratory software, which encompassed 27 experiments with randomly assigned combinations. The silica gel synthesized… More > Graphic Abstract

    Silica Gel from Chemical Glass Bottle Waste as Adsorbent for Methylene Blue: Optimization Using BBD

  • Open Access

    REVIEW

    Exploring exosomes to provide evidence for the treatment and prediction of Alzheimer’s disease

    XIANGYU QUAN1, XUETING MA1, GUODONG LI2, XUEQI FU1, JIANGTAO LI1, LINLIN ZENG1,*

    BIOCELL, Vol.47, No.10, pp. 2163-2176, 2023, DOI:10.32604/biocell.2023.031226

    Abstract Exosomes are extracellular vesicles with a 30–150 nm diameter originating from endosomes. In recent years, scientists have regarded exosomes as an ideal small molecule carrier for the targeted treatment of Alzheimer’s disease (AD) across the blood-brain barrier due to their nanoscale size and low immunogenicity. A large amount of evidence shows that exosomes are rich in biomarkers, and it has been found that the changes in biomarker content in blood, cerebrospinal fluid, and urine are often associated with the onset of AD patients. In this paper, some recent advances in the use of exosomes in the treatment of AD are… More > Graphic Abstract

    Exploring exosomes to provide evidence for the treatment and prediction of Alzheimer’s disease

  • Open Access

    ARTICLE

    The Cotton GhWRKY91 Gene Negatively Regulates Root Elongation in Overexpressed Transgenic Arabidopsis thaliana

    Yueying Liu#, Yuqing Wang#, Lijiao Gu*

    Phyton-International Journal of Experimental Botany, Vol.92, No.11, pp. 2937-2946, 2023, DOI:10.32604/phyton.2023.043306

    Abstract WRKY transcription factors play important roles in plant growth, development, and stress responses. Our previous research has shown that the GhWRKY91 gene can delay age-, abscisic acid (ABA)-, and drought-induced leaf senescence when overexpressed in transgenic Arabidopsis plants. To explore in more depth the biological functions of the GhWRKY91 gene, we further observed the root growth of overexpressing transgenic Arabidopsis thaliana under ABA and drought treatment. In this study, we transplanted the germinated seeds of wild-type (WT) and three transgenic lines (OE-12, OE-13 and OE-20) to 1/2 MS solid medium containing ABA and different concentrations of mannitol (simulated drought treatment)… More >

  • Open Access

    ARTICLE

    Identification of lncRNAs associated with T cells as potential biomarkers and therapeutic targets in lung adenocarcinoma

    LU SUN1,2, HUAICHENG TAN1, TING YU3, RUICHAO LIANG4,*

    Oncology Research, Vol.31, No.6, pp. 967-988, 2023, DOI:10.32604/or.2023.042309

    Abstract Lung adenocarcinoma (LUAD) is the most common and deadliest subtype of lung cancer. To select more targeted and effective treatments for individuals, further advances in classifying LUAD are urgently needed. The number, type, and function of T cells in the tumor microenvironment (TME) determine the progression and treatment response of LUAD. Long noncoding RNAs (lncRNAs), may regulate T cell differentiation, development, and activation. Thus, our aim was to identify T cell-related lncRNAs (T cell-Lncs) in LUAD and to investigate whether T cell-Lncs could serve as potential stratifiers and therapeutic targets. Seven T cell-Lncs were identified to further establish the T… More >

  • Open Access

    ARTICLE

    Growth and Transcriptomics Analysis of Michelia macclurei Dandy Plantlets with Different LED Quality Treatments

    Zhaoli Chen, Ying Liu*, Bingshan Zeng, Qingbin Jiang, Shengkun Wang, Xiangyang Li

    Phyton-International Journal of Experimental Botany, Vol.92, No.10, pp. 2891-2906, 2023, DOI:10.32604/phyton.2023.030664

    Abstract Michelia macclurei Dandy is a significant tree species that has extensive cultivation for forestry and horticulture purposes in southern China, owing to its economic and practical importance. Light quality influences plantlet growth and development during tissue culture. However, the growth characteristic and molecular regulation of M. macclurei under different light quality conditions are not well understood yet. In this study, we investigated the morphological, chlorophyll content, and transcriptomic responses of M. macclurei plantlets under different light-emitting diode (LED) qualities, including white, blue, and red light. The results showed that blue light significantly increased plant height (21.29%) and leaf number (18.65%),… More >

  • Open Access

    PROCEEDINGS

    Numerical Simulation of Multiphase Flow in Subsurface Reservoirs: Existing Challenges and New Treatments

    Shuyu Sun1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.27, No.2, pp. 1-2, 2023, DOI:10.32604/icces.2023.09671

    Abstract Two or multiple phases commonly occur as fluid mixture in petroleum industry, where oil, gas and water are often produced and transported together. As a result, petroleum reservoir engineers spent great efforts in the development and production of oil and gas reservoirs by conducting and interpolating the simulation of multiphase flows in porous geological formation. Meanwhile, environmental scientists use subsurface flow and transport models to investigate and compare for example various schemes to inject and store CO2 in subsurface geological formations, such as depleted reservoirs and deep saline aquifers. In this work, we first present an introduction of numerical simulation… More >

  • Open Access

    PROCEEDINGS

    Multi-physics Simulation of Tar-Rich Coal in-situ Pyrolysis in the Fractured Porous Zone with Multi-Region Homogenization Treatment

    Qianhao Ye1, Mingjie Li1, Jingyuan Hao1, Zibo Huang1, Jinjia Wei1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.25, No.4, pp. 1-1, 2023, DOI:10.32604/icces.2023.08826

    Abstract The macroscopic tar-rich coal in-situ pyrolysis (TCISP) multi-physics simulation is conducted, in the fractured porous zone, by coupling heat transfer, fluid flow, and chemical reaction. A novel TCISP pattern of gas injection between fractured zones is proposed, by treating the fractured porous zone as a homogeneous porosity gradient descending region. In this case, nearly 11500 kg of oil can be produced within 6 months from a 10*10*1 m3 area. The influence of the fractured zone and porosity are investigated. Results indicated that gas injection between fractured zones is more conducive to rapid production, compared with the traditional case that gas… More >

  • Open Access

    PROCEEDINGS

    High-temperature Fatigue Performance of Laser Directed Energy Deposited Ni-Based Superalloy Under Different Heat Treatment

    Zhenan Zhao1,*, Weizhu Yang2,3, Lei Li2, Shouyi Sun2, Yan Zeng2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.25, No.3, pp. 1-2, 2023, DOI:10.32604/icces.2023.010342

    Abstract The hot section components are usually in service under cyclic loading in an extreme working environment with high rotational speed at high temperatures, which is prone to fatigue failure. It is reported that fatigue related failures have accounted for over 50% of all failures of hot section components. Consequently, fatigue related failure at high temperature is one of the most important factors that shortens the service life of hot section components. Ni-based superalloy GH4169, similar as Inconel 718 (IN718), is a γ′′ and γ′ precipitation strengthened alloy. For decades, GH4169 superalloy keeps being an important material in hot section components… More >

  • Open Access

    REVIEW

    Microglial TRPV1 in epilepsy: Is it druggable for new antiepileptic treatment?

    JIAO HU, JIALU MO, XIANGLIN CHENG*

    BIOCELL, Vol.47, No.8, pp. 1689-1701, 2023, DOI:10.32604/biocell.2023.029409

    Abstract Epilepsy is one of the most common neurological diseases worldwide with a high prevalence and unknown pathogenesis. Further, its control is challenging. It is generally accepted that an imbalance between the excitatory and inhibitory properties of the central nervous system (CNS) leads to a large number of abnormally synchronized neuronal discharges in the brain. Transient receptor potential vanilloid protein type 1 (TRPV1) is a non-selective cation channel that contributes to the regulation of the nervous system and influences the excitability of the nervous system. This includes the release of neurotransmitters, action potential generation due to alterations in ion channels, synaptic… More >

  • Open Access

    ARTICLE

    Enhancing Hydrocarbon-Rich Bio-Oil Production via Catalytic Pyrolysis Fortified with Microorganism Pretreatment

    Jiapeng Wang1, Bo Zhang1,*, Haoqiang Cheng1, Zhixiang Xu2

    Journal of Renewable Materials, Vol.11, No.10, pp. 3595-3612, 2023, DOI:10.32604/jrm.2023.030005

    Abstract A new method of pretreatment of corn straw with Phanerochaete chrysosporium combined with pyrolysis was proposed to improve the quality of bio-oil. The characterization results demonstrated that microbial pretreatment was an effective method to decrease the lignin, which can achieve a maximum removal rate of 44.19%. Due to the destruction of biomass structure, the content of alkali metal and alkaline earth metal is reduced. Meanwhile, the depolymerized biomass structure created better pyrolysis conditions to promote the pyrolysis efficiency, increase the average decomposition rate of pyrolysis and reduce the residue. In fast pyrolysis, because of the enrichment of cellulose and the… More > Graphic Abstract

    Enhancing Hydrocarbon-Rich Bio-Oil Production via Catalytic Pyrolysis Fortified with Microorganism Pretreatment

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