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  • Open Access

    REVIEW

    Research progress on cancer-associated fibroblasts in osteosarcoma

    LIWEN FENG1,2,#,*, YUTING CHEN3,#, WENYI JIN4

    Oncology Research, Vol.33, No.5, pp. 1091-1103, 2025, DOI:10.32604/or.2024.054207 - 18 April 2025

    Abstract Osteosarcoma (OS) is a prevalent primary bone malignancy with limited treatment options. Therefore, it is imperative to investigate and understand the mechanisms underlying OS pathogenesis. Cancer-associated fibroblasts (CAFs) are markedly abundant in tumor stromal cells and are essentially involved in the modulation of tumor occurrence and development. In recent years, CAFs have become a hotspot as researchers aim to elucidate CAF mechanisms that regulate tumor progression. However, most studies on CAFs are limited to a few common cancers, and their association with OS remains elusive. This review describes the role and current knowledge of CAFs More >

  • Open Access

    ARTICLE

    Barber Optimization Algorithm: A New Human-Based Approach for Solving Optimization Problems

    Tareq Hamadneh1, Belal Batiha2, Omar Alsayyed3, Widi Aribowo4, Zeinab Montazeri5, Mohammad Dehghani5,*, Frank Werner6,*, Haider Ali7, Riyadh Kareem Jawad8, Ibraheem Kasim Ibraheem9, Kei Eguchi10

    CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 2677-2718, 2025, DOI:10.32604/cmc.2025.064087 - 16 April 2025

    Abstract In this study, a completely different approach to optimization is introduced through the development of a novel metaheuristic algorithm called the Barber Optimization Algorithm (BaOA). Inspired by the human interactions between barbers and customers, BaOA captures two key processes: the customer’s selection of a hairstyle and the detailed refinement during the haircut. These processes are translated into a mathematical framework that forms the foundation of BaOA, consisting of two critical phases: exploration, representing the creative selection process, and exploitation, which focuses on refining details for optimization. The performance of BaOA is evaluated using 52 standard… More >

  • Open Access

    COMMENTARY

    From Data to Discovery: How AI-Driven Materials Databases Are Reshaping Research

    Yaping Qi1,*, Weijie Yang2,*

    CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 1555-1559, 2025, DOI:10.32604/cmc.2025.064061 - 16 April 2025

    Abstract AI-driven materials databases are transforming research by integrating experimental and computational data to enhance discovery and optimization. Platforms such as Digital Catalysis Platform (DigCat) and Dynamic Database of Solid-State Electrolyte (DDSE) demonstrate how machine learning and predictive modeling can improve catalyst and solid-state electrolyte development. These databases facilitate data standardization, high-throughput screening, and cross-disciplinary collaboration, addressing key challenges in materials informatics. As AI techniques advance, materials databases are expected to play an increasingly vital role in accelerating research and innovation. More >

  • Open Access

    ARTICLE

    An Enhanced Fuzzy Routing Protocol for Energy Optimization in the Underwater Wireless Sensor Networks

    Mehran Tarif1, Mohammadhossein Homaei2,*, Amir Mosavi3,4,5

    CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 1791-1820, 2025, DOI:10.32604/cmc.2025.063962 - 16 April 2025

    Abstract Underwater Wireless Sensor Networks (UWSNs) are gaining popularity because of their potential uses in oceanography, seismic activity monitoring, environmental preservation, and underwater mapping. Yet, these networks are faced with challenges such as self-interference, long propagation delays, limited bandwidth, and changing network topologies. These challenges are coped with by designing advanced routing protocols. In this work, we present Under Water Fuzzy-Routing Protocol for Low power and Lossy networks (UWF-RPL), an enhanced fuzzy-based protocol that improves decision-making during path selection and traffic distribution over different network nodes. Our method extends RPL with the aid of fuzzy logic More >

  • Open Access

    ARTICLE

    An Adaptive Cooperated Shuffled Frog-Leaping Algorithm for Parallel Batch Processing Machines Scheduling in Fabric Dyeing Processes

    Lianqiang Wu, Deming Lei*, Yutong Cai

    CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 1771-1789, 2025, DOI:10.32604/cmc.2025.063944 - 16 April 2025

    Abstract Fabric dyeing is a critical production process in the clothing industry and heavily relies on batch processing machines (BPM). In this study, the parallel BPM scheduling problem with machine eligibility in fabric dyeing is considered, and an adaptive cooperated shuffled frog-leaping algorithm (ACSFLA) is proposed to minimize makespan and total tardiness simultaneously. ACSFLA determines the search times for each memeplex based on its quality, with more searches in high-quality memeplexes. An adaptive cooperated and diversified search mechanism is applied, dynamically adjusting search strategies for each memeplex based on their dominance relationships and quality. During the… More >

  • Open Access

    ARTICLE

    Bidirectional LSTM-Based Energy Consumption Forecasting: Advancing AI-Driven Cloud Integration for Cognitive City Energy Management

    Sheik Mohideen Shah1, Meganathan Selvamani1, Mahesh Thyluru Ramakrishna2,*, Surbhi Bhatia Khan3,4,5, Shakila Basheer6, Wajdan Al Malwi7, Mohammad Tabrez Quasim8

    CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 2907-2926, 2025, DOI:10.32604/cmc.2025.063809 - 16 April 2025

    Abstract Efficient energy management is a cornerstone of advancing cognitive cities, where AI, IoT, and cloud computing seamlessly integrate to meet escalating global energy demands. Within this context, the ability to forecast electricity consumption with precision is vital, particularly in residential settings where usage patterns are highly variable and complex. This study presents an innovative approach to energy consumption forecasting using a bidirectional Long Short-Term Memory (LSTM) network. Leveraging a dataset containing over two million multivariate, time-series observations collected from a single household over nearly four years, our model addresses the limitations of traditional time-series forecasting… More >

  • Open Access

    ARTICLE

    Single Qubit Quantum Logistic-Sine XYZ-Rotation Maps: An Ultra-Wide Range Dynamics for Image Encryption

    De Rosal Ignatius Moses Setiadi1,*, T. Sutojo1, Supriadi Rustad1, Muhamad Akrom1, Sudipta Kr Ghosal2, Minh T. Nguyen3, Arnold Adimabua Ojugo4

    CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 2161-2188, 2025, DOI:10.32604/cmc.2025.063729 - 16 April 2025

    Abstract Data security has become a growing priority due to the increasing frequency of cyber-attacks, necessitating the development of more advanced encryption algorithms. This paper introduces Single Qubit Quantum Logistic-Sine XYZ-Rotation Maps (SQQLSR), a quantum-based chaos map designed to generate one-dimensional chaotic sequences with an ultra-wide parameter range. The proposed model leverages quantum superposition using Hadamard gates and quantum rotations along the X, Y, and Z axes to enhance randomness. Extensive numerical experiments validate the effectiveness of SQQLSR. The proposed method achieves a maximum Lyapunov exponent (LE) of ≈55.265, surpassing traditional chaotic maps in unpredictability. The bifurcation analysis… More >

  • Open Access

    ARTICLE

    An Enhanced VIKOR and Its Revisit for the Manufacturing Process Application

    Ting-Yu Lin1, Kuo-Chen Hung2,*, Josef Jablonsky3, Kuo-Ping Lin1

    CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 1901-1927, 2025, DOI:10.32604/cmc.2025.063543 - 16 April 2025

    Abstract VlseKriterijumska Optimizacija I Kompromisno Resenje (VIKOR) has been developed and applied for over twenty-five years, gaining recognition as a prominent multi-criteria decision-making (MCDM) method. Over this period, numerous studies have explored its applications, conducted comparative analyses, integrated it with other methods, and proposed various modifications to enhance its performance. This paper aims to delve into the fundamental principles and objectives of VIKOR, which aim to maximize group utility and minimize individual regret simultaneously. However, this study identifies a significant limitation in the VIKOR methodology: its process amplifies the weight of individual regret, and the calculated… More >

  • Open Access

    ARTICLE

    UltraSegNet: A Hybrid Deep Learning Framework for Enhanced Breast Cancer Segmentation and Classification on Ultrasound Images

    Suhaila Abuowaida1,*, Hamza Abu Owida2, Deema Mohammed Alsekait3,*, Nawaf Alshdaifat4, Diaa Salama AbdElminaam5,6, Mohammad Alshinwan4

    CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 3303-3333, 2025, DOI:10.32604/cmc.2025.063470 - 16 April 2025

    Abstract Segmenting a breast ultrasound image is still challenging due to the presence of speckle noise, dependency on the operator, and the variation of image quality. This paper presents the UltraSegNet architecture that addresses these challenges through three key technical innovations: This work adds three things: (1) a changed ResNet-50 backbone with sequential 3 convolutions to keep fine anatomical details that are needed for finding lesion boundaries; (2) a computationally efficient regional attention mechanism that works on high-resolution features without using a transformer’s extra memory; and (3) an adaptive feature fusion strategy that changes local and… More >

  • Open Access

    REVIEW

    Blockchain Integration in IoT: Applications, Opportunities, and Challenges

    Mozhgan Gholami1, Ali Ghaffari1,2,3,*, Nahideh Derakhshanfard1, Nadir iBRAHIMOĞLU4, Ali Asghar Pourhaji Kazem2

    CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 1561-1605, 2025, DOI:10.32604/cmc.2025.063304 - 16 April 2025

    Abstract The Internet has been enhanced recently by blockchain and Internet of Things (IoT) networks. The Internet of Things is a network of various sensor-equipped devices. It gradually integrates the Internet, sensors, and cloud computing. Blockchain is based on encryption algorithms, which are shared database technologies on the Internet. Blockchain technology has grown significantly because of its features, such as flexibility, support for integration, anonymity, decentralization, and independent control. Computational nodes in the blockchain network are used to verify online transactions. However, this integration creates scalability, interoperability, and security challenges. Over the last decade, several advancements… More >

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