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  • Open Access

    ARTICLE

    Modeling Geometrically Nonlinear FG Plates: A Fast and Accurate Alternative to IGA Method Based on Deep Learning

    Se Li1, Tiantang Yu1,*, Tinh Quoc Bui2

    CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.3, pp. 2793-2808, 2024, DOI:10.32604/cmes.2023.030278

    Abstract Isogeometric analysis (IGA) is known to show advanced features compared to traditional finite element approaches. Using IGA one may accurately obtain the geometrically nonlinear bending behavior of plates with functional grading (FG). However, the procedure is usually complex and often is time-consuming. We thus put forward a deep learning method to model the geometrically nonlinear bending behavior of FG plates, bypassing the complex IGA simulation process. A long bidirectional short-term memory (BLSTM) recurrent neural network is trained using the load and gradient index as inputs and the displacement responses as outputs. The nonlinear relationship between the outputs and the inputs… More >

  • Open Access

    ARTICLE

    STUDY OF INTERNAL FLOW CHARACTERISTICS OF INJECTOR FUELLED WITH VARIOUS BLENDS OF DIETHYL ETHER AND DIESEL USING CFD

    Vijayakumar Thulasi*, Thundil Karuppa Raj Rajagopal

    Frontiers in Heat and Mass Transfer, Vol.4, No.2, pp. 1-5, 2013, DOI:10.5098/hmt.v4.2.3007

    Abstract Researchers across the world are exploring the potential of using diethyl ether as an alternate fuel to meet the stringent emission norms due to the high oxygen content in the fuel. The spray characteristics of any injected fuel are highly influenced by its physical properties. Due to high injection pressure in CI engines the fuel tends to cavitate inside the nozzle greatly. The change in fuel properties will affect the cavitating behavior of the fuel. In this paper computational technique is used to study and compare the internal flow characteristics of a fuel injector for different blends of diethyl ether… More >

  • Open Access

    REVIEW

    Flow Regimes in Bubble Columns with and without Internals: A Review

    Ayat N. Mahmood1, Amer A. Abdulrahman1, Laith S. Sabri1,*, Abbas J. Sultan1, Hasan Shakir Majdi2, Muthanna H. Al-Dahhan3

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.2, pp. 239-256, 2024, DOI:10.32604/fdmp.2023.028015

    Abstract Hydrodynamics characterization in terms of flow regime behavior is a crucial task to enhance the design of bubble column reactors and scaling up related methodologies. This review presents recent studies on the typical flow regimes established in bubble columns. Some effort is also provided to introduce relevant definitions pertaining to this field, namely, that of “void fraction” and related (local, chordal, cross-sectional and volumetric) variants. Experimental studies involving different parameters that affect design and operating conditions are also discussed in detail. In the second part of the review, the attention is shifted to cases with internals of various types (perforated… More >

  • Open Access

    ARTICLE

    MHD CONVECTIVE BOUNDARY LAYER FLOW TOWARDS A VERTICAL SURFACE IN A POROUS MEDIUM WITH RADIATION, CHEMICAL REACTION AND INTERNAL HEAT GENERATION

    Emmanuel Maurice Arthur*, Timothy Ayando, Yakubu Ibrahim Seini

    Frontiers in Heat and Mass Transfer, Vol.6, pp. 1-10, 2015, DOI:10.5098/hmt.6.21

    Abstract The combined effects of chemical reaction and viscous dissipation on hydromagnetic mixed convective flow towards a vertical plate embedded in a highly porous medium with radiation and internal heat generation has been examined. The governing boundary layer equations have been transformed to a two-point boundary value problem using a local similarity approach and solved numerically using the Newton Raphson shooting method alongside the Fourth-order Runge - Kutta algorithm. The effects of various embedded parameters on fluid velocity, temperature and concentration have been presented graphically whilst the skin friction coefficient and the rates of heat and mass transfers have been tabulated… More >

  • Open Access

    ARTICLE

    Analysis of Profile and Unsteady Flow Performance of Variable Base Circle Radius Scroll Expander

    Junying Wei*, Gang Li, Chenrui Zhang, Wenwen Chang, Jidai Wang

    Frontiers in Heat and Mass Transfer, Vol.21, pp. 199-214, 2023, DOI:10.32604/fhmt.2023.041793

    Abstract To study the complex internal flow field variation and output characteristics of a variable base radius scroll expander, this paper uses dynamic mesh techniques and computational fluid dynamics (CFD) methods to perform transient numerical simulations of a variable base radius scroll expander. Analysis of the flow field in the working cavity of a variable base radius scroll expander at different spindle angles and the effect of different profiles, speeds and pressures on the output characteristics of the scroll expander. The results of the study show that due to the periodic blocking of the inlet by the orbiting scroll, the fluid… More >

  • Open Access

    ARTICLE

    Numerical Simulation of Heat Transfer of High-Temperature Slag Flow Inside the Blast Furnace Slag Trench

    Guangyan Fan, Fuyong Su*, Cunwang Li, Bin Li

    Frontiers in Heat and Mass Transfer, Vol.21, pp. 281-292, 2023, DOI:10.32604/fhmt.2023.043221

    Abstract To investigate the flow and heat transfer process of blast furnace slag through the slag trench after the slag is discharged, a three-dimensional physical model is established and simulated according to the actual size of the slag trench and the physical properties of the high-temperature slag. The temperature fied and flow field distribution of the high-temperature slag liquid inside the slag trench is obtained by numerical simulation under different working conditions, and the effects of operating conditions such as slag trench inclination, high-temperature slag inlet flow rate, and inlet temperature are investigated. The results show that the flow rate of… More >

  • Open Access

    ARTICLE

    Numerical Examination of Free Convection Flow of Casson Ternary Hybrid Nanofluid across Magnetized Stretching Sheet Impacted by Newtonian Heating

    Mohammed Z. Swalmeh1,*, Firas A. Alwawi2, A. A. Altawallbeh3, Wejdan Mesa’adeen4, Feras M. Al Faqih4, Ahmad M. Awajan4

    Frontiers in Heat and Mass Transfer, Vol.21, pp. 505-522, 2023, DOI:10.32604/fhmt.2023.044300

    Abstract In current study, the influence of magnetic field (MHD) on heat transfer of natural convection boundary layer flow in Casson ternary hybrid nanofluid past a stretching sheet is studied using numerical simulation. The Newtonian heating boundary conditions that depend on the temperature and velocity terms are taken into this investigation. The particular dimensional governing equations, for the studied problem, are converted to the system of partial differential equations utilizing adequate similarity transformation. Consequently, the system of equations is numerically solved using well-known Kellar box numerical techniques. The obtained numerical results are in excellent approval with previous literature results. The existence… More >

  • Open Access

    ARTICLE

    Diagnostic and classification value of immune-related lncRNAs in dilated cardiomyopathy

    CONGCHEN BAI1, QIHANG KONG2, HAO TANG2, SHUWEN ZHANG2, JUNTENG ZHOU3,*, XIAOJING LIU2,4,*

    BIOCELL, Vol.47, No.11, pp. 2517-2533, 2023, DOI:10.32604/biocell.2023.043864

    Abstract Background: Various physiological mechanisms are linked to dilated cardiomyopathy (DCM) development, including oxidative stress, immune irregularities, inflammation, fibrosis, and genetic changes. However, precise molecular drivers of DCM, especially regarding abnormal immune responses, remain unclear. This study investigates immune-related long non-coding RNAs (lncRNAs) in DCM’s diagnostic and therapeutic potential. Methods: GSE141910, GSE135055, and GSE165303 datasets were acquired from the GEO database. LASSO, SVM-RFE, and random forest algorithms identified DCM-associated immune-related lncRNAs. Diagnostic capabilities were assessed by Nomogram and receiver operating characteristic (ROC) curves. Multivariate linear regression explored lncRNA correlations with ejection fraction. Single-sample gene set enrichment analysis (ssGSEA) gauged immune cell… More > Graphic Abstract

    Diagnostic and classification value of immune-related lncRNAs in dilated cardiomyopathy

  • Open Access

    ARTICLE

    Analysis of differentially expressed genes in Verruca vulgaris vs. adjacent normal skin by RNA-sequencing

    QINGQING GUO1,2, JIAYUE QI1,2, XIAOQIANG LIANG2, ZIGANG ZHAO2, JIA BAI2, FANG XIE2,#,*, CHENGXIN LI1,2,#,*

    BIOCELL, Vol.47, No.11, pp. 2435-2443, 2023, DOI:10.32604/biocell.2023.043126

    Abstract Introduction: Verruca vulgaris is one of the most common low-risk HPV infections and is characterized by excessive proliferation of keratinocytes. Currently, very little genetic information is available regarding verruca vulgaris in the Chinese population. This study aimed to obtain comprehensive transcript information of verruca vulgaris by RNA sequencing. Methods: High-throughput sequencing was performed on three fresh verruca vulgaris samples and adjacent normal skin on the Illumina sequencing platform. The transcriptomes were analyzed using bioinformatics and the differentially expressed genes (DEGs) were verified by immunohistochemistry. Verruca vulgaris exhibited a unique molecular signature. Results: In total, 1,643 DEGs were identified in verruca… More >

  • Open Access

    REVIEW

    New perspectives on biology, disease progression, and therapy response of head and neck cancer gained from single cell RNA sequencing and spatial transcriptomics

    GERWIN HELLER1,*, THORSTEN FUEREDER1, ALEXANDER MICHAEL GRANDITS1, ROTRAUD WIESER1,2,*

    Oncology Research, Vol.32, No.1, pp. 1-17, 2024, DOI:10.32604/or.2023.044774

    Abstract Head and neck squamous cell carcinoma (HNSCC) is one of the most frequent cancers worldwide. The main risk factors are consumption of tobacco products and alcohol, as well as infection with human papilloma virus. Approved therapeutic options comprise surgery, radiation, chemotherapy, targeted therapy through epidermal growth factor receptor inhibition, and immunotherapy, but outcome has remained unsatisfactory due to recurrence rates of ~50% and the frequent occurrence of second primaries. The availability of the human genome sequence at the beginning of the millennium heralded the omics era, in which rapid technological progress has advanced our knowledge of the molecular biology of… More >

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