Yongbing Li^1,*, Yunwu Ma¹, Yujun Xia¹, Ming Lou¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.4, pp. 1-1, 2024, DOI:10.32604/icces.2024.012602

Abstract The implementation of lightweight materials and structures in automotive body manufacturing is a strategic approach to improve fuel efficiency of energy-efficient vehicles and driving range of new energy vehicles. However, high specific strength low-ductility light metals (like 7xxx aluminum, magnesium and cast aluminum), ultra-high strength steels, high-stiffness profile structures and their mixed use poses a big challenge to existing commercial spot joining processes, such as resistance spot welding and self-piercing riveting. In this talk, the challenges which new lightweight materials and structures pose to spot joining process will be presented, the bottleneck of the existing More >

Yeye Liu¹, Leilei Zhang^1,*, Ruonan Zhang¹, Siqi Shao¹, Lina Sun¹, Xinyi Wan¹, Tiantian Wang¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.012576

Abstract Superior thermal insulating and fire-retardant ceramic membranes are urgently demanded in the aerospace, construction and chemical engineering industries. However, the generic characteristics of ceramic membranes, such as brittleness, structural collapse and crystallization-induced pulverization behavior, present a great plague to their practical applications. Herein, we report a highly flexible, mechanically stable, fire retardant and high-temperature-resistant ceramic membrane based on the interlocked Si₃N₄ nanowires formed by the precursor pyrolysis method. The Si₃N₄ nanowires membrane (SNM) has excellent high temperature resistance under alcohol lamp and butane spray lance. The thermal insulation with a thermal conductivity as low as 0.056… More >

Yijun Gao^1,2, Yong Wang^1,*, Qing Na¹, Jiawei Zhang¹, Aixiang Wu¹

FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.11, pp. 2443-2458, 2024, DOI:10.32604/fdmp.2024.051385 - 28 October 2024

Abstract Filling methods in the mining industry can maximize the recovery of mineral resources and protect the underground and surface environments. In recent years, such methods have been widely used in metal mines where pipeline transportation typically plays a decisive role in the safety and stability of the entire filling system. Because the filling slurry contains a large percentage of solid coarse particles, the involved pipeline is typically eroded and often damaged during such a process. A possible solution is the so-called nesting repair technology. In the present study, nesting a 127 mm outer diameter pipeline… More >

SHAIL RAKESH MODI, TERRICK ANDEY^*

Oncology Research, Vol.32, No.11, pp. 1709-1721, 2024, DOI:10.32604/or.2024.053972 - 16 October 2024

Abstract Objectives: EGFR tyrosine kinase inhibitor (EGFR-TKI) therapies such as erlotinib and gefitinib are approved for the treatment of non-small cell lung cancer (NSCLC). However, the high incidence of acquired resistance to these EGFR-TKIs may preclude their effectiveness. Piperlongumine (PPL), an extract from the long pepper fruit (Piper longum), has been shown to possess anticancer properties. The purpose of the study was to investigate piperlongumine as an anticancer agent and to study a combination treatment approach with EGFR-TKIs against lung cancer cells. Methods: Anticancer efficacy of PPL, erlotinib (ERL), gefitinib (GEF), and cisplatin (CIS) were investigated in… More >

Mingzhi Chen¹, Zhandong Wang², Guifang Sun^1,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.29, No.4, pp. 1-1, 2024, DOI:10.32604/icces.2024.012203

Abstract Marine environments pose severe corrosion challenges to underwater equipment, thereby leading to significant risks and demanding immediate in-situ restoration. Here we developed an underwater laser directed energy deposition (UDMD) technique to repair the E690 steel and enhance its corrosion resistance. Systematic investigations about the underwater pressure (P) and 316L stainless steel (SS316L) coatings on the microstructure, mechanical properties, and corrosion resistance of the repaired E690 steel were conducted. Results show that water cooling can refine grain, promote the formation of lath martensite, and increase dislocation density. No obvious relationship between the pressure and microstructure evolution… More >

Fatima-Ezzahra Soussani^1,2,3, Youssef Ait Rahou^1,2,4, Chayma Ikan^1,2, Allal Douira³, Rachid Benkirane³, Essaid Ait Barka⁵, Rachid Lahlali^6,*, Abdelilah Meddich^1,2,7,*

Phyton-International Journal of Experimental Botany, Vol.93, No.9, pp. 2415-2438, 2024, DOI:10.32604/phyton.2024.055050 - 30 September 2024

Abstract This study assesses the effectiveness of using arbuscular mycorrhizal fungi (M) and compost applied alone or in combination (vs. conventional chemical fertilizer application (NPK)) on tomato resistance to vascular wilt caused by Verticillium dahliae. In this study, ten treatments were applied: (1) Control (2) M: Rhizophagus irregularis (3) C: Compost (4) MC: The combination of M and compost (5) NPK: conventional chemical fertilizer (6) V: plants infected with V. dahliae (7) MV: plants infected with a conidial suspension of V. dahliae and M, (8) CV: The combination of compost and V. dahliae, (9) MCV: The combination of M, compost and V. dahliae,… More >

XIAOXIAO HE¹, XUEQING ZHOU², JINPENG ZHANG², MINGFEI ZHANG², DANHONG ZENG², HENG ZHANG¹, SHUCAI YANG^2,*

BIOCELL, Vol.48, No.9, pp. 1331-1341, 2024, DOI:10.32604/biocell.2024.052625 - 04 September 2024

Abstract Objectives: This investigation aimed to elucidate the inhibitory impact of apatinib on the multidrug resistance of liver cancer both in vivo and in vitro. Methods: To establish a Hep3B/5-Fu resistant cell line, 5-Fu concentrations were gradually increased in the culture media. Hep3B/5-Fu cells drug resistance and its alleviation by apatinib were confirmed via flow cytometry and Cell Counting Kit 8 (CCK8) test. Further, Nuclear factor kappa B (NF-κB) siRNA was transfected into Hep3B/5-Fu cells to assess alterations in the expression of multidrug resistance (MDR)-related genes and proteins. Nude mice were injected with Hep3B/5-Fu cells to establish subcutaneous… More >

Lijun Zhang, Ying Liu^*, Yushou Ma^*, Xinyou Wang

Phyton-International Journal of Experimental Botany, Vol.93, No.8, pp. 1913-1941, 2024, DOI:10.32604/phyton.2024.052621 - 30 August 2024

Abstract Perennial grasses have developed intricate mechanisms to adapt to diverse environments, enabling their resistance to various biotic and abiotic stressors. These mechanisms arise from strong natural selection that contributes to enhancing the adaptation of forage plants to various stress conditions. Methods such as antisense RNA technology, CRISPR/Cas9 screening, virus-induced gene silencing, and transgenic technology, are commonly utilized for investigating the stress response functionalities of grass genes in both warm-season and cool-season varieties. This review focuses on the functional identification of stress-resistance genes and regulatory elements in grasses. It synthesizes recent studies on mining functional genes, regulatory More >

Dandan Yuan, Ju Cai, Tao Zhang, Sisi Wang, Xiuliu Yang, Yan Li^*

Phyton-International Journal of Experimental Botany, Vol.93, No.8, pp. 1875-1896, 2024, DOI:10.32604/phyton.2024.052190 - 30 August 2024

Abstract The WRKY transcription factor gene family is one of the unique gene families in plants. It plays an important role in response to abiotic stresses such as cold and drought, hormone signal transduction, regulation of biosynthesis, leaf senescence seed germination, etc. However, little information is available about WRKY transcription factors in Verbena bonariensis. In this study, 70 VbWRKY genes were identified from the whole genome. The phylogenetic analysis of the WRKY gene family in V. bonariensis and Arabidopsis shows that the WRKY genes in V. bonariensis can be divided into three groups: I, II, and III, which contain 13, 47, and… More >

SHAN JIANG^1,2, XIUFENG LIN², YANFEI CHEN³, XINNING LI³, JIALI KANG^1,4,*

BIOCELL, Vol.48, No.8, pp. 1265-1273, 2024, DOI:10.32604/biocell.2024.051478 - 02 August 2024

Abstract Background: Despite improvements in objective response rates to cisplatin-based combination chemotherapy, the majority of advanced ovarian cancer remains suboptimal, resulting in poor survival. it has been found that non-coding RNAs (ncRNAs) not only participate in the transmission of signals between various cells but also participate in tumor immunity and anti-tumor immune responses, thereby regulating tumor occurrence and development. However, the function and detailed mechanism of ultraconserved RNA (ucRNA) in ovarian cancer chemoresistance is still unclear. Methods: Western blotting assay, Quantitative real-time PCR analysis (qPCR), and Kaplan-Meier Plotter analysis were performed to analyze the expression and prognosis… More >