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  • Open Access

    REVIEW

    Review on microbial metabolomics of probiotics and pathogens: Methodologies and applications

    XIN MENG*, XUE LI, LIANRONG YANG, RUI YIN, LEHUI QI, QI GUO

    BIOCELL, Vol.47, No.1, pp. 91-107, 2023, DOI:10.32604/biocell.2023.024310

    Abstract In recent years, microbial metabolomics, a new field that has attracted wide attention, provides a map of metabolic pathways and clarifies the interaction mechanism between microorganisms and hosts. Many microorganisms are found in the human intestine, oral cavity, vagina, etc. Probiotics could maintain the good health of the host, while pathogens and an imbalance of bacterial flora lead to a series of diseases of the body and mind. Metabolomics is a science for qualitative and quantitative analysis of all metabolites in an organism or biological system, which could provide key information to understand the related metabolic pathways and associated changes.… More >

  • Open Access

    ARTICLE

    In Vitro Anti-Bacterial and Anti-Fungal Activities of Extracts from Different Parts of 7 Zingiberaceae Plants

    Lixian Wu1,#, Yongquan Li1,#, Qiaoguang Li2, Jingxuan Li1, Qinghua Lao1, Yucheng Zhong1, Hui Zhang1,*, Xiu Hu1,*

    Journal of Renewable Materials, Vol.11, No.2, pp. 975-989, 2023, DOI:10.32604/jrm.2022.023547

    Abstract This study aimed to explore the anti-bacterial and anti-fungal activities of extracts from different parts of plants in the Zingiberaceae family. The inhibitory rate, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) of leaf and stem, and root and rhizome extracts from Alpinia katsumadai Hayata, Alpinia oxyphylla Miq × Alpinia henryi K. Schumann, Alpinia oblongifolia Hayata, Alpinia nigra (Gaertn.) Burtt, Amomum villosum Lour, Alpinia zerumbet (Pers.) Burtt. et Smith and Alpinia oxyphylla Miq were determined using the fungus cake method and double dilution method. The seven Zingiberaceae plants exhibited characteristic antibacterial activities against pathogenic bacteria and fungi. At a… More >

  • Open Access

    ARTICLE

    Characterization and Pathogenicity of Pseudopestalotiopsis vietnamensis Causing Gray Blight of Wuyi Rock Tea (Camellia sinensis) in China and Specific Mechanisms of Disease Infection

    Guangheng Wu1,#,*, Lu Rui2,3,#, Xiang Lu4, Libo Han2, Gan Lv1, Xianyu Fu5, Jinxian Liu5, Nong Zhou3, Chuanhai Zhang1

    Phyton-International Journal of Experimental Botany, Vol.92, No.1, pp. 131-147, 2023, DOI:10.32604/phyton.2022.021919

    Abstract Gray blight disease (GBD) causes significant losses in tea production in China. Although genes and biological processes involved in resistance to fungal disease in tea plants have been identified, specific mechanisms of the GBD infection process remain unknown. In this study, morphological and multi-gene (TEF-TUB-ITS) phylogenetic characteristics were used to identify isolate CLBB1 of Pseudopestalotiopsis vietnamensis. Pathogenicity tests confirmed that isolate CLBB1 from tea leaves caused GBD in the susceptible tea cultivar Wuyi Rock (Camellia sinensis var. sinensis cv. Shuixian). Spores began to germinate 24 h after infection (hai), and after 48 h, elongated fungal hyphae formed from a single conidium. Transcriptome… More >

  • Open Access

    ARTICLE

    Detection of Diabetic Retinopathy from Retinal Images Using DenseNet Models

    R. Nandakumar1, P. Saranya2,*, Vijayakumar Ponnusamy3, Subhashree Hazra2, Antara Gupta2

    Computer Systems Science and Engineering, Vol.45, No.1, pp. 279-292, 2023, DOI:10.32604/csse.2023.028703

    Abstract A prevalent diabetic complication is Diabetic Retinopathy (DR), which can damage the retina’s veins, leading to a severe loss of vision. If treated in the early stage, it can help to prevent vision loss. But since its diagnosis takes time and there is a shortage of ophthalmologists, patients suffer vision loss even before diagnosis. Hence, early detection of DR is the necessity of the time. The primary purpose of the work is to apply the data fusion/feature fusion technique, which combines more than one relevant feature to predict diabetic retinopathy at an early stage with greater accuracy. Mechanized procedures for… More >

  • Open Access

    ARTICLE

    Synthesis, Characterization and Remedial Action of Biogenic Silver Nanoparticles and Chitosan-Silver Nanoparticles against Bacterial Pathogens

    Piyush Kumar Gupta1, D. Karthik Kumar2, M. Thaveena3, Soumya Pandit1, Somya Sinha4, R. Ranjithkumar2,* , Walaa F. Alsanie5, Vijay Kumar Thakur6,7,8,*

    Journal of Renewable Materials, Vol.10, No.12, pp. 3093-3105, 2022, DOI:10.32604/jrm.2022.019335

    Abstract Custard apple is a dry land fruit. Its leaves exhibit different pharmacological activities. In the present study, both silver (Ag) nanoparticles and chitosan-coated Ag (Chi-Ag) nanoparticles were fabricated using the aqueous leaf extract of the custard apple plant. During preliminary phytochemical analysis, various types of phytocompounds were found in the aqueous leaf extract of the same plant. Next, both nanoparticles were physiochemically characterized. FTIR analysis exhibited the fingerprint vibrational peaks of active bioactive compounds in plant extract, Ag nanoparticles, and Chi-Ag nanoparticles. UV/Visible spectral analysis revealed the highest absorbance peak at 419 nm, indicating the presence of Ag nanoparticles. XRD… More > Graphic Abstract

    Synthesis, Characterization and Remedial Action of Biogenic Silver Nanoparticles and Chitosan-Silver Nanoparticles against Bacterial Pathogens

  • Open Access

    REVIEW

    Distribution, Etiology, Molecular Genetics and Management Perspectives of Northern Corn Leaf Blight of Maize (Zea mays L.)

    M. Ashraf Ahangar1, Shabir Hussain Wani1,*, Zahoor A. Dar2, Jan Roohi1, Fayaz Mohiddin1, Monika Bansal3, Mukesh Choudhary4, Sumit K. Aggarwal4, S. A. Waza1, Khursheed Ahmad Dar5, Ayman El Sabagh6,7, Celaleddin Barutcular8, Omer Konuşkan9, Mohammad Anwar Hossain10,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.10, pp. 2111-2133, 2022, DOI:10.32604/phyton.2022.020721

    Abstract Maize is cultivated extensively throughout the world and has the highest production among cereals. However, Northern corn leaf blight (NCLB) disease caused by Exherohilum turcicum, is the most devastating limiting factor of maize production. The disease causes immense losses to corn yield if it develops prior or during the tasseling and silking stages of crop development. It has a worldwide distribution and its development is favoured by cool to moderate temperatures with high relative humidity. The prevalence of the disease has increased in recent years and new races of the pathogen have been reported worldwide. The fungus E. turcicum is… More >

  • Open Access

    ARTICLE

    Identification of a new Hazelnut disease in Liaoning Province: Hazelnut husk brown rot

    JUN SUN1,*, MING XIE1, JIACHEN HAO1, NAN MAO1, LIJING CHEN2,*, YUANYUAN QIN3

    BIOCELL, Vol.46, No.9, pp. 2145-2149, 2022, DOI:10.32604/biocell.2022.020500

    Abstract Hazelnut husk brown rot has been identified as a new disease in Liaoning Province in recent years. The objective of this study as to identify the pathogen. [Method] In this study, a standard sample of hazelnut husk brown rot was collected from Songmudao Base in Dalian City, Liaoning Province. The pathogen was identified by the studies of the morphology, pathogenicity, and analyses of ITS and LSU sequences. The pathogen was isolated and purified, which was confirmed by Koch’s postulates. The symptoms after inoculation were the same as those collected directly from a diseased tree, which showed that it was the… More >

  • Open Access

    REVIEW

    Antagonistic Potential of Bacterial Species against Fungal Plant Pathogens (FPP) and Their Role in Plant Growth Promotion (PGP): A Review

    Amjad Ali1, Yasir Iftikhar2,*, Mustansar Mubeen2, Haider Ali3, Muhammad Ahmad Zeshan2, Zohaib Asad4, Muhammad Zafar-ul-Hye5, Malik Abdul Rehman6, Mazhar Abbas7, Muhammad Rafique8, Muhammad Usman Ghani9

    Phyton-International Journal of Experimental Botany, Vol.91, No.9, pp. 1859-1877, 2022, DOI:10.32604/phyton.2022.021734

    Abstract

    Since the 19th century to date, the fungal pathogens have been involved in causing devastating diseases in plants. All types of fungal pathogens have been observed in important agricultural crops that lead to significant pre and postharvest losses. The application of synthetic fungicide against the fungal plant pathogens (FPP) is a traditional management practice but at the same time these fungicides kill other beneficial microbes, insects, animal, and humans and are harmful to environment. The antagonistic microorganism such as bacteria are being used as an alternate strategy to control the FPP. These antagonistic species are cost-effective and eco-friendly in nature.… More > Graphic Abstract

    Antagonistic Potential of Bacterial Species against Fungal Plant Pathogens (FPP) and Their Role in Plant Growth Promotion (PGP): A Review

  • Open Access

    ARTICLE

    Astaxanthin delayed the pathogenesis of diabetic nephropathy in type 1 diabetic rats

    LIANHUAN MA1, SHOUPENG LIU2, XIAOWEN ZHEN1, WEIWEI QIAO1, LINA MA1, XIAOMIN ZHANG3,*

    BIOCELL, Vol.46, No.8, pp. 1911-1916, 2022, DOI:10.32604/biocell.2022.019277

    Abstract This study was designed to investigate the protective effects of Astaxanthin (AST) in rats with diabetes mellitus (DM) induced by streptozotocin. SD rats were divided into control group (n = 5, only received normal saline), DM group (n = 8) and AST + DM group (n = 8; AST: 50 mg/kg/day). DM rats were induced by intraperitoneal injection of streptozocin (STZ, 65 mg/kg). Blood glucose level and body weight were determined at weeks 0, 2, 4, 6 and 8, respectively. At week 8, kidney function was determined, together with expression of P53 and dynamin-related protein-1 (Drp1) by Western blot analysis… More >

  • Open Access

    ARTICLE

    A Novel COVID-19 Prediction Model with Optimal Control Rates

    Ashraf Ahmed1, Yousef AbuHour2,*, Ammar El-Hassan1

    Intelligent Automation & Soft Computing, Vol.32, No.2, pp. 979-990, 2022, DOI:10.32604/iasc.2022.020726

    Abstract The Corona (COVID-19) epidemic has triggered interest in many fields of technology, medicine, science, and politics. Most of the mathematical research in this area focused on analyzing the dynamics of the spread of the virus. In this article, after a review of some current methodologies, a non-linear system of differential equations is developed to model the spread of COVID-19. In order to consider a wide spectrum of scenarios, we propose a susceptible-exposed-infected-quarantined-recovered (SEIQRS)-model which was analyzed to determine threshold conditions for its stability, and the number of infected cases that is an infected person will transmit on a virus to,… More >

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