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  • Open Access

    ARTICLE

    Anemarsaponin B mitigates acute pancreatitis damage in mice through apoptosis reduction and MAPK pathway modulation

    YI HU1,#, ZHONGYANG REN2,#, ZHENGZHONG ZHAO1, YONGJIA HUANG3, WANTING HUANG3, JIE LIU3,*, LING DING3,*

    BIOCELL, Vol.48, No.5, pp. 745-758, 2024, DOI:10.32604/biocell.2024.049140 - 06 May 2024

    Abstract Background: Acute pancreatitis (AP), known for its rapid onset and significant incidence and mortality rates, presents a clinical challenge due to the limited availability of effective treatments and preventive measures. Anemarsaponin B (ASB) has emerged as a potential therapeutic agent, demonstrating capabilities in reducing immune inflammation, positioning it as a promising candidate for AP treatment. Methods: We investigated the effects of ASB on AP in mice, induced by caerulein and lipopolysaccharide (LPS). Peripheral blood samples were collected 24 h post-induction with caerulein to assess of key biomarkers including lipase, amylase, TNF-α, IL-1β, IL-6, SOD, and… More >

  • Open Access

    ARTICLE

    Automated Algorithms for Detecting and Classifying X-Ray Images of Spine Fractures

    Fayez Alfayez*

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1539-1560, 2024, DOI:10.32604/cmc.2024.046443 - 25 April 2024

    Abstract This paper emphasizes a faster digital processing time while presenting an accurate method for identifying spine fractures in X-ray pictures. The study focuses on efficiency by utilizing many methods that include picture segmentation, feature reduction, and image classification. Two important elements are investigated to reduce the classification time: Using feature reduction software and leveraging the capabilities of sophisticated digital processing hardware. The researchers use different algorithms for picture enhancement, including the Wiener and Kalman filters, and they look into two background correction techniques. The article presents a technique for extracting textural features and evaluates three… More >

  • Open Access

    ARTICLE

    Improving Thyroid Disorder Diagnosis via Ensemble Stacking and Bidirectional Feature Selection

    Muhammad Armghan Latif1, Zohaib Mushtaq2, Saad Arif3, Sara Rehman4, Muhammad Farrukh Qureshi5, Nagwan Abdel Samee6, Maali Alabdulhafith6,*, Yeong Hyeon Gu7, Mohammed A. Al-masni7

    CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 4225-4241, 2024, DOI:10.32604/cmc.2024.047621 - 26 March 2024

    Abstract Thyroid disorders represent a significant global health challenge with hypothyroidism and hyperthyroidism as two common conditions arising from dysfunction in the thyroid gland. Accurate and timely diagnosis of these disorders is crucial for effective treatment and patient care. This research introduces a comprehensive approach to improve the accuracy of thyroid disorder diagnosis through the integration of ensemble stacking and advanced feature selection techniques. Sequential forward feature selection, sequential backward feature elimination, and bidirectional feature elimination are investigated in this study. In ensemble learning, random forest, adaptive boosting, and bagging classifiers are employed. The effectiveness of… More >

  • Open Access

    ARTICLE

    Activated Carbon from Nipa Palm Fronds (Nypa fruticans) with H3PO4 and KOH Activators as Fe Adsorbers

    Ninis Hadi Haryanti1,*, Eka Suarso1, Tetti N. Manik1, Suryajaya1, Nurlita Sari1, Darminto2

    Journal of Renewable Materials, Vol.12, No.2, pp. 203-214, 2024, DOI:10.32604/jrm.2023.043549 - 11 March 2024

    Abstract Nipa palm is one of the non-wood plants rich in lignocellulosic content. In this study, palm fronds were converted into activated carbon, and their physical, chemical, and morphological properties were characterized. The resulting activated carbon was then applied as an adsorbent of Fe metal in peat water. The carbonization process was carried out for 60 min, followed by sintering at 400°C for 5 h with a particle size of 200 mesh. KOH and H3PO4 were used in the chemical activation process for 24 h. KOH-activated carbon contained 6.13% of moisture, 4.55% of ash, 17.02% of volatile… More > Graphic Abstract

    Activated Carbon from Nipa Palm Fronds (<i>Nypa fruticans</i>) with H<sub>3</sub>PO<sub>4</sub> and KOH Activators as Fe Adsorbers

  • Open Access

    ARTICLE

    Numerical Study on Reduction in Aerodynamic Drag and Noise of High-Speed Pantograph

    Deng Qin1, Xing Du2, Tian Li1,*, Jiye Zhang1

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.2, pp. 2155-2173, 2024, DOI:10.32604/cmes.2023.044460 - 29 January 2024

    Abstract Reducing the aerodynamic drag and noise levels of high-speed pantographs is important for promoting environmentally friendly, energy efficient and rapid advances in train technology. Using computational fluid dynamics theory and the K-FWH acoustic equation, a numerical simulation is conducted to investigate the aerodynamic characteristics of high-speed pantographs. A component optimization method is proposed as a possible solution to the problem of aerodynamic drag and noise in high-speed pantographs. The results of the study indicate that the panhead, base and insulator are the main contributors to aerodynamic drag and noise in high-speed pantographs. Therefore, a gradual… More >

  • Open Access

    ARTICLE

    Parametric Optimization of Wheel Spoke Structure for Drag Reduction of an Ahmed Body

    Huihui Zhai1, Dongqi Jiao2, Haichao Zhou2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.1, pp. 955-975, 2024, DOI:10.32604/cmes.2023.043322 - 30 December 2023

    Abstract The wheels have a considerable influence on the aerodynamic properties and can contribute up to 25% of the total drag on modern vehicles. In this study, the effect of the wheel spoke structure on the aerodynamic performance of the isolated wheel is investigated. Subsequently, the 35° Ahmed body with an optimized spoke structure is used to analyze the flow behavior and the mechanism of drag reduction. The Fluent software is employed for this investigation, with an inlet velocity of 40 m/s. The accuracy of the numerical study is validated by comparing it with experimental results obtained… More >

  • Open Access

    ARTICLE

    Numerical Study on the Effect of Vortex Generators on the Aerodynamic Drag of a High-Speed Train

    Tian Li1,2,*, Hao Liang1, Zerui Xiang2, Jiye Zhang1

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.2, pp. 463-473, 2024, DOI:10.32604/fdmp.2023.043618 - 14 December 2023

    Abstract A relatively high aerodynamic drag is an important factor that hinders the further acceleration of high-speed trains. Using the shear stress transport (SST) k-ω turbulence model, the effect of various vortex generator types on the aerodynamic characteristics of an ICE2 (Inter-city Electricity) train has been investigated. The results indicate that the vortex generators with wider triangle, trapezoid, and micro-ramp arranged on the surface of the tail car can significantly change the distribution of surface pressure and affect the vorticity intensity in the wake. This alteration effectively reduces the resistance of the tail car. Meanwhile, the micro-ramp More > Graphic Abstract

    Numerical Study on the Effect of Vortex Generators on the Aerodynamic Drag of a High-Speed Train

  • Open Access

    ARTICLE

    A Calculation Method of Double Strength Reduction for Layered Slope Based on the Reduction of Water Content Intensity

    Feng Shen1,*, Yang Zhao1, Bingyi Li1, Kai Wu2

    CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.1, pp. 221-243, 2024, DOI:10.32604/cmes.2023.029159 - 22 September 2023

    Abstract The calculation of the factor of safety (FOS) is an important means of slope evaluation. This paper proposed an improved double strength reduction method (DRM) to analyze the safety of layered slopes. The physical properties of different soil layers of the slopes are different, so the single coefficient strength reduction method (SRM) is not enough to reflect the actual critical state of the slopes. Considering that the water content of the soil in the natural state is the main factor for the strength of the soil, the attenuation law of shear strength of clayey soil… More >

  • Open Access

    ARTICLE

    Optimizing Deep Neural Networks for Face Recognition to Increase Training Speed and Improve Model Accuracy

    Mostafa Diba*, Hossein Khosravi

    Intelligent Automation & Soft Computing, Vol.38, No.3, pp. 315-332, 2023, DOI:10.32604/iasc.2023.046590 - 27 February 2024

    Abstract Convolutional neural networks continually evolve to enhance accuracy in addressing various problems, leading to an increase in computational cost and model size. This paper introduces a novel approach for pruning face recognition models based on convolutional neural networks. The proposed method identifies and removes inefficient filters based on the information volume in feature maps. In each layer, some feature maps lack useful information, and there exists a correlation between certain feature maps. Filters associated with these two types of feature maps impose additional computational costs on the model. By eliminating filters related to these categories… More >

  • Open Access

    ARTICLE

    Evaluating the Effects of Aquaculture Wastewater Irrigation with Fertilizer Reduction on Greenhouse Tomato Production, Economic Benefits and Soil Nitrogen Characteristics

    Hang Guo1,2,3, Linxian Liao1,2,3, Zhenhao Zheng4, Junzeng Xu1,2,3,*, Qi Wei1,2,3, Peng Chen1,2,3, Kechun Wang1,2,3

    Phyton-International Journal of Experimental Botany, Vol.92, No.12, pp. 3291-3304, 2023, DOI:10.32604/phyton.2023.044051 - 28 December 2023

    Abstract

    The utilization of aquaculture wastewater as irrigation is an effective way to recycle and reuse water and nitrogen fertilizer resources because it contains numerous nutrients. However, it is still unclear that the pattern of substituting aquaculture wastewater irrigation for fertilizer supplementing is conducive to improving the soil nitrogen status, fruit yield and water-fertilizer use efficiency for tomato production. In this context, the experiment was intended to establish the appropriate irrigation regime of aquaculture wastewater in tomato production for freshwater replacement and fertilizer reduction to ensure good yields. Pot experiments were conducted with treatments as farmers

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