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  • Open Access

    ARTICLE

    Hierarchical Mixed-Effects and Stacked Machine Learning Ensembles with Data Augmentation for Leakage-Safe E-Waste Forecasting

    Hatim Madkhali1,2,*, Abdullah Sheneamer2, Linh Nguyen3, Gnana Bharathy1, Ritu Chauhan4, Mukesh Prasad1,*

    CMC-Computers, Materials & Continua, Vol.87, No.3, 2026, DOI:10.32604/cmc.2026.074444 - 09 April 2026

    Abstract Consumer electronics, with 62 million tons of electronic waste (e-waste) generated in 2022 and e-waste expected to grow to 82 million tons annually by 2030, pose critical challenges when it comes to national infrastructure and circular economy policies. This paper compares forecasting approaches using sparse panel data for 32 European countries (2005–2018, Eurostat/Waste Electrical and Electronic Equipment (WEEE) Directive), focusing on leakage-safe prospective validation to guarantee true predictive performance. We make one-step-ahead predictions with conservative features (primarily lagged values) to account for temporal autocorrelation but with reduced multicollinearity (Variance Inflation Factor (VIF) ≈ 1.0). Cross-paradigm comparisons… More >

  • Open Access

    REVIEW

    Ferroptosis as a Translational Axis in Small Cell Lung Cancer: A Systematic Review of Redox Pathways and Precision Oncology Prospects

    Donatella Coradduzza1,#, Anna La Salvia2,#, Giuseppe Fanciulli3, Maria Rosaria De Miglio3,*

    Oncology Research, Vol.34, No.4, 2026, DOI:10.32604/or.2025.073045 - 23 March 2026

    Abstract Background: An increasing number of studies have shown that ferroptosis is related to the initiation and development of small cell lung cancer (SCLC). The systematic review aimed to summarize the characteristics of ferroptosis from its pathogenetic role to translational therapeutic implications in SCLC. Methods: This systematic review, registered in PROSPERO (CRD420251090058), followed PRISMA 2020 guidelines. Comprehensive research of PubMed, Scopus, and Web of Science was performed for studies published between January 2010 and July 2025 investigating ferroptosis mechanisms, genetic or pharmacological modulation, or molecular profiling in SCLC. Two reviewers independently performed data extraction and quality… More >

  • Open Access

    REVIEW

    Artificial intelligence in urological malignancy diagnosis and prognosis: current status and future prospects

    Mingwei Zhan1,#, Zhaokai Zhou2,#, Jianpeng Zhang3,#, Xin Wang4, Canxuan Li5, Bochen Pan6, Zhanyang Luo7, Wenjie Shi8, Yongjie Wang9, Minglun Li10, Weizhuo Wang11,*, Run Shi12,*, Jingyu Zhu1,13,*

    Canadian Journal of Urology, Vol.33, No.1, pp. 35-49, 2026, DOI:10.32604/cju.2026.076084 - 28 February 2026

    Abstract Artificial intelligence (AI) is transforming the diagnostic landscape of malignant tumors in the urinary system, including prostate cancer, bladder cancer, and renal cell carcinoma (RCC). By integrating imaging, pathology, and molecular data, AI enhances the precision and reproducibility of tumor detection, grading, and risk stratification. In prostate cancer, AI-assisted multiparametric Magnetic resonance imaging (MRI) and digital pathology systems improve lesion localization and Gleason scoring. For bladder cancer, deep learning-based cystoscopy and radiomics models from Computed tomography/magnetic resonance imaging (CT/MRI) enable real-time lesion segmentation and non-invasive biomarker prediction, such as Programmed Cell Death-Ligand 1 (PD-L1) expression. More >

  • Open Access

    REVIEW

    Arrowroot Based Nanocomposite Films: Properties, Applications, and Sustainability Prospects: A Review

    Rasdianah Dahali1, Edi Syams Zainudin1,2,*, Mohammed Abdillah Ahmad Farid1, Tarique Jamal3, Mohd Sapuan Salit1,2, Muhammad Firdaus Abdul Halim2

    Journal of Renewable Materials, Vol.14, No.2, 2026, DOI:10.32604/jrm.2025.02025-0139 - 25 February 2026

    Abstract This review draws attention to the innovative use of arrowroot (Maranta arundinacea) fiber as a unique and underutilized biomass source for nanocrystalline cellulose (NCC)-based nanocomposites, presenting a noteworthy alternative to extensively researched materials like wood pulp, bacterial cellulose, and chemically modified NCCs. In contrast to traditional sources, arrowroot possesses a naturally elevated cellulose and diminished lignin content, facilitating more effective NCC extraction requiring reduced chemical input and enabling environmentally friendly processing techniques. The review evaluates the performance of arrowroot-derived nanocomposites against systems documented in the literature, including NCC-based shape memory composites and nanoparticle-reinforced films, demonstrating enhanced More > Graphic Abstract

    Arrowroot Based Nanocomposite Films: Properties, Applications, and Sustainability Prospects: A Review

  • Open Access

    REVIEW

    Male Breast Cancer: Epidemiology, Diagnosis, Molecular Mechanisms, Therapeutics, and Future Prospective

    Ashok Kumar Sah1,*, Ranjay Kumar Choudhary1,2, Velilyaeva Alie Sabrievna3, Karomatov Inomdzhon Dzhuraevich4, Anass M. Abbas5, Manar G. Shalabi5, Nadeem Ahmad Siddique6, Raji Rubayyi Alshammari7, Navjyot Trivedi8, Rabab H. Elshaikh1

    Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.068238 - 30 December 2025

    Abstract Male breast cancer (MBC) is rare, representing 0.5%–1% of all breast cancers, but its incidence is increasing due to improved diagnostics and awareness. MBC typically presents in older men, is human epidermal growth factor receptor 2 (HER2)-negative and estrogen receptor (ER)-positive, and lacks routine screening, leading to delayed diagnosis and advanced disease. Major risk factors include hormonal imbalance, radiation exposure, obesity, alcohol use, and Breast Cancer Gene 1 and 2 (BRCA1/2) mutations. Clinically, it may resemble gynecomastia but usually appears as a unilateral, painless mass or nipple discharge. Advances in imaging and liquid biopsy have More >

  • Open Access

    ARTICLE

    Prospects of Anthriscus, Chaerophyllum, and Myrrhoides Species Utilization and Biofortification with Selenium

    Nadezhda Golubkina1,*, Viktor Kharchenko1, Ekaterina Krainyuk2, Lubov Riff2, Vladimir Lapchenko3, Helene Lapchenko3, Anastasia Moldovan1, Uliana Plotnoikova4, Otilia Cristina Murariu5, Gianluca Caruso6

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 4139-4153, 2025, DOI:10.32604/phyton.2025.072328 - 29 December 2025

    Abstract Despite their remarkable content of biologically active compounds, highly valuable for human health, wild relatives of Umbelliferous plants show limited utilization. The aim of the present work was the evaluation of the antioxidant status of Anthriscus, Chaerophyllum, and Myrrhoides species gathered in different climatic zones (from Mediterranean to Arctic) and of their suitability to produce valuable functional food for optimizing the human Se status. Among the Crimean plants, A. sylvestris, C. bulbosis, and M. nososa showed the highest antioxidant status, while the lowest was recorded in A. cerefolium and A. caucalis, displaying a significant correlation between the antioxidant activity (AOA) and polyphenols… More >

  • Open Access

    COMMUNICATION

    A prospective randomized trial comparing dusting and fragmentation techniques using Holmium:YAG laser for pediatric ureteral stones

    Ahmed Ahmed1, Bilal Farhan2, Amr Alam-Eldin1, Maged Amin Helmy1, Mohammed Mostafa Hussein1, Zakieldahshoury Mohamed1, Hassaan A. Gad1, Suraj Nayan Vodnala3,*

    Canadian Journal of Urology, Vol.32, No.5, pp. 483-490, 2025, DOI:10.32604/cju.2025.067228 - 30 October 2025

    Abstract Background: As occurrence rates of pediatric ureteral stones have increased, evaluation of optimal treatment modalities has become imperative. This study’s primary goal is to compare outcomes between dusting and fragmentation techniques using Holmium:YAG (Ho:YAG) laser lithotripsy in children with ureteral stones. Methods: A prospective randomized study was conducted at Aswan University Hospitals from June 2023 to December 2024. One hundred children, under the age of 18, with single, mid- or distal, ureteral stones (5–20 mm) were randomized into two groups. Group A received laser dusting (0.2–0.6 J, 20–40 Hz), while Group B received fragmentation (0.8–1.5… More >

  • Open Access

    ARTICLE

    When friendship meets love: A short-term prospective study of opposite-sex friends need fulfillment effects on romantic relationship quality

    Xiaoyue Zhao1, Ting Wang2, Baoyan Yang3,*, Hongyu Zang1, Qifeng Gao1, Zhongyuan Zhang1, Birong Xing1

    Journal of Psychology in Africa, Vol.35, No.5, pp. 701-711, 2025, DOI:10.32604/jpa.2025.067155 - 24 October 2025

    Abstract This study explored the relationship between need fulfillment given by opposite-sex friends and romantic relationship quality, as well as the potential underlying mechanisms, including perceived quality of opposite-sex friend relationships, need fulfillment given by romantic partners and romantic desire towards opposite-sex friends. A total of 98 unmarried Chinese young adults in romantic relationships were participants (females = 45.9%; M = 22.71, SD = 2.81). The findings from regression, mediation, and moderation analyses indicated need fulfillment given by opposite-sex friends was associated with lower romantic relationship quality. Perceived quality of opposite-sex friend relationships mediated the relationship between… More >

  • Open Access

    REVIEW

    A Comprehensive Study on Application and Prospect of Hydrogel Detection Methods

    Caixia Chen1, Pengyu Liu1, Changhua Wang1, Yanyan Xie1, Wei Wang1,*, Xiaomin Kang2,*

    Journal of Polymer Materials, Vol.42, No.3, pp. 621-660, 2025, DOI:10.32604/jpm.2025.068852 - 30 September 2025

    Abstract Due to their high water content, stimulus responsiveness, and biocompatibility, hydrogels, which are functional materials with a three-dimensional network structure, are widely applied in fields such as biomedicine, environmental monitoring, and flexible electronics. This paper provides a systematic review of hydrogel characterization methods and their applications, focusing on primary evaluation techniques for physical properties (e.g., mechanical strength, swelling behavior, and pore structure), chemical properties (e.g., composition, crosslink density, and degradation behavior), biocompatibility, and functional properties (e.g., drug release, environmental stimulus response, and conductivity). It analyzes the challenges currently faced by characterization methods, such as a More >

  • Open Access

    REVIEW

    The Reductive Amination of Biomass-Based Aldehydes and Alcohols towards 2,5-bis(aminomethyl)furan: Progress, Challenges and Prospects

    Li Ji1,2, Jiawei Mao1,3, Ruixiang Li1,*, Jiaqi Xu1,*

    Journal of Renewable Materials, Vol.13, No.9, pp. 1683-1706, 2025, DOI:10.32604/jrm.2025.02025-0043 - 22 September 2025

    Abstract Primary diamines play an important role in the chemical industry, where they are widely used as raw materials for the manufacture of pharmaceuticals and polymers. Currently, primary diamines are mainly derived from petroleum, while harsh or toxic conditions are often needed. Biomass is abundant and renewable , which serves as a promising alternative raw material to produce primary diamines. This review primarily focuses on the synthesis of 2,5-bis(aminomethyl)furan (BAMF), a bio-based diamine with potential as a biomonomer for polyamides and polyureas. Specifically, this review emphasizes the synthesis of BAMF from three biomass-derived alcohols and aldehydes,… More > Graphic Abstract

    The Reductive Amination of Biomass-Based Aldehydes and Alcohols towards 2,5-bis(aminomethyl)furan: Progress, Challenges and Prospects

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