Huan Zhou^1,#, Jin Kang^2,#, Jun Gao^2,*, Xiaoyuan Feng¹, Li Zhou², Xia Xiao², Zhengliang Meng², Chengwen Guo²

Congenital Heart Disease, Vol.17, No.6, pp. 697-707, 2022, DOI:10.32604/chd.2022.022648

Abstract Background: Real-time three-dimensional echocardiography (RT-3DE) could obtain ventricular volume and ejection fraction rapidly and non-invasively without relying on ventricular morphology. This study aims to use RT-3DE to evaluate the changes in biventricular volume and systolic function in children with ventricular septal defect (VSD) and moderate to severe pulmonary hypertension (PH) before surgery. Methods: In this study 18 children with VSD and moderate to severe PH (VSD + PH Group) and 18 healthy children of the same age (Control Group) were recruited. Biventricular volume and systolic function were evaluated by RT-3DE. The measurements included: left and right ventricular volume indexed to… More > Graphic Abstract

Taher M. Ghazal^1,2, Sundus Munir^3,4, Sagheer Abbas³, Atifa Athar⁵, Hamza Alrababah¹, Muhammad Adnan Khan^6,*

Intelligent Automation & Soft Computing, Vol.36, No.1, pp. 11-22, 2023, DOI:10.32604/iasc.2023.030125

Abstract Autism spectrum disorder (ASD) is a challenging and complex neuro-development syndrome that affects the child’s language, speech, social skills, communication skills, and logical thinking ability. The early detection of ASD is essential for delivering effective, timely interventions. Various facial features such as a lack of eye contact, showing uncommon hand or body movements, babbling or talking in an unusual tone, and not using common gestures could be used to detect and classify ASD at an early stage. Our study aimed to develop a deep transfer learning model to facilitate the early detection of ASD based on facial features. A dataset… More >

Pornrawee Plearntummakun¹, Chodchanok Vijarnsorn^1,*, Kritvikrom Durongpisitkul¹, Prakul Chanthong¹, Paweena Chungsomprasong¹, Supaluck Kanjanauthai¹, Thita Pacharapakornpong¹, Jarupim Soongswang¹, Thaworn Subtaweesin²

Congenital Heart Disease, Vol.17, No.4, pp. 463-478, 2022, DOI:10.32604/chd.2022.021545

Abstract Background: Congenital coronary artery fistula (CCAF) is a rare anomaly. Treatment strategies tend to close the defect with a symptomatic and significant shunt, primarily based on expert consensus and case series. Results for long-term follow-up in children are limited Methods: We conducted a retrospective study to assess clinical and imaging outcomes of children with CCAF at Siriraj Hospital, Thailand during 2000–2020. Patients with single ventricle were excluded. Treatment strategies [surgical closure (SC), and percutaneous closure (PC)] were classified and the clinical outcomes at the follow-up in 2021, including coronary thrombosis, myocardial ischemia, and the results of cardiovascular imaging were reviewed.… More > Graphic Abstract

Hugues Lucron^1,*, Alban-Elouen Baruteau^2,3, Caroline Ovaert⁴, Ali Houeijeh⁵, Mélanie Brard¹, Patrice Guerin², François Bourlon⁶, Claire Dauphin⁷, Saskia Tuttle¹, Maha Tagorti³, Rishika Banydeen⁸, François Godart⁵

Congenital Heart Disease, Vol.17, No.4, pp. 421-436, 2022, DOI:10.32604/chd.2022.020835

Abstract Objectives: We aim to describe the efficacy, safety, and characteristics of the Amplatzer Vascular Plug (AVP) II and IV “off-label” use for multiple cardiovascular occlusions in children under 10 years. Methods: Observational retrospective multicenter (2007–2020, 6 centers) review of paediatric procedures using AVP II or IV. Results: A total of 125 children (49.6% aged ≤ 1 year, 147 lesions) underwent 136 successive procedures (success rate: 98.5%) using 169 devices (109 AVP IV, 60 AVP II). The mean device diameter was 7.7 ± 3.2 mm (4–20 mm). The median AVP size to vessel diameter ratio was 1.3 (0–2). The median age and weight… More > Graphic Abstract

Chunmou Li^*1, Xiaomin Peng^*1, Chuchu Feng^*1, Xilin Xiong^*, Jianxin Li^†, Ning Liao^‡, Zhen Yang^§, Aiguo Liu^¶, Pingping Wu^*, Xuehong Liang^†, Yunyan He^‡, Xin Tian^§, Yunbi Lin^§, Songmi Wang^¶, Yang Li^*

Oncology Research, Vol.28, No.7-8, pp. 791-800, 2020, DOI:10.3727/096504021X16184815905096

Abstract This nonrandomized, multicenter cohort, open-label clinical trial evaluated the efficacy and safety of combined chemotherapy with arsenic trioxide (ATO) in children with stage 4/M neuroblastoma (NB). We enrolled patients who were newly diagnosed with NB and assessed as stage 4/M and received either traditional chemotherapy or ATO combined with chemotherapy according to their own wishes. Twenty-two patients were enrolled in the trial group (ATO combined with chemotherapy), and 13 patients were enrolled in the control group (traditional chemotherapy). Objective response rate (ORR) at 4 weeks after completing induction chemotherapy was defined as the main outcome, and adverse events were monitored… More >

S. P. Abirami^1,*, G. Kousalya¹, R. Karthick²

Intelligent Automation & Soft Computing, Vol.35, No.1, pp. 595-607, 2023, DOI:10.32604/iasc.2023.027562

Abstract Autism Spectrum Disorder (ASD) is found to be a major concern among various occupational therapists. The foremost challenge of this neurodevelopmental disorder lies in the fact of analyzing and exploring various symptoms of the children at their early stage of development. Such early identification could prop up the therapists and clinicians to provide proper assistive support to make the children lead an independent life. Facial expressions and emotions perceived by the children could contribute to such early intervention of autism. In this regard, the paper implements in identifying basic facial expression and exploring their emotions upon a time-variant factor. The… More >

Hisham A. Ramy, Soheir H. Elghonemy, Nesreen M. Mohsen, Safi M. Nagib^*, Mohamed Y. Mohamed

International Journal of Mental Health Promotion, Vol.24, No.4, pp. 539-550, 2022, DOI:10.32604/ijmhp.2022.020108

Abstract Many children with mental health problems in Egypt, as in many other countries, do not receive the help they need. Investigating the pathways of care is crucial for the early detection and treatment of these children. This study examined referral patterns and the duration of untreated psychiatric illness of 350 children attending two urban clinical settings in Egypt. Diagnoses were made using the Kiddie Schedule for Affective Disorder and Schizophrenia for School-aged children present and lifetime (K-SADS-PL), Child behavior checklist (CBCL,) and the Stanford-Binet Intelligence Scale. For 46.3%, the most distressing symptom was behavioral problems. A delay in seeking psychiatric… More >

Mengxian Zhao¹, Yonghao You², Jinming Li³, Sean Healy⁴, Alyx Taylor⁵, Zhihao Zhang³, Linlin Li⁶, Liye Zou^7,*

International Journal of Mental Health Promotion, Vol.24, No.4, pp. 475-489, 2022, DOI:10.32604/ijmhp.2022.021361

Abstract Therapeutic horseback riding (THR) as an animal-assisted intervention is one of the innovative approaches emerging in the treatment for children with autism spectrum disorder (ASD). The current study was designed to investigate the effects of a 12-week, twice a week THR program on motor skills in sixty-eight children with ASD aged 5–10 years old. All participants selected met the DSM-V criteria for ASD, and a total of fifty-three participants completed the study. A randomized controlled trial design was utilized for the study. Data was collected via a pre-THR test, interim-THR test, and post-THR test to investigate the possible changes in… More >

Jutarat Tanasansuttiporn¹, Maliwan Oofuvong^1,*, Wirat Wasinwong¹, Voravit Chittithavorn², Pongsanae Duangpakdee², Jirayut Jarutach³, Qistina Yunuswangsa¹

Congenital Heart Disease, Vol.17, No.3, pp. 245-267, 2022, DOI:10.32604/chd.2022.021778

Abstract Background: Studies on predictors of health-related quality of life (HRQOL) in pediatric patients with cyanotic heart disease who are waiting for the next stage and those who have undergone total repair are scarce. Therefore, we aimed to identify such predictors in children who received the modified Blalock–Taussig shunt (MBTS) and those who underwent total repair. Methods: In this historical cohort and concurrent follow-up study, data of children who underwent MBTS at the age of 0–3 years between January 2005 and December 2016 at a super-tertiary care hospital in Southern Thailand were obtained. Children who were alive in December 2017 were… More > Graphic Abstract

Muzi Li^1,4, Hong Meng^1,4,*, Liang Zhang², Yuzi Zhou³, Chao Liang⁴, Zhiling Luo⁴, Hao Wang^1,*

Congenital Heart Disease, Vol.17, No.3, pp. 231-244, 2022, DOI:10.32604/chd.2022.019480

Abstract Background: Children are at risk of extubation failure after congenital heart disease surgery. Such cases should be identified to avoid possible adverse consequences of failed extubation. This study aimed to identify ultrasound predictors of successful extubation in children who underwent cardiac surgery. Methods: Children aged 3 months to 6 years who underwent cardiac surgery (if they were intubated for >6 h and underwent a spontaneous breathing trial) were included in this study. Results: We included 83 children who underwent surgery for congenital heart disease. Transthoracic echocardiography and lung ultrasound were performed immediately before spontaneous breathing trials. Upon spontaneous breathing trial… More >