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  • Open Access

    ARTICLE

    Turbulent Kinetic Energy of Flow during Inhale and Exhale to Characterize the Severity of Obstructive Sleep Apnea Patient

    W. M. Faizal1,*, C. Y. Khor1, Muhammad Nooramin Che Yaakob1, N. N. N. Ghazali2, M. Z. Zainon2, Norliza Binti Ibrahim3, Roziana Mohd Razi4

    CMES-Computer Modeling in Engineering & Sciences, Vol.136, No.1, pp. 43-61, 2023, DOI:10.32604/cmes.2023.022716

    Abstract This paper aims to investigate and present the numerical investigation of airflow characteristics using Turbulent Kinetic Energy (TKE) to characterize the upper airway with obstructive sleep apnea (OSA) under inhale and exhale breathing conditions. The importance of TKE under both breathing conditions is that it show an accurate method in expressing the severity of flow in sleep disorder. Computational fluid dynamics simulate the upper airway’s airflow via steady-state Reynolds-averaged Navier-Stokes (RANS) with k–ω shear stress transport (SST) turbulence model. The three-dimensional (3D) airway model is created based on the CT scan images of an actual patient, meshed with 1.29 million… More > Graphic Abstract

    Turbulent Kinetic Energy of Flow during Inhale and Exhale to Characterize the Severity of Obstructive Sleep Apnea Patient

  • Open Access

    ARTICLE

    Sensor-Based Gait Analysis for Parkinson’s Disease Prediction

    Sathya Bama B*, Bevish Jinila Y

    Intelligent Automation & Soft Computing, Vol.36, No.2, pp. 2085-2097, 2023, DOI:10.32604/iasc.2023.028481

    Abstract Parkinson’s disease is identified as one of the key neurodegenerative disorders occurring due to the damages present in the central nervous system. The cause of such brain damage seems to be fully explained in many research studies, but the understanding of its functionality remains to be impractical. Specifically, the development of a quantitative disease prediction model has evolved in recent decades. Moreover, accelerometer sensor-based gait analysis is accepted as an important tool for recognizing the walking behavior of the patients during the early prediction and diagnosis of Parkinson’s disease. This type of minimal infrastructure equipment helps in analyzing the Parkinson’s… More >

  • Open Access

    ARTICLE

    Magnetic mitohormesis: A non-invasive therapy for inflammatory disorders?

    ALFREDO FRANCO-OBREGÓN*

    BIOCELL, Vol.47, No.2, pp. 239-244, 2023, DOI:10.32604/biocell.2023.025357

    Abstract An organism’s survival depends on its ability to adapt to stress. Mitochondria are the cellular integrators of environmental stressors that ultimately translate their responses at the organismal level, and are thus central to the process whereby organisms adapt to their respective environments. Mitochondria produce molecular energy via oxidative phosphorylation that then allows cells to biosynthetically respond and adapt to changes in their environment. Reactive oxygen species (ROS) are by-products of oxidative phosphorylation that can be either beneficial or damaging, depending on the context; ROS are hence both the conveyors of environmental stress as well as cellular “adaptogens”. Mitohormesis refers to… More >

  • Open Access

    ARTICLE

    The Contribution of BMI, Body Image Inflexibility, and Generalized Anxiety to Symptoms of Eating Disorders and Exercise Dependence in Exercisers

    Liye Zou1,2, Peiying Yang1, Fabian Herold3, Weina Liu1, Attila Szabo4, Alyx Taylor5, Jing Sun6, Liu Ji1,*

    International Journal of Mental Health Promotion, Vol.24, No.6, pp. 811-823, 2022, DOI:10.32604/ijmhp.2022.024862

    Abstract 1) Background: The common factors which potentially contribute to the development of eating disorders and exercise dependence during early adulthood are still relatively unclear. The present study aimed to examine the role of BMI, body image inflexibility, and generalized anxiety in these two behavioral problems in a sample of college students. 2) Methods: In total, 878 habitual exercisers (58.1% male with BMI = 22.12 ± 2.39; 41.9% female with BMI = 20.55 ± 2.21) with age of 20.09 ± 1.76 years participated in this study. The main outcomes of interest are exercise dependence symptoms, eating disorders symptoms, body image inflexibility, and symptoms of generalized anxiety (as measured by Exercise Dependence… More >

  • Open Access

    ARTICLE

    Mental Health Disorders of the Indonesian People in the Early Stages of the COVID-19 Pandemic: Who is Vulnerable to Experiencing it?

    Rofingatul Mubasyiroh1,*, Indri Yunita Suryaputri1, Sri Idaiani2, Lely Indrawati1, Tri Wurisastuti1, Siti Isfandari1, Nikson Sitorus1, Enung Nurhotimah3, Felly Philipus Senewe1

    International Journal of Mental Health Promotion, Vol.24, No.5, pp. 725-737, 2022, DOI:10.32604/ijmhp.2022.021452

    Abstract The extraordinary situation related to COVID-19 makes people worry about their health, family health, work, finances, and other daily activities. This condition can lead to social unrest, which has consequences for mental health problems. This study aims to determine the mental health consequences at the beginning of the COVID-19 pandemic in Indonesia. This is a cross-sectional study involving a target population aged 18 years and over who had access to electronic communication devices. An online questionnaire was randomly distributed and snowballed throughout 34 provinces in Indonesia. The study was conducted from 2 to 4 May 2020. Non-parametric and multivariate linear… More >

  • Open Access

    ARTICLE

    Application Progress of Aromatherapy in Perioperative Patients

    Yuezi Liao1,2,*, Xing Liu1,2, Mengqin Zhang1,2, Hao Hua3

    Journal of Intelligent Medicine and Healthcare, Vol.1, No.1, pp. 1-10, 2022, DOI:10.32604/jimh.2022.029848

    Abstract Aromatherapy is a sort of natural therapy for body maintenance using essential oils and vegetable oils extracted from natural plants. It belongs to the category of homeopathy. Aromatherapy combines the dual functions of art and treatment, comprehensively considers the needs of human physiology and psychology, and is widely used in the field of medical care. Aromatherapy is one of the complementary and alternative treatments extensively studied at home and abroad. It has a relieving effect on postoperative pain, sleep disturbance, nausea, vomiting and preoperative anxiety, and is an important intervention in perioperative care. A large number of research data show… More >

  • Open Access

    ARTICLE

    Nonprecsion (Standard) Psychosocial Interventions for the Treatment of Mental Disorders

    Alan E. Kazdin*

    International Journal of Mental Health Promotion, Vol.24, No.4, pp. 457-473, 2022, DOI:10.32604/ijmhp.2022.022522

    Abstract Advances in precision treatment promise to greatly improve the extent to which therapies for mental disorders are better matched to patient characteristics. At the same, we need to ensure that more readily disseminable and available nonprecison treatments are further developed as well. These treatments refer to standardized interventions that do not have to be individualized and are more readily available. Impetus for this call stems from the treatment gap, namely, the huge difference in the proportion of individuals who are in need of mental health services and who actually receive any form of treatment. The prevalence rates for mental disorders… More >

  • Open Access

    REVIEW IN FRENCH

    Hairy Cell Leukemia and HCL-Like Disorders: Diagnosis and Treatment
    Leucémie à Tricholeucocytes et Autres Proliférations à Cellules Chevelues: Diagnostic et Traitement

    Elsa Maitre, Xavier Troussard*

    Oncologie, Vol.24, No.1, pp. 3-24, 2022, DOI:10.32604/oncologie.2022.021490

    Abstract Hairy cell leukemia (LT) accounts for 2% of all leukemias. The diagnosis is based on the presence in the blood and/ or the marrow of hairy cells expressing CD103, CD123, CD11c and CD25. The BRAFV600E mutation, a molecular marker of the disease, is present in more than 80% of cases. LT should be distinguished from other chronic B-cell lymphoproliferative disorders, including the variant form of hairy cell leukemia (HCL-V) and diffuse splenic red pulp lymphoma (DSRPL). Progress has recently been made in the management of patients. The purine analogues (PNAs) in monotherapy, deoxycoformycin (DCF) or 2-chloro-deoxyadenosine (CDA), remain the first-line… More >

  • Open Access

    ARTICLE

    Mental Health Literacy of University Students in Vietnam and Cambodia

    Anja Dessauvagie1, Hoang-Minh Dang2, Tuyet Truong3, Thu Nguyen4, Bich Hong Nguyen5, Huong Cao6, Socheata Kim7, Gunter Groen1,*

    International Journal of Mental Health Promotion, Vol.24, No.3, pp. 439-456, 2022, DOI:10.32604/ijmhp.2022.018030

    Abstract Mental health literacy (MHL) refers to knowledge and attitudes that shape the recognition, management, and prevention of mental disorders. While the topic has been exhaustively researched in Western countries, research from Southeast Asia still is limited. Previous studies in this field showed a moderate recognition of mental disorders, a high prevalence of stigmatizing attitudes and a low willingness to seek professional help among Southeastern-Asian populations. This study explored the level of MHL among university students from different parts of Vietnam and Cambodia. Correlations with influencing factors (gender, age, study year, educational attainment of the parents, urban/rural origin, ethnicity, personal experiences… More >

  • Open Access

    VIEWPOINT

    MSCs derived extracellular vesicles as a therapeutic paragon for neurodegenerative disorders: A viewpoint

    YASHVI SHARMA1, SHARDA RAY2, SUJATA MOHANTY1,*

    BIOCELL, Vol.46, No.6, pp. 1435-1438, 2022, DOI:10.32604/biocell.2022.018612

    Abstract Neurodegenerative disorders are a vicious woe to the public health and wellness. Uncertainty in their underlying causes, lack of effective biomarkers for their early detection, existence of only supportive therapy, and their ever rising incidence creates an unmatched need for targeted therapies. Mesenchymal Stem Cells (MSCs) have found to be promising candidates for regenerative and remedial therapy in neurodegenerative disorders, however several biological risks and practical issues impede in their translational utility. Deriving from MSCs are certain Extracellular Vesicles (EVs), which aid in the paracrine action of MSCs and have lately gained the scientific interest for their implacability in diverse… More >

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