ILGIZ GAREEV¹, OZAL BEYLERLI¹, CHUNLEI WANG^2,3, ANDREI SOKHATSKII^2,3, YANCHAO LIANG^2,3, HUAN XIANG^2,3, CHUNYANG LIU^2,3, XUN XU^2,3, YANG GUANG^2,3

BIOCELL, Vol.46, No.1, pp. 27-35, 2022, DOI:10.32604/biocell.2022.016288

Abstract Brain arteriovenous malformations (AVMs) are abnormal vessels that are prone to rupture, causing life-threatening intracerebral hemorrhage (ICH). Understanding the molecular basis of pathogenesis, timely diagnosis, and treatment of brain AVMs are some of the urgent problems in neurosurgery. MicroRNAs (miRNAs) are small endogenous RNAs that regulate gene-expression posttranscriptionally. MiRNAs are involved in almost all biological processes, including cell proliferation, apoptosis, and cell differentiation. Recent studies have shown that miRNAs can be involved in brain AVMs formation and rupture. There are also extracellular forms of miRNAs. Circulating miRNAs have been detected in the blood circulation and other body fluids. Owing to… More >

JELAN MOFEED^1,2, MOHAMED DEYAB³, ABDELNASER MOHAMED³, MAHMOUD MOUSTAFA^4,5, SALLY NEGM^6,7, EMAD EL-BILAWY¹

BIOCELL, Vol.46, No.1, pp. 247-261, 2022, DOI:10.32604/biocell.2022.015966

Abstract

Microbial infections cause complicated health influences along with bad economic impacts. In the present investigation, three dominant seaweeds namely, Amphiroa anceps, Corallina officinalis and Sargassum filipendula were collected from different Egyptian sites at the Red Sea and Mediterranean Sea during autumn 2019. Organic extracts of the three algae were screened for their antibacterial activity against three pathogenic bacteria Salmonella typhiimurium, Staphylococcus aureus and Escherichia coli, in addition to in vitro antiviral activity against Rotavirus (RV), and Coxsackie virus B3 (CVB3) that cause severe diseases in human. Organic extract of A. anceps, C. officinalis and S. filipendula inhibit E. coli cells… More >

Muyu Qi^1,#, Xiaoping Lan^2,#, Jia Li¹, Junwen Ge¹, Li Shen^1,*, Rufang Zhang^1,*

Congenital Heart Disease, Vol.16, No.5, pp. 487-498, 2021, DOI:10.32604/CHD.2021.015887

Abstract Objective: Pulmonary atresia (PA) is a rare type of complex cyanotic congenital heart defect characterized primarily by an undeveloped pulmonary valve or pulmonary artery. Therefore, defining a disease-causing gene mutation in a pulmonary atresia family is a possible method of genetic counseling, future prenatal diagnosis, and therapeutic approaches for pulmonary atresia. Methods: Blood samples were collected from six PA family members, and genomic DNA was extracted using the QIAamp DNA Blood Mini Kit. Gene detection was performed using a second-generation sequencing gene panel. Results: Genetic testing results indicated that a heterozygous mutation originating from maternal inheritance was detected in the… More >

Luis Alfonso Aguilar Pérez^1,*, Daniel Nieto Ángel^1,*, Moisés Roberto Vallejo Pérez², Daniel Leobardo Ochoa Martínez¹, David Espinosa Victoria³, Andrés Rebolledo Martinez⁴, Abel Rebouças São José⁵

Phyton-International Journal of Experimental Botany, Vol.90, No.4, pp. 1205-1216, 2021, DOI:10.32604/phyton.2021.015109

Abstract The development and implementation of sustainable and environmentally friendly agricultural practices are indispensable as alternatives to pesticide use and to keep populations of soil-borne plant pathogens at levels that do not affect crop productivity. The present research evaluates the incidence of soil-borne phytopathogens on the pineapple variety MD-2, which was subjected to different treatments: Incorporation of Crotalaria juncea into the soil (organic amendment), application of dolomitic lime to soil (inorganic amendment), and the use of plastic mulch covering the soil. During the crop cycle (15 months), the following variables were evaluated: plant height (cm), fruit weight (kg·plant⁻¹ ), crop yield… More >

Elio Caruso^*, Silvia Farruggio, Salvatore Agati, Corrado Di Mambro

Congenital Heart Disease, Vol.16, No.4, pp. 309-331, 2021, DOI:10.32604/CHD.2021.015470

Abstract Fetal arrhythmias reach up around 10% of the total third-level perinatal cardiology references. Sustained bradycardia is defined as a baseline fetal heart rate (FHR) of less than 110 bpm sustained for at least 10 min. The overall incidence of malignant fetal bradyarrhythmias, such as complete atrioventricular block (AVB) and channellopathies, is relatively rare, 1:5000 pregnancies, but represents a serious emergency for the gynecologist, neonatologists, and pediatric cardiologists. Fetal complete AVB is strongly associated with maternal connective tissue disease, but it can be also associated with congenital heart disease and usually with a poorer prognosis with high risk of fetal hydrops… More >

Roberto Arredondo-Valdés¹, Francisco D. Hernández-Castillo², Mario Rocandio-Rodríguez¹, Julia C. Anguiano-Cabello³, Madai Rosas-Mejía¹, Venancio Vanoye-Eligio¹, Salvador Ordaz-Silva⁴, Imelda V. López-Sánchez⁴, Laura D. Carrazco-Peña⁴, Julio C. Chacón-Hernández^1,*

Phyton-International Journal of Experimental Botany, Vol.90, No.3, pp. 895-906, 2021, DOI:10.32604/phyton.2021.014301

Abstract The tomato (Solanum lycopersicum L.) is one of the world’s most important vegetable crops. Still, phytopathogenic bacteria affect the yield and quality of tomato cultivation, like Agrobacterium tumefeciens (At), Clavibacter michiganensis subsp. michiganensis (Cmm), Pseudomonas syringae pv. tomato (Pst), Ralstonia solanacearum (Rs), and Xanthomonas axonopodis (Xa). Synthetic chemical products are used mostly on disease plant control, but overuse generates resistance to bacterial control. This study aimed to evaluate the in vitro antibacterial activity of the ethanolic extract of Moringa oleifera Lam. leaves against At, Cmm, Pst, Rs, and Xa, as well as information about this plant species’ chemical composition. Antibacterial… More >

Mercedes Georgina Ramírez-Aragón¹, Victoria Jared Borroel-García¹, Ramón Valenzuela-Soto¹, Ricardo David Valdez-Cepeda², Francisco Javier Wong-Corral³, José Luis García-Hernández^4,*

Phyton-International Journal of Experimental Botany, Vol.90, No.2, pp. 533-541, 2021, DOI:10.32604/phyton.2021.013166

Abstract The extraction of bioactive compounds has become one of the most interesting areas of modern chemistry. For therapeutic reasons, it´s important to obtain antimicrobial agents from natural origin. The objective of the present study was to determine the inhibitory effect of ethanolic extract of basil (Ocimum basilicum L. var. Red Rubin) subjected to different concentrations of potassium (K⁺) on the activity of three bacterial strains that are pathogens in humans. Susceptibility was evaluated by inhibition surface and these results were compared to two antibiotics: Gentamicin (GE) and Ciprofloxacin (CPF) for their efficacy against each bacterial strain. Analyzed variables presented significant… More >

EMILIA MANOLE^1,2,#, LAURA DUMITRESCU^2,3,#, CRISTINA NICULIȚE^1,3, BOGDAN OVIDIU POPESCU^1,2,3, LAURA CRISTINA CEAFALAN^1,3,*

BIOCELL, Vol.45, No.1, pp. 1-16, 2021, DOI:10.32604/biocell.2021.013452

Abstract An increasing number of studies provide evidence for the existence of a microbiota-gut-brain axis and its potential involvement in the development of sporadic Parkinson’s disease and other neurodegenerative conditions. The neuropathologic hallmark of Parkinson’s disease is the presence of brain intraneuronal aggregates of misfolded alpha-synuclein, known as Lewy bodies. Some gut microbiota products may trigger alpha-synuclein conformational changes in the neurons of the enteric nervous system, which can then spread to the brain in a prion-like fashion through the vagus nerve. Others may interfere with neuroinflammatory pathways and susceptibility to neurodegeneration. In this review, we assess the potential role of… More >

VIVEK KUMAR, VISHNU AGARWAL^*

BIOCELL, Vol.44, No.4, pp. 461-467, 2020, DOI:10.32604/biocell.2020.011090

Abstract The world is facing a new healthcare crisis with the rise and spread of novel coronavirus since December 2019. Also known as Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2), the disease associated with SARSCoV-2 is even called COVID-19. The infection is said to have originated from the bat community and transmitted to humans through an intermediate host (yet unknown) in Wuhan, in the Hubei region of China. COVID-19 is having a pulverizing impact on the scientific community. As of August 13, 2020, the number of confirmed cases had reached up to 20,439,814 and the death toll to 744,385, affecting more… More >

Sunil Kumar Sharma¹, Shivam Bhardwaj^2,*, Rashmi Bhardwaj³, Majed Alowaidi¹

CMC-Computers, Materials & Continua, Vol.66, No.1, pp. 805-825, 2021, DOI:10.32604/cmc.2020.011937

Abstract This article discusses short–term forecasting of the novel Corona Virus (COVID-19) data for infected and recovered cases using the ARIMA method for Saudi Arabia. The COVID-19 data was obtained from the Worldometer and MOH (Ministry of Health, Saudi Arabia). The data was analyzed for the period from March 2, 2020 (the first case reported) to June 15, 2020. Using ARIMA (2, 1, 0), we obtained the short forecast up to July 02, 2020. Several statistical parameters were tested for the goodness of fit to evaluate the forecasting methods. The results show that ARIMA (2, 1, 0) gave a better forecast… More >