Mohit Dhanda¹, Pankaj Pant², Sourabh Dogra¹, Arpan Gupta^1,*, Varun Dutt³

Sound & Vibration, Vol.56, No.3, pp. 235-243, 2022, DOI:10.32604/sv.2022.015615

Abstract With the Internet of Things (IoT) era dawning in, we are surrounded by a plethora of sensors. The present paper focuses on MEMS-based vibration measuring accelerometers, which are ubiquitously present in smartphones, tablets, smartwatches/bands, etc. These contact type vibration sensors have the unique advantage of being very small, low cost, low power, less weighing, and easily accommodatable in electronics. However, the accuracy of these sensors needs to be quantified with respect to more accurate sensors. With this objective, the paper presents a comparison of the relative sensitivity of a MEMS-based accelerometer (MPU 6050), a Geophone, and a sensor from Xiaomi… More >

S. Pradeepkumar^*, P. Nagaraj

Sound & Vibration, Vol.56, No.3, pp. 221-233, 2022, DOI:10.32604/sv.2022.014889

Abstract Vibrational characteristics in small horizontal axis wind turbine system are presented in this study with a system concept called tactile response and substructuring. The main focus is on managing the dynamic properties like vibration, noise, and harshness that occur during the operational mode. Tactile response is defined as the response of subsystem which is induced when a human body touches a vibrating system. Sub structuring is a computational method used to reduce the dynamic behavior of a large complex system with a smaller number of degrees of freedom without disturbing the mesh size of the model. Sub structuring has the… More >

XINTING ZHU^1,2,#, MENG YE^2,3,#, KELAN FANG¹, FANG LIU^1,2, JING HUI^1,2, MEICHEN LIU², XIAOFEI LI^1,2, RONG YAN^1,2,*, Yun Liu^1,2,4,*

BIOCELL, Vol.46, No.12, pp. 2595-2600, 2022, DOI:10.32604/biocell.2022.025468

Abstract Cantharidin (CTD) is a bioactive ingredient isolated from Cantharis vesicatoria (blister beetles), which has potential therapeutic value as an anticancer agent. Magnesium Demethylcantharidate (MDC) is a recently developed derivative of Cantharidin (CTD), and previous studies have illustrated its excellent anticancer activity on HCC cells. However, the effect and mechanism of MDC remains unclear and need to be further studied. In particular, whether MDC can cause ER stress in HCC is still unknown. In this study, we demonstrated that endoplasmic reticulum stress (ERS)-related proteins were changed in SMMC-7721 and Bel-7402 cells after being exposed to MDC. Moreover, we found that MDC… More >

ALPASLAN OZTURK^1,*, MEHMET KARA²

BIOCELL, Vol.46, No.12, pp. 2625-2635, 2022, DOI:10.32604/biocell.2022.023124

Abstract In this study, our aim was to examine the diagnostic and prognostic significance of lymphocyte/C-reactive protein ratio (LCR), neutrophil/lymphocyte ratio (NLR) and D-dimer parameters in COVID-19 infection. The LCR, NLR, neutrophil count, mean platelet volume (MPV), C-reactive protein (CRP), and D-dimer parameters were evaluated retrospectively. This was a retrospective cohort study with 1000 COVID-19 positive and 1000 healthy control groups, all over the age of 18 years. Odds ratio (OR) and 95% confidence interval (CI) values were calculated for each parameter found to be statistically significant in the univariate and multivariate logistic regression models. Herein, 127 (12.7%) of the COVID-19⁺… More >

MONICA SAVIO, VALENTINA MINOIA, PAOLA FULGHIERI, LUCIA ANNA STIVALA^*, VIRGINIE SOTTILE^*

BIOCELL, Vol.46, No.12, pp. 2525-2530, 2022, DOI:10.32604/biocell.2022.022924

Abstract The nutraceutical resveratrol is associated with a range of biological effects, from antibiotic to anti-inflammatory activities. One major axis of research has sought to harness its anti-tumour potential, with promising preclinical results and early clinical trials. A second strong interest relies on the anti-ageing effects ascribed to the compound and its application to stem cell research. It is becoming clear however that these possible favourable effects are conditioned by a set concentration range not easily controllable in vivo. Here we evoke novel developments in the field that could lead to more reliable conditions for the translational use of resveratrol-based compounds. More >

FEI LIU¹, JIAZHANG WEI², JIAO LAN¹, YONGLI WANG², JIANXIANG YE³, CHENG Su¹, MINGZHENG MO¹, FENGZHU TANG², BING LI², MIN LI², WEIMING DENG², LINSONG YE², Wenlin HUANG², JINGJIN WENG², WEI JIAO^1,*, SHENHONG QU^2,*

BIOCELL, Vol.46, No.12, pp. 2659-2669, 2022, DOI:10.32604/biocell.2022.022886

Abstract Our previous studies suggested a potential interaction between the POK erythroid myeloid ontogenic factor ZBTB7A and glucose transporter 1 (GLUT1) in nasopharyngeal carcinoma (NPC). This study was designed to confirm the interaction and further evaluate the precise mechanism by which ZBTB7A and GLUT1 regulate NPC development. The binding sites between ZBTB7A and the promoter of GLUT1 were predicted by bioinformatics. Gene expression was measured by quantitative real-time polymerase chain reaction (qPCR), western blotting, and immunohistochemistry. The activities of key glycolysis enzymes, including hexokinase (HK), pyruvate kinase (PK), lactate dehydrogenase (LDH), and lactate, were detected using specific enzyme-linked immunosorbent assay kits.… More >

LIMIN YU^1,2, ZHONGFENG ZHANG^2,*, LONGWU ZHOU²

BIOCELL, Vol.46, No.12, pp. 2559-2573, 2022, DOI:10.32604/biocell.2022.022825

Abstract

Arbuscular mycorrhizal (AM) fungi reside in the rhizosphere and form mutualistic associations with plant roots. They promote photosynthesis, improve stress resistance, and induce secondary metabolite biosynthesis in host medicinal plants. The AM fungi that are symbiotic with medicinal plants comprise a wide array of species and have abundant germplasm resources. Though research on the AM fungi in medicinal plants began relatively recently, it has nonetheless become an investigative hot spot. Several scholars have explored the diversity and the growth-promoting effects of mycorrhizal fungi in hundreds of medicinal plants. Current research on symbiotic AM fungi in medicinal plants has focused mainly… More >

LAURA LAFON-HUGHES^1,2,*

BIOCELL, Vol.46, No.12, pp. 2531-2535, 2022, DOI:10.32604/biocell.2022.022713

Abstract Poly(ADP-ribose) (PAR) is a highly negatively charged polymer. PAR is synthesized by poly(ADP-ribose)polymerases (PARPs) and is involved in the assembly and stabilization of macromolecular complexes. Here, the presence and putative roles of poly(ADP-ribosyl)ation (PARylation) associated to adherens junctions (AJ) and the actin cytoskeleton in epithelial and Schwann cells, is reviewed. The hypothesis generated by analogy, stating that PAR is associated to AJ in other cell types, is postulated. According to this hypothesis, PAR associated to puncta adherentia in chemical synapses would participate in plasticity, learning and memory. In turn, PAR associated to fascia adherens in cardiomyocytes, would affect heart beating.… More >

SONIA MORETTI, FLAVIA MANCINI, ALESSANDRA BORSETTI^*

BIOCELL, Vol.46, No.12, pp. 2695-2699, 2022, DOI:10.32604/biocell.2022.022257

Abstract Direct-acting antiviral (DAA) therapies are efficacious for the achievement of sustained virologic response (SVR) in almost all treated hepatitis C virus (HCV)-infected patients. However, the impacts of HCV eradication on immune function and chronic immune activation in the long-term remain controversial and limited, especially in patients co-infected with human immunodeficiency virus (HIV). Indeed, although restoration of many immune responses clearly can be observed, several features of immune perturbations persist over time after HCV clearance. Understanding the degree and reasons of the partial recovery of the immune system in chronic HCV/HIV co-infection after HCV elimination is pivotal to avoid disease progression… More >

JÉRÔME LALOZE^1,2, ALEXIS DESMOULIÈRE^1,*

BIOCELL, Vol.46, No.12, pp. 2701-2704, 2022, DOI:10.32604/biocell.2022.022229

Abstract Advances in regenerative medicine correlate strongly with progress in the use of adipose tissue-derived mesenchymal stem/stromal cells. The range of therapeutic indications has also expanded over recent years. Numerous recent studies have highlighted the primary importance of paracrine secretion by these cells. Though it is interesting to compare the different types of such secretions, we believe that exosomes (extra-cellular vesicles possessing the same properties as their source cells) will likely be the main key in tomorrow’s cell therapy. Exosomes also have many advantages compared to the direct use of cells, making these particles a major target in fundamental and translational… More >