Jiao Li^1,2, Nurhayu Ab Rahman^1,3, Suharni Mohamad¹, Guang Yang⁴, Caixia Zhao^2,*

Oncology Research, Vol.33, No.9, pp. 2263-2278, 2025, DOI:10.32604/or.2025.065911 - 28 August 2025

Abstract Objectives: Checkpoint inhibitors have significantly improved outcomes in a number of malignancies. To determine the most effective course of treatment for head and neck squamous cell carcinoma (HNSCC), this systematic review evaluated the efficacy of several therapeutic approaches based on immune checkpoint inhibitors (ICIs). Methods: A comprehensive evaluation of the literature was conducted, looking at randomized controlled trials (RCTs) that were published in Embase, PubMed, and the Cochrane Central Register of Controlled Trials since database establishment. The risk of bias of the enrolled studies was analyzed using The Review Manager (RevMan) 5.4. Using network meta-analyses… More >

Saranya Velmurugan¹, Dapkupar Wankhar², Vijayalakshmi Paramasivan³, Gowtham Kumar Subbaraj^1,*

BIOCELL, Vol.49, No.8, pp. 1363-1390, 2025, DOI:10.32604/biocell.2025.065891 - 29 August 2025

Abstract Cancer rates are increasing globally, making it more urgent than ever to enhance research and treatment strategies. This study aims to investigate how innovative technology and integrated multi-omics techniques could help improve cancer diagnosis, knowledge, and therapy. A complete literature search was undertaken using PubMed, Elsevier, Google Scholar, ScienceDirect, Embase, and NCBI. This review examined the articles published from 2010 to 2025. Relevant articles were found using keywords and selected using inclusion criteria New sequencing methods, like next-generation sequencing and single-cell analysis, have transformed our ability to study tumor complexity and genetic mutations, paving the… More >

Zongyu Jie^1,2, Chao Dang^1,2,*, Qingliang Meng ^3,4

Frontiers in Heat and Mass Transfer, Vol.23, No.4, pp. 1053-1089, 2025, DOI:10.32604/fhmt.2025.066792 - 29 August 2025

Abstract With the increasing miniaturization of systems and surging demand for power density, accurate prediction and control of two-phase flow pressure drop have become a core challenge restricting the performance of microchannel heat exchangers. Pressure drop, a critical hydraulic characteristic, serves as both a natural constraint for cooling systems and determines the power required to pump the working fluid through microchannels. This paper reviews the characteristics, prediction models, and optimization measures of two-phase flow pressure drop for low-boiling-point working fluids in microchannels. It systematically analyzes key influencing factors such as fluid physical properties, operating conditions, channel… More >

Hitesh Mohapatra^*

CMC-Computers, Materials & Continua, Vol.85, No.1, pp. 221-247, 2025, DOI:10.32604/cmc.2025.068338 - 29 August 2025

Abstract Fault tolerance is essential for reliable and sustainable smart city infrastructure. Interconnected IoT systems must function under frequent faults, limited resources, and complex conditions. Existing research covers various fault-tolerant methods. However, current reviews often lack system-level critique and multidimensional analysis. This study provides a structured review of fault tolerance strategies across layered IoT architectures in smart cities. It evaluates fault detection, containment, and recovery techniques using specific metrics. These include fault visibility, propagation depth, containment score, and energy-resilience trade-offs. The analysis uses comparative tables, architecture-aware discussions, and conceptual plots. It investigates the impact of fault… More >

Junhui Hua¹, Junyuan Xiong², Bo Xu^1,*, Chong Wang¹, Qingyuan Wang¹

CMC-Computers, Materials & Continua, Vol.85, No.1, pp. 65-88, 2025, DOI:10.32604/cmc.2025.068226 - 29 August 2025

Abstract Shape memory alloys (SMAs) and shape memory ceramics (SMCs) exhibit high recovery ability due to the martensitic transformation, which complicates the fracture mechanism of SMAs and SMCs. The phase field method, as a powerful numerical simulation tool, can efficiently resolve the microstructural evolution, multi-field coupling effects, and fracture behavior of SMAs and SMCs. This review begins by presenting the fundamental theoretical framework of the fracture phase field method as applied to SMAs and SMCs, covering key aspects such as the phase field modeling of martensitic transformation and brittle fracture. Subsequently, it systematically examines the phase More >

Apoorav Sharma¹, Ayush Dogra^2,*, Bhawna Goyal³, Archana Saini², Vinay Kukreja²

CMC-Computers, Materials & Continua, Vol.85, No.1, pp. 367-481, 2025, DOI:10.32604/cmc.2025.066481 - 29 August 2025

Abstract To enable proper diagnosis of a patient, medical images must demonstrate no presence of noise and artifacts. The major hurdle lies in acquiring these images in such a manner that extraneous variables, causing distortions in the form of noise and artifacts, are kept to a bare minimum. The unexpected change realized during the acquisition process specifically attacks the integrity of the image’s quality, while indirectly attacking the effectiveness of the diagnostic process. It is thus crucial that this is attended to with maximum efficiency at the level of pertinent expertise. The solution to these challenges… More >

Yifan Li¹, Congzhe Zhu¹, Zhihan Lyu^2,*, Bin Yang^1,3,*, Thomas Olofsson³

Energy Engineering, Vol.122, No.9, pp. 3525-3553, 2025, DOI:10.32604/ee.2025.067902 - 26 August 2025

Abstract The growth of computing power in data centers (DCs) leads to an increase in energy consumption and noise pollution of air cooling systems. Chip-level cooling with high-efficiency coolant is one of the promising methods to address the cooling challenge for high-power devices in DCs. Hybrid nanofluid (HNF) has the advantages of high thermal conductivity and good rheological properties. This study summarizes the numerical investigations of HNFs in mini/micro heat sinks, including the numerical methods, hydrothermal characteristics, and enhanced heat transfer technologies. The innovations of this paper include: (1) the characteristics, applicable conditions, and scenarios of… More >

Souha Mansour^1,2,*, Amandine Viretto^1,2, Marie-France Thevenon^1,2,*, Loïc Brancheriau^1,2

Journal of Renewable Materials, Vol.13, No.8, pp. 1547-1586, 2025, DOI:10.32604/jrm.2025.02024-0078 - 22 August 2025

Abstract The use of agricultural residues in biocomposite production has gained increasing attention, driven by several benefits. Converting agricultural by-products into bio-based materials within a circular economy represents a sustainable strategy to mitigate lignocellulosic waste, reduce reliance on fossil resources, and lower environmental pollution. This approach also creates economic opportunities for rural African communities by generating diverse income sources for workers in collection, processing, and manufacturing. As a result, the integration of agricultural residues into biocomposites production not only addresses environmental concerns but also fosters economic growth and supports rural development. In this review, five biomasses… More > Graphic Abstract

Kelvin Kang Wee Tang^1,*, Muhammad Hafiz Mohd Yatim¹, Norhadija Darwin², Wan Anom Wan Aris¹, Sim Ching Yen³, Nurfazira Mohamed Fadil³

Revue Internationale de Géomatique, Vol.34, pp. 587-602, 2025, DOI:10.32604/rig.2025.065583 - 06 August 2025

Abstract The integration of Unmanned Aerial Vehicles (UAVs) and Uncrewed Surface Vehicles (USVs) has revolutionized topographic and bathymetric mapping, significantly enhancing the accuracy and efficiency of geospatial data acquisition processes. This innovative approach synergistically combines terrestrial data collected by UAVs with underwater data obtained through USVs, culminating in the creation of unified high-resolution Digital Elevation Models (DEMs) of the river basin region represents a vital step toward understanding the dynamic interactions between land and water bodies. Hence, the seamless Topo-Bathymetric Elevation Model offers a detailed perspective of the river system, supporting informed decision-making in addressing sediment… More >

Ibrahim T. Teke^1,2, Ahmet H. Ertas^2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.1, pp. 201-237, 2025, DOI:10.32604/cmes.2025.066644 - 31 July 2025

Abstract Fatigue failure continues to be a significant challenge in designing structural and mechanical components subjected to repeated and complex loading. While earlier studies mainly examined material properties and how stress affects lifespan, this review offers the first comprehensive, multiscale comparison of strategies that optimize geometry to improve fatigue performance. This includes everything from microscopic features like the shape of graphite nodules to large-scale design elements such as fillets, notches, and overall structural layouts. We analyze and combine various methods, including topology and shape optimization, the ability of additive manufacturing to fine-tune internal geometries, and reliability-based More >