Le Anh Duc^a , Nguyen Hay^a, Pham Van Kien^b,*

Frontiers in Heat and Mass Transfer, Vol.18, pp. 1-7, 2022, DOI:10.5098/hmt.18.44

Abstract This study determined the most appropriate thin layer drying model, the effective moisture diffusivity and the activation energy of moisture within Ganoderma lucidum in radio frequency (RF) assisted heat pump drying method. The thin layer drying experiments were conducted with input drying parameters such as: drying temperature of 40, 45 and 50°C and RF power of 0.65, 1.3 and 1.95 kW. In order to select a suitable form of drying curve, seven different thin layer drying models (Lewis, Page, Modified Page, Henderson and Pabis, Verma, Midilli, and Wang and Singh) were fitted to the experimental data. The Verma model was… More >

P. Madhu Sravanthi^a,b, M. Radha Madhavi^a,*

Frontiers in Heat and Mass Transfer, Vol.19, pp. 1-9, 2022, DOI:10.5098/hmt.19.40

Abstract In this paper, reaction of magnetic field and activation energy is applied on nanoparticles and swimming gyrotactic microorganisms under the viscous dissipation is inspecting. The effect of thermophoresis and Brownian motion is also considered. The PDEs are naturalized into ODEs by using similarity transformations. To solving the PDEs by using RK-Fehlberg with shooting approach by MATLAB software. The effect of magnetic parameter, Schmidt number, Prandtl number, Brownian motion, thermophoresis, Peclet number, porosity parameter, on velocity, temperature, concentration, motile microorganism density portrait is in detailed it is discussed and the eventualities are demonstrated in graphs. The effects of these factors on… More >

P.S.S. Nagalakshmi, N. Vijaya^*

Frontiers in Heat and Mass Transfer, Vol.19, pp. 1-18, 2022, DOI:10.5098/hmt.19.17

Abstract The main emphasis of this study is to examine the entropy generation of the spatial-temporal state of Bingham visco-plastic nanofluid flow between parallel plates are solved numerically using adequate similarity solutions. Python with BVP solver is used to interpret the results of the adopted model. Heat and mass transfer rate with respect to yield stress was investigated. The results report that the entopy generation of nanofluids exploring single and multiwalled carbon nanotubes dims with the increasing local thermal Peclet number nearer the lower and upper plates. Researchers have established that entropy generation can be reduced by increasing Fourier’s number (Fe)… More >

Jianping Deng¹, Qianqian Zhang¹, Yuling Lan¹, Lingcong Luo¹, Zimin Dai¹, Zhonghang Lin¹, Zhixin Lu¹, Jiancheng Yuan¹, Yiqi Fu¹, Lu Luo^2,*, Weigang Zhao^1,*

Journal of Renewable Materials, Vol.11, No.6, pp. 2631-2646, 2023, DOI:10.32604/jrm.2023.027163

Abstract The development and utilization of biomass and agroforestry processing byproducts for high-value applications have been an important topic in the field of renewable materials research. Based on this, a two-step microwave hydrothermal pre-carbonization and KOH activation method was proposed to synthesize tannin-based activated carbons with a high specific surface area, hierarchical pore structure, and good electrochemical performance. The microstructure, texture properties, and physicochemical characteristics were investigated. The results show that the prepared tannin-based activated carbons presented a hierarchical pore structure (micro- and mesopores) with a specific surface area as high as 997.46 m³ g⁻¹ . The electrochemical analysis shows that… More > Graphic Abstract

Seung-Yeon Hwang¹, Jeong-Joon Kim^2,*

CMC-Computers, Materials & Continua, Vol.75, No.2, pp. 3553-3569, 2023, DOI:10.32604/cmc.2023.037028

Abstract Recently, deep learning has achieved remarkable results in fields that require human cognitive ability, learning ability, and reasoning ability. Activation functions are very important because they provide the ability of artificial neural networks to learn complex patterns through nonlinearity. Various activation functions are being studied to solve problems such as vanishing gradients and dying nodes that may occur in the deep learning process. However, it takes a lot of time and effort for researchers to use the existing activation function in their research. Therefore, in this paper, we propose a universal activation function (UA) so that researchers can easily create… More >

ZHIXUN XIAO¹, QIUYUN XU¹, HAIQING WANG¹, XIAOTONG ZHOU², YANTING ZHU¹, CHENGBEI BAO¹, LIHONG CHEN¹, PENG ZHANG¹, MIN LIN¹, CHAO JI^1,*, TING GONG^3,*

Oncology Research, Vol.31, No.1, pp. 71-82, 2023, DOI:10.32604/or.2022.028075

Abstract Cutaneous squamous cell carcinoma (cSCC), a type of non-melanoma skin cancer (NMSC), is the most common malignancy worldwide. Thioredoxin (TXN) domain-containing protein 9 (TXNDC9) is a member of the TXN family that is important in cell differentiation. However, the biological function of this protein in cancer, particularly cSCC, is still unknown. In the present study, our experiments revealed the protective effects of TXNDC9 on UV-B-irritated cSCC cells. The initial findings showed that TXNDC9 is significantly upregulated in cSCC tissue and cells compared to normal skin tissue and keratinocytes. UV-B radiation robustly induces the expression of TXNDC9, and UV-B-induced cSCC cell… More >

XIAOYIN LI^1,#, QIAN WANG^2,#, HONGFENG LIANG^3,#, SHISHENG CHEN^4,#, HAIWEN CHEN^1,#, YAOYONG LU^1,*, CHANGFU YANG^1,*

Oncology Research, Vol.30, No.2, pp. 77-87, 2022, DOI:10.32604/or.2022.026511

Abstract In this study, we investigated the functional role of eukaryotic initiation factor 5B (EIF5B) in hepatocellular carcinoma (HCC) and the underlying mechanisms. Bioinformatics analysis demonstrated that the EIF5B transcript and protein levels as well as the EIF5Bcopy number were significantly higher in the HCC tissues compared with the non-cancerous liver tissues. Down-regulation of EIF5B significantly decreased proliferation and invasiveness of the HCC cells. Furthermore, EIF5B knockdown suppressed epithelial-mesenchymal transition (EMT) and the cancer stem cell (CSC) phenotype. Down-regulation of EIF5B also increased the sensitivity of HCC cells to 5-fluorouracil (5-FU). In the HCC cells, activation of the NF-kappa B signaling… More >

QIAOJIN JIA^1,2, YUEJUN FU^1,*

BIOCELL, Vol.47, No.3, pp. 627-645, 2023, DOI:10.32604/biocell.2023.026182

Abstract Background: The immune system of insects exerts fundamentally different antiviral mechanisms than mammals. MicroRNAs (miRNAs) play vital roles in developing insect antiviral immunity. MiRNAs expression profiles of insects changed significantly during baculovirus infection. Methods: Differential expression profiles of miRNAs in Spodoptera frugiperda were monitored by next-generation sequencing (NGS) and RT-qPCR during Autographa californica multiple nucleopolyhedrovirus (AcMNPV) infection. The transcription levels of genes were detected by RT-qPCR. The 50% tissue culture infective dose (TCID50) endpoint dilution assay was used to determine the proliferation of progeny virus. Results: NGS revealed that 49 miRNAs were differentially expressed in Sf9 cells, and 10 of… More >

YONGDAE YOON^1,#, SOONJAE HWANG^1,2,#, FATEMA TUJ SAIMA^3,#, MOON YOUNG KIM^1,3,4, SOON KOO BAIK^1,3,4,*, YOUNG WOO EOM^1,3,*

BIOCELL, Vol.47, No.3, pp. 669-676, 2023, DOI:10.32604/biocell.2023.025365

Abstract Background: Activated hepatic stellate cells (HSCs) are closely involved in the initiation, perpetuation, and resolution of liver fibrosis. Pro-inflammatory cytokine levels are positively correlated with the transition from liver injury to fibrogenesis and contribute to HSC pathophysiology in liver fibrosis. Methods: In this study, we investigated the effect of the pro-inflammatory cytokine interleukin (IL)-1β on the proliferation and signaling pathways involved in fibrogenesis in LX-2 cells, an HSC cell line, using western blotting and cell proliferation assays. Results: IL-1β increased the proliferation rate and α-smooth muscle actin (SMA) expression of LX-2 cells in a dose-dependent manner. Within 1 h after… More >

Xue Cui^1,2, Min Peng², Honglei Chen^1,*

Oncologie, Vol.24, No.4, pp. 665-678, 2022, DOI:10.32604/oncologie.2022.023641

Abstract The emergence of tumor immunotherapy, especially immune checkpoint inhibitors (ICIs), has brought new life to cancer treatment, and ICIs can effectively treat various tumors. Among the immune anti-cancer therapies, PD-1 is undoubtedly the hot target after CTLA-4, but due to the ineffectiveness of PD-1 in treating certain tumors, researchers have shifted their focus to other combination targets, such as LAG-3, TIM3, IDO-1, etc. One of these promising targets is LAG-3, a target with multiple clinical trials, which has increasingly shown to be an inhibitory co-receptor that plays a vital role in autoimmunity, cancer immunity, and anti-infection immunity. Immune combination therapy… More >