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  • Open Access

    ARTICLE

    Development of a High-Temperature Thixotropic Cement Slurry System

    Ping Lv1, Jiufei Liu2, Mengran Xu3,*, Hui Tian3,4, Huajie Liu3, Yuhuan Bu3, Zhuang Cai3, Junfeng Qu5

    FDMP-Fluid Dynamics & Materials Processing, Vol.19, No.11, pp. 2907-2921, 2023, DOI:10.32604/fdmp.2023.029304

    Abstract Cementing carbonate reservoirs is generally a difficult task. The so-called thixotropic cement slurry has gained considerable attention in this regard as it can help to fix some notable problems. More precisely, it can easily fill the leakage layer; moreover, its gelling strength can grow rapidly when pumping stops, thereby increasing the resistance to gas channeling, effectively preventing this undesired phenomenon in many cases. High-temperature thixotropic cement slurry systems, however, are still in an early stage of development and additional research is needed to make them a viable option. In the present study, using a self-developed composite high-temperature thixotropic additive as… More >

  • Open Access

    ARTICLE

    Evaluation of Pre-Harvest Sprouting (PHS) Resistance and Screening of High-Quality Varieties from Thirty-Seven Quinoa (Chenopodium quinoa Willd.) Resources in Chengdu Plain

    Xin Pan, Ya Gao, Fang Zeng, Chunmei Zheng, Wenxuan Ge, Yan Wan, Yanxia Sun, Xiaoyong Wu*

    Phyton-International Journal of Experimental Botany, Vol.92, No.10, pp. 2921-2936, 2023, DOI:10.32604/phyton.2023.029853

    Abstract Pre-harvest sprouting (PHS) will have a serious effect both on the yield and quality of quinoa (Chenopodium quinoa Willd.). It is crucial to select and breed quinoa varieties with PHS resistance and excellent agronomic traits for guidance production and utilization of quinoa. A comprehensive evaluation of the PHS resistance and agronomic traits of 37 species of quinoa resources was conducted in Chengdu Plain. The evaluation used various methods, including grain germination rate (GR), grain germination index (GI), total spike germination rate (SR), total grain germination index (SI), grey correlation analysis (GCA), cluster analysis and correlation analysis. Results showed significant differences… More >

  • Open Access

    ARTICLE

    Hemodynamic Profiling Using a Cardiac Index–Systemic Vascular Resistance Plot in Patients with Fontan Circulation

    Yuki Kawasaki1,*, Takeshi Sasaki1, Daisuke Kobayashi2

    Congenital Heart Disease, Vol.18, No.4, pp. 431-445, 2023, DOI:10.32604/chd.2023.030910

    Abstract Background: Elevated Fontan pressure (FP) alone cannot fully predict clinical outcomes. We hypothesized that hemodynamic profiling using a cardiac index (CI)-systemic vascular resistance (SVR) plot could characterize clinical features and predict the prognosis of post-Fontan patients. Methods: We included post-Fontan patients who underwent cardiac catheterization at age < 10 years. Patients were classified into four categories: A, CI  ≥ 3, SVR index (SVRI) ≥ 20; B, CI < 3, SVRI ≥ 20; C, CI ≥ 3, SVRI < 20; and D, CI < 3, SVRI < 20. The primary outcome was freedom from the combined endpoint: new onset of protein-losing enteropathy or plastic bronchitis, heart transplant, and death. Clinical and hemodynamic variables and freedom from… More > Graphic Abstract

    Hemodynamic Profiling Using a Cardiac Index–Systemic Vascular Resistance Plot in Patients with Fontan Circulation

  • Open Access

    PROCEEDINGS

    Multiscale Structural Design and Fracture Control of High-Performance Biomimetic Materials

    Kaijin Wu1,*, Yong Ni1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.26, No.3, pp. 1-2, 2023, DOI:10.32604/icces.2023.09028

    Abstract Bioinspired architectural design for composites with much higher impact-resistance and fracture-resistance than that of individual constituent remains a major challenge for engineers and scientists. Inspired by the survival war between the mantis shrimps and abalones, we develop multiscale mechanical methods to design structures and control fractures in high-performance biomimetic materials. The first point is the optimization design of impact-resistant nacre-like materials [1-4]. By a combination of simulation, additive manufacturing, and drop tower testing we revealed that, at a critical interfacial strength or a critical prestress, the competition between intralayer cracks and interlayer delamination, or the synergistic effect between the prestress-enhanced… More >

  • Open Access

    ARTICLE

    Developing a Breast Cancer Resistance Protein Substrate Prediction System Using Deep Features and LDA

    Mehdi Hassan1,2, Safdar Ali3, Jin Young Kim2,*, Muhammad Sanaullah4, Hani Alquhayz5, Khushbakht Safdar6

    CMC-Computers, Materials & Continua, Vol.76, No.2, pp. 1643-1663, 2023, DOI:10.32604/cmc.2023.038578

    Abstract Breast cancer resistance protein (BCRP) is an important resistance protein that significantly impacts anticancer drug discovery, treatment, and rehabilitation. Early identification of BCRP substrates is quite a challenging task. This study aims to predict early substrate structure, which can help to optimize anticancer drug development and clinical diagnosis. For this study, a novel intelligent approach-based methodology is developed by modifying the ResNet101 model using transfer learning (TL) for automatic deep feature (DF) extraction followed by classification with linear discriminant analysis algorithm (TLRNDF-LDA). This study utilized structural fingerprints, which are exploited by DF contrary to conventional molecular descriptors. The proposed in… More >

  • Open Access

    ARTICLE

    Blue LED promotes the chemosensitivity of human hepatoma to Sorafenib by inducing DNA damage

    TONG WANG1,4,#, JINHUAN HONG1,5,#, JIAJIE XIE1,5, QIAN LIU4, JINRUI YUE1,5, XUTING HE1,5, SHIYU GE4, TAO LI4, GUOXIN LIU4, BENZHI CAI1,3,5, LINQIANG LI2,*, YE YUAN1,3,5,*

    BIOCELL, Vol.47, No.8, pp. 1811-1820, 2023, DOI:10.32604/biocell.2023.029120

    Abstract Background: Phototherapies based on sunlight, infrared, ultraviolet, visible, and laser-based treatments present advantages like high curative effects, small invasion, and negligible adverse reactions in cancer treatment. We aimed to explore the potential therapeutic effects of blue light emitting diode (LED) in human hepatoma cells and decipher the underlying cellular and molecular mechanisms. Methods: Wound healing and transwell assays were employed to probe the inhibition of the invasion and migration of hepatocellular carcinoma cells in the presence of blue LED. The sphere-forming test was used to evaluate the effect of LED blue light irradiation on cancer stem cell properties. Immunofluorescence and… More > Graphic Abstract

    Blue LED promotes the chemosensitivity of human hepatoma to Sorafenib by inducing DNA damage

  • Open Access

    ARTICLE

    Preliminary Study on the Treatment Efficiency of Pasteurized Lime Thermal Alkaline Hydrolysis for Excess Activated Sludge and Reduction of Tetracycline Resistance Genes

    Maoxia Chen1,2,*, Qixuan Zhou1, Jiayue Zhang1, Jiaoyang Li1, Wei Zhang1, Huan Liu1

    Journal of Renewable Materials, Vol.11, No.10, pp. 3711-3723, 2023, DOI:10.32604/jrm.2023.027826

    Abstract Thermal alkaline hydrolysis is a common pretreatment method for the utilization of excess activated sludge (EAS). Owing to strict environment laws and need for better energy utilization, new methods were developed in this study to improve the efficiency of pretreatment method. Direct thermal hydrolysis (TH), pasteurized thermal hydrolysis (PTH), and alkaline pasteurized thermal hydrolysis (PTH + CaO and PTH + NaOH) methods were used to treat EAS. Each method was compared and analyzed in terms of dissolution in ammonium nitrogen (NH4 + -N) and soluble COD (SCOD) in EAS. Furthermore, the removal of tetracycline resistance genes (TRGs) and class 1… More >

  • Open Access

    ARTICLE

    NUMERICAL STUDY OF THE GASKET THERMAL CONDUCTIVITY EFFECT ON THE THERMAL CONTACT RESISTANCE BETWEEN TWO SOLIDS IN CONTACT

    Rachid Chadoulia,b,*, Frédéric Lebona, Iulian Rosua , Mohammed Makhloufb

    Frontiers in Heat and Mass Transfer, Vol.8, pp. 1-6, 2017, DOI:10.5098/hmt.8.30

    Abstract In this paper, a numerical model investigating the impact of gasket thermal quality on the reduction in the thermal contact resistance (TCR) between two solids is presented and validated analytically. The model proposed is a 2D steady state model. The thermal conductivity of the solid materials ranges from 20 to 390 W/m·K, and the gasket thermal conductivity ranges from 0.16W/m·K (TC of rubber) to and 5W/m·K (TC of thermal paste). As expected, the results obtained clearly confirm that the gasket significantly improves the heat transfer between two solids in contact, and in particular that the TCR is decreased with increasing… More >

  • Open Access

    ARTICLE

    PERFORMANCE OF ORTHOTROPIC ANNULAR FINS HAVING CONTACT RESISTANCE

    Harpreet Kaur Aasi, Vivek Kumar Gaba, Anil Kumar Tiwari, Shubhankar Bhowmick*

    Frontiers in Heat and Mass Transfer, Vol.8, pp. 1-6, 2017, DOI:10.5098/hmt.8.15

    Abstract Due to low density and low coefficient of thermal expansion, orthotropic materials, namely, the polymer matrix composites are finding their way in many of the engineering application. The present study investigates the performance of the orthotropic annular fin. The thermal conductivity along radial and axial direction is governed by the thermal conductivity ratio (K), which is an important parameter for orthotropic annular fin. The work then numerically examines in two dimensions, the thermal performance of the annular fin at different thermal conductivity ratio (K) for the rectangular profile using the finite difference method. Different convective heat transfer coefficient are considered… More >

  • Open Access

    ARTICLE

    EFFECTIVE THERMAL RESISTANCE COMPARISON OF AEROGEL AND MULTI-LAYER INSULATION AS RADIATIVE BARRIERS USING THE SINGLE-SIDED GUARDED HOT PLATE METHOD

    Kevin W. Irick*

    Frontiers in Heat and Mass Transfer, Vol.8, pp. 1-7, 2017, DOI:10.5098/hmt.8.2

    Abstract The Single-sided Guarded Hot Plate Method for Comparative Testing of Thermal Radiation Barriers in Vacuum was used to evaluate the performance of a variety of aerogel insulation specimens manufactured by Aspen Aerogels® against one another and against multi-layer insulation (MLI). Testing at the Air Force Research Laboratory (AFRL) shows that the effective thermal resistance, Re, of all tested aerogel specimens are virtually bounded by the performance of 5-layer and 10-layer MLI specimens over a mean specimen temperature, Tm, range of about 270K to 315K. More >

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