Kun Yang^1,2,3, Shilong Chang¹, Yucheng Wang¹, Minghui Wang¹, Jiahui Yang¹, Shuang Liu^1,2,3, Kun Liu^1,2,3, Linyan Xue^1,2,3,*

CMC-Computers, Materials & Continua, Vol.78, No.1, pp. 393-410, 2024, DOI:10.32604/cmc.2023.044994

Abstract Clear cell renal cell carcinoma (ccRCC) represents the most frequent form of renal cell carcinoma (RCC), and accurate International Society of Urological Pathology (ISUP) grading is crucial for prognosis and treatment selection. This study presents a new deep network called Multi-scale Fusion Network (MsfNet), which aims to enhance the automatic ISUP grade of ccRCC with digital histopathology pathology images. The MsfNet overcomes the limitations of traditional ResNet50 by multi-scale information fusion and dynamic allocation of channel quantity. The model was trained and tested using 90 Hematoxylin and Eosin (H&E) stained whole slide images (WSIs), which were all cropped into 320… More >

Manas Ranjan Prusty¹, Rishi Dinesh², Hariket Sukesh Kumar Sheth², Alapati Lakshmi Viswanath², Sandeep Kumar Satapathy^2,3,*

CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3077-3094, 2023, DOI:10.32604/cmc.2023.042718

Abstract This paper presents a novel computerized technique for the segmentation of nuclei in hematoxylin and eosin (H&E) stained histopathology images. The purpose of this study is to overcome the challenges faced in automated nuclei segmentation due to the diversity of nuclei structures that arise from differences in tissue types and staining protocols, as well as the segmentation of variable-sized and overlapping nuclei. To this extent, the approach proposed in this study uses an ensemble of the UNet architecture with various Convolutional Neural Networks (CNN) architectures as encoder backbones, along with stain normalization and test time augmentation, to improve segmentation accuracy.… More >

Arslan Akram^1,2, Javed Rashid^2,3,4, Fahima Hajjej⁵, Sobia Yaqoob^1,6, Muhammad Hamid⁷, Asma Irshad⁸, Nadeem Sarwar^9,*

CMC-Computers, Materials & Continua, Vol.77, No.1, pp. 1081-1101, 2023, DOI:10.32604/cmc.2023.041558

Abstract Around one in eight women will be diagnosed with breast cancer at some time. Improved patient outcomes necessitate both early detection and an accurate diagnosis. Histological images are routinely utilized in the process of diagnosing breast cancer. Methods proposed in recent research only focus on classifying breast cancer on specific magnification levels. No study has focused on using a combined dataset with multiple magnification levels to classify breast cancer. A strategy for detecting breast cancer is provided in the context of this investigation. Histopathology image texture data is used with the wavelet transform in this technique. The proposed method comprises… More >

Muhammad Junaid Umer¹, Muhammad Sharif¹, Majed Alhaisoni², Usman Tariq³, Ye Jin Kim⁴, Byoungchol Chang^5,*

Computer Systems Science and Engineering, Vol.45, No.2, pp. 1001-1016, 2023, DOI:10.32604/csse.2023.030463

Abstract Breast cancer (BC) is a most spreading and deadly cancerous malady which is mostly diagnosed in middle-aged women worldwide and effecting beyond a half-million people every year. The BC positive newly diagnosed cases in 2018 reached 2.1 million around the world with a death rate of 11.6% of total cases. Early diagnosis and detection of breast cancer disease with proper treatment may reduce the number of deaths. The gold standard for BC detection is biopsy analysis which needs an expert for correct diagnosis. Manual diagnosis of BC is a complex and challenging task. This work proposed a deep learning-based (DL)… More >

Ali G. Alkhathami^*

Intelligent Automation & Soft Computing, Vol.34, No.1, pp. 235-247, 2022, DOI:10.32604/iasc.2022.024952

Abstract Breast cancer is one of the main causes of death in women. When body tissues start behaves abnormally and the ratio of tissues growth becomes asymmetrical then this stage is called cancer. Invasive ductal carcinoma (IDC) is the early stage of breast cancer. The early detection and diagnosis of invasive ductal carcinoma is a significant step for the cure of IDC breast cancer. This paper presents a convolutional neural network (CNN) approach to detect and visualize the IDC tissues in breast on histological images dataset. The dataset consists of 90 thousand histopathological images containing two categories: Invasive Ductal Carcinoma positive… More >

Nishant Behar^*, Manish Shrivastava

CMES-Computer Modeling in Engineering & Sciences, Vol.130, No.2, pp. 823-839, 2022, DOI:10.32604/cmes.2022.017030

Abstract Breast cancer is considered an immense threat and one of the leading causes of mortality in females. It is curable only when detected at an early stage. A standard cancer diagnosis approach involves detection of cancer-related anomalies in tumour histopathology images. Detection depends on the accurate identification of the landmarks in the visual artefacts present in the slide images. Researchers are continuously striving to develop automatic machine-learning algorithms for processing medical images to assist in tumour detection. Nowadays, computer-based automated systems play an important role in cancer image analysis and help healthcare experts make rapid and correct inferences about the… More >

Shakra Mehak¹, M. Usman Ashraf², Rabia Zafar³, Ahmed M. Alghamdi⁴, Ahmed S. Alfakeeh⁵, Fawaz Alassery⁶, Habib Hamam⁷, Muhammad Shafiq^8,*

CMC-Computers, Materials & Continua, Vol.71, No.2, pp. 3407-3423, 2022, DOI:10.32604/cmc.2022.022705

Abstract Breast cancer (BC) is the most widely recognized cancer in women worldwide. By 2018, 627,000 women had died of breast cancer (World Health Organization Report 2018). To diagnose BC, the evaluation of tumours is achieved by analysis of histological specimens. At present, the Nottingham Bloom Richardson framework is the least expensive approach used to grade BC aggressiveness. Pathologists contemplate three elements, 1. mitotic count, 2. gland formation, and 3. nuclear atypia, which is a laborious process that witness's variations in expert's opinions. Recently, some algorithms have been proposed for the detection of mitotic cells, but nuclear atypia in breast cancer… More >