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  • Open Access

    ARTICLE

    ELM-APDPs: An Explainable Ensemble Learning Method for Accurate Prediction of Druggable Proteins

    Mujeebu Rehman1, Qinghua Liu1, Ali Ghulam2, Tariq Ahmad3, Jawad Khan4,*, Dildar Hussain5,*, Yeong Hyeon Gu5

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.1, pp. 779-805, 2025, DOI:10.32604/cmes.2025.067412 - 30 October 2025

    Abstract Identifying druggable proteins, which are capable of binding therapeutic compounds, remains a critical and resource-intensive challenge in drug discovery. To address this, we propose CEL-IDP (Comparison of Ensemble Learning Methods for Identification of Druggable Proteins), a computational framework combining three feature extraction methods Dipeptide Deviation from Expected Mean (DDE), Enhanced Amino Acid Composition (EAAC), and Enhanced Grouped Amino Acid Composition (EGAAC) with ensemble learning strategies (Bagging, Boosting, Stacking) to classify druggable proteins from sequence data. DDE captures dipeptide frequency deviations, EAAC encodes positional amino acid information, and EGAAC groups residues by physicochemical properties to generate… More >

  • Open Access

    ARTICLE

    Phytochemicals, Antioxidation, and Heat Stability of Aqueous Extracts from Cherry (Prunus serrulata) Petals

    Sy-Yu Shiau*, Shuting Ni, Yanli Yu, Songling Cai, Wenbo Huang

    Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 3047-3060, 2025, DOI:10.32604/phyton.2025.070289 - 29 October 2025

    Abstract Consumers are increasingly demanding natural colorants that are safe and offer health benefits. In addition to their ornamental characteristics, Kanzan cherry (KC) blossoms present a promising source of red-hued natural colorants and functional bioactive substances. This research utilized distilled water to extract KC petals (KCP) and their ground powders (KCPP) under varying temperatures (30°C–90°C) and times (30–180 min). The total monomeric anthocyanins (TMAC) and total phenolics (TPC) in the extracts were evaluated via the pH differential and Folin–Ciocalteu methods. Antioxidant capacities were assessed by DPPH free radical scavenging ability and reducing power. Results indicated that… More >

  • Open Access

    ARTICLE

    A Lightweight Multimodal Deep Fusion Network for Face Antis Poofing with Cross-Axial Attention and Deep Reinforcement Learning Technique

    Diyar Wirya Omar Ameenulhakeem*, Osman Nuri Uçan

    CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 5671-5702, 2025, DOI:10.32604/cmc.2025.070422 - 23 October 2025

    Abstract Face antispoofing has received a lot of attention because it plays a role in strengthening the security of face recognition systems. Face recognition is commonly used for authentication in surveillance applications. However, attackers try to compromise these systems by using spoofing techniques such as using photos or videos of users to gain access to services or information. Many existing methods for face spoofing face difficulties when dealing with new scenarios, especially when there are variations in background, lighting, and other environmental factors. Recent advancements in deep learning with multi-modality methods have shown their effectiveness in… More >

  • Open Access

    ARTICLE

    RPMS-DSAUnet: A Segmentation Model for the Pancreas in Abdominal CT Images

    Tiren Huang, Chong Luo, Xu Li*

    CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 5847-5865, 2025, DOI:10.32604/cmc.2025.067986 - 23 October 2025

    Abstract Automatic pancreas segmentation in CT scans is crucial for various medical applications including early disease detection, treatment planning and therapeutic evaluation. However, the pancreas’s small size, irregular morphology, and low contrast with surrounding tissues make accurate pancreas segmentation still a challenging task. To address these challenges, we propose a novel RPMS-DSAUnet for accurate automatic pancreas segmentation in abdominal CT images. First, a Residual Pyramid Squeeze Attention module enabling hierarchical multi-resolution feature extraction with dynamic feature weighting and selective feature reinforcement capabilities is integrated into the backbone network, enhancing pancreatic feature extraction and improving localization accuracy.… More >

  • Open Access

    ARTICLE

    Citric Acid Optimizes Lead (Pb) Phytoextraction in Mung Bean (Vigna radiata (L.) Wilczek) by Regulating Nutrient Uptake and Photosynthesis

    Hafiza Saima Gul1,2,*, Mumtaz Hussain1, Tayyaba Sanaullah3, Habib-ur-Rehman Athar2, Ibrahim Al-Ashkar4, Muhammad Kamran5, Mohammed Antar6, Ayman El Sabagh7,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.9, pp. 2893-2909, 2025, DOI:10.32604/phyton.2025.058816 - 30 September 2025

    Abstract The low efficiency of phytoextraction of lead (Pb) from agricultural fields poses a significant agricultural challenge. Organic chelating agents can influence Pb bioavailability in soil, affecting its uptake, transport, and toxicity in plants. This study aimed to assess the impact of citric acid (CA) and diethylenetriaminepentaacetic acid (DTPA) on chelate-assisted phytoextraction of Pb and its effect on growth and physiology of two cultivars (07001; 07002) of mung bean (Vigna radiata). The cultivars of mung bean were exposed to 60 mg·L−1 lead chloride (PbCl2) solution, with or without the addition of 300 mg·L−1 CA or 500 mg·L−1 DTPA, until… More >

  • Open Access

    ARTICLE

    3D Enhanced Residual CNN for Video Super-Resolution Network

    Weiqiang Xin1,2,3,#, Zheng Wang4,#, Xi Chen1,5, Yufeng Tang1, Bing Li1, Chunwei Tian2,5,*

    CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 2837-2849, 2025, DOI:10.32604/cmc.2025.069784 - 23 September 2025

    Abstract Deep convolutional neural networks (CNNs) have demonstrated remarkable performance in video super-resolution (VSR). However, the ability of most existing methods to recover fine details in complex scenes is often hindered by the loss of shallow texture information during feature extraction. To address this limitation, we propose a 3D Convolutional Enhanced Residual Video Super-Resolution Network (3D-ERVSNet). This network employs a forward and backward bidirectional propagation module (FBBPM) that aligns features across frames using explicit optical flow through lightweight SPyNet. By incorporating an enhanced residual structure (ERS) with skip connections, shallow and deep features are effectively integrated,… More >

  • Open Access

    ARTICLE

    Attention U-Net for Precision Skeletal Segmentation in Chest X-Ray Imaging: Advancing Person Identification Techniques in Forensic Science

    Hazem Farah1, Akram Bennour1,*, Hama Soltani1, Mouaaz Nahas2, Rashiq Rafiq Marie3, Mohammed Al-Sarem3,4,*

    CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 3335-3348, 2025, DOI:10.32604/cmc.2025.067226 - 23 September 2025

    Abstract This study presents an advanced method for post-mortem person identification using the segmentation of skeletal structures from chest X-ray images. The proposed approach employs the Attention U-Net architecture, enhanced with gated attention mechanisms, to refine segmentation by emphasizing spatially relevant anatomical features while suppressing irrelevant details. By isolating skeletal structures which remain stable over time compared to soft tissues, this method leverages bones as reliable biometric markers for identity verification. The model integrates custom-designed encoder and decoder blocks with attention gates, achieving high segmentation precision. To evaluate the impact of architectural choices, we conducted an… More >

  • Open Access

    ARTICLE

    Identification of Visibility Level for Enhanced Road Safety under Different Visibility Conditions: A Hierarchical Clustering-Based Learning Model

    Asmat Ullah1, Yar Muhammad1,*, Bakht Zada1, Korhan Cengiz2, Nikola Ivković3,*, Mario Konecki3, Abid Yahya4

    CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 3767-3786, 2025, DOI:10.32604/cmc.2025.067145 - 23 September 2025

    Abstract Low visibility conditions, particularly those caused by fog, significantly affect road safety and reduce drivers’ ability to see ahead clearly. The conventional approaches used to address this problem primarily rely on instrument-based and fixed-threshold-based theoretical frameworks, which face challenges in adaptability and demonstrate lower performance under varying environmental conditions. To overcome these challenges, we propose a real-time visibility estimation model that leverages roadside CCTV cameras to monitor and identify visibility levels under different weather conditions. The proposed method begins by identifying specific regions of interest (ROI) in the CCTV images and focuses on extracting specific… More >

  • Open Access

    ARTICLE

    BSDNet: Semantic Information Distillation-Based for Bilateral-Branch Real-Time Semantic Segmentation on Street Scene Image

    Huan Zeng, Jianxun Zhang*, Hongji Chen, Xinwei Zhu

    CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 3879-3896, 2025, DOI:10.32604/cmc.2025.066803 - 23 September 2025

    Abstract Semantic segmentation in street scenes is a crucial technology for autonomous driving to analyze the surrounding environment. In street scenes, issues such as high image resolution caused by a large viewpoints and differences in object scales lead to a decline in real-time performance and difficulties in multi-scale feature extraction. To address this, we propose a bilateral-branch real-time semantic segmentation method based on semantic information distillation (BSDNet) for street scene images. The BSDNet consists of a Feature Conversion Convolutional Block (FCB), a Semantic Information Distillation Module (SIDM), and a Deep Aggregation Atrous Convolution Pyramid Pooling (DASP). More >

  • Open Access

    REVIEW

    Extraction, Utilization, Functional Modification, and Application of Cellulose and Its Derivatives

    Wohua He, Fangji Wu, Haoqun Hong*

    Journal of Renewable Materials, Vol.13, No.9, pp. 1707-1763, 2025, DOI:10.32604/jrm.2025.02025-0005 - 22 September 2025

    Abstract Under the background of the current energy crisis and environmental pollution, the development of green and sustainable materials has become particularly urgent. As one of the most abundant natural polymers on earth, cellulose has attracted wide attention due to its green recycling, sustainable development, degradability, and low cost. Therefore, cellulose and its derivatives were used as the starting point for comprehensive analysis. First, the basic structural properties of cellulose were discussed, and then the extraction and utilization methods of cellulose were reviewed, including Sodium Hydroxide based solvent system, N, N-Dimethylacetamide/Lithium Chloride System, N-Methylmorpholine-N-Oxide (NMMO) system, More > Graphic Abstract

    Extraction, Utilization, Functional Modification, and Application of Cellulose and Its Derivatives

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