Mohammed Aly^1,*, Abdullah Shawan Alotaibi²

CMC-Computers, Materials & Continua, Vol.77, No.1, pp. 557-582, 2023, DOI:10.32604/cmc.2023.042493

Abstract Tumor segmentation is a valuable tool for gaining insights into tumors and improving treatment outcomes. Manual segmentation is crucial but time-consuming. Deep learning methods have emerged as key players in automating brain tumor segmentation. In this paper, we propose an efficient modified U-Net architecture, called EMU-Net, which is applied to the BraTS 2020 dataset. Our approach is organized into two distinct phases: classification and segmentation. In this study, our proposed approach encompasses the utilization of the gray-level co-occurrence matrix (GLCM) as the feature extraction algorithm, convolutional neural networks (CNNs) as the classification algorithm, and the chi-square method for feature selection.… More >

Tawfeeq Shawly¹, Ahmed Alsheikhy^2,*

CMC-Computers, Materials & Continua, Vol.77, No.1, pp. 425-443, 2023, DOI:10.32604/cmc.2023.040561

Abstract According to the World Health Organization (WHO), Brain Tumors (BrT) have a high rate of mortality across the world. The mortality rate, however, decreases with early diagnosis. Brain images, Computed Tomography (CT) scans, Magnetic Resonance Imaging scans (MRIs), segmentation, analysis, and evaluation make up the critical tools and steps used to diagnose brain cancer in its early stages. For physicians, diagnosis can be challenging and time-consuming, especially for those with little expertise. As technology advances, Artificial Intelligence (AI) has been used in various domains as a diagnostic tool and offers promising outcomes. Deep-learning techniques are especially useful and have achieved… More >

Xiaoliang Lei¹, Xiaosheng Yu^2,*, Hao Wu³, Chengdong Wu^2,*, Jingsi Zhang²

CMC-Computers, Materials & Continua, Vol.76, No.3, pp. 3797-3811, 2023, DOI:10.32604/cmc.2023.042069

Abstract Accurate tumor segmentation from brain tissues in Magnetic Resonance Imaging (MRI) imaging is crucial in the pre-surgical planning of brain tumor malignancy. MRI images’ heterogeneous intensity and fuzzy boundaries make brain tumor segmentation challenging. Furthermore, recent studies have yet to fully employ MRI sequences’ considerable and supplementary information, which offers critical a priori knowledge. This paper proposes a clinical knowledge-based hybrid Swin Transformer multimodal brain tumor segmentation algorithm based on how experts identify malignancies from MRI images. During the encoder phase, a dual backbone network with a Swin Transformer backbone to capture long dependencies from 3D MR images and a… More >

Vijey Thayananthan¹, Aiiad Albeshri², Hassan A. Alamri³, Muhammad Bilal Qureshi⁴, Muhammad Shuaib Qureshi^5,*

CMC-Computers, Materials & Continua, Vol.76, No.3, pp. 2573-2595, 2023, DOI:10.32604/cmc.2023.040184

Abstract Complex networks on the Internet of Things (IoT) and brain communication are the main focus of this paper. The benefits of complex networks may be applicable in the future research directions of 6G, photonic, IoT, brain, etc., communication technologies. Heavy data traffic, huge capacity, minimal level of dynamic latency, etc. are some of the future requirements in 5G+ and 6G communication systems. In emerging communication, technologies such as 5G+/6G-based photonic sensor communication and complex networks play an important role in improving future requirements of IoT and brain communication. In this paper, the state of the complex system considered as a… More >

Muhammad Attique Khan^1,2, Reham R. Mostafa³, Yu-Dong Zhang², Jamel Baili⁴, Majed Alhaisoni⁵, Usman Tariq⁶, Junaid Ali Khan¹, Ye Jin Kim⁷, Jaehyuk Cha^7,*

CMC-Computers, Materials & Continua, Vol.76, No.3, pp. 3029-3047, 2023, DOI:10.32604/cmc.2023.038838

Abstract Manual diagnosis of brain tumors using magnetic resonance images (MRI) is a hectic process and time-consuming. Also, it always requires an expert person for the diagnosis. Therefore, many computer-controlled methods for diagnosing and classifying brain tumors have been introduced in the literature. This paper proposes a novel multimodal brain tumor classification framework based on two-way deep learning feature extraction and a hybrid feature optimization algorithm. NasNet-Mobile, a pre-trained deep learning model, has been fine-tuned and two-way trained on original and enhanced MRI images. The haze-convolutional neural network (haze-CNN) approach is developed and employed on the original images for contrast enhancement.… More >

Kainat Nazir¹, Tahir Mustafa Madni¹, Uzair Iqbal Janjua¹, Umer Javed², Muhammad Attique Khan³, Usman Tariq⁴, Jae-Hyuk Cha^5,*

CMC-Computers, Materials & Continua, Vol.76, No.3, pp. 2861-2877, 2023, DOI:10.32604/cmc.2023.039181

Abstract Brain tumor significantly impacts the quality of life and changes everything for a patient and their loved ones. Diagnosing a brain tumor usually begins with magnetic resonance imaging (MRI). The manual brain tumor diagnosis from the MRO images always requires an expert radiologist. However, this process is time-consuming and costly. Therefore, a computerized technique is required for brain tumor detection in MRI images. Using the MRI, a novel mechanism of the three-dimensional (3D) Kronecker convolution feature pyramid (KCFP) is used to segment brain tumors, resolving the pixel loss and weak processing of multi-scale lesions. A single dilation rate was replaced… More >

Xinyi Xiao, Dongbo Pan^*, Jianjun Yuan

Intelligent Automation & Soft Computing, Vol.37, No.3, pp. 3179-3191, 2023, DOI:10.32604/iasc.2023.041208

Abstract Neurological disorders like Alzheimer’s disease have a significant impact on the lives and health of the elderly as the aging population continues to grow. Doctors can achieve effective prevention and treatment of Alzheimer’s disease according to the morphological volume of hippocampus. General segmentation techniques frequently fail to produce satisfactory results due to hippocampus’s small size, complex structure, and fuzzy edges. We develop a new SC-Net model using complete brain MRI images to achieve high-precision segmentation of hippocampal structures. The proposed network improves the accuracy of hippocampal structural segmentation by retaining the original location information of the hippocampus. Extensive experimental results… More >

Umair Muneer Butt^1,2,*, Rimsha Arif², Sukumar Letchmunan^1,*, Babur Hayat Malik², Muhammad Adil Butt²

CMC-Computers, Materials & Continua, Vol.76, No.2, pp. 2551-2570, 2023, DOI:10.32604/cmc.2023.039164

Abstract The detection of brain disease is an essential issue in medical and research areas. Deep learning techniques have shown promising results in detecting and diagnosing brain diseases using magnetic resonance imaging (MRI) images. These techniques involve training neural networks on large datasets of MRI images, allowing the networks to learn patterns and features indicative of different brain diseases. However, several challenges and limitations still need to be addressed further to improve the accuracy and effectiveness of these techniques. This paper implements a Feature Enhanced Stacked Auto Encoder (FESAE) model to detect brain diseases. The standard stack auto encoder’s results are… More >

Jingyu Wang^1,#, Yongrou Zhang^4,#, Zuyue Lei¹, Junqi Wang¹, Yangming Zhao¹, Taolin Sun^3,*, Zhenyu Jiang¹, Licheng Zhou¹, Zejia Liu¹, Yiping Liu¹, Bao Yang¹, Liqun Tang^1,2,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.25, No.4, pp. 1-1, 2023, DOI:10.32604/icces.2022.08829

Abstract In surgical training applications and experimental research, brain tissues immersed in cerebrospinal fluid often involve very complex deformation and strain rate effects, which affects their reliability and stability. Thus, it is indispensable to develop a high-fidelity human brain tissue simulant material as a physical surrogate model to understand their mechanical behavior, such as traumatic brain injury (TBI). However, the reported simulant materials have not yet been able to compare and satisfy the above two mechanical properties. Here, we developed a novel composite hydrogel with brain tissue-like mechanical properties and investigated their mechanical behavior in a solution environment. The results demonstrate… More >

LONGSHENG FU¹, JINFANG HU¹, FENG SHAO², YAOQI WU¹, WEI BAI³, MINGJIN JIANG³, HAO CHEN⁴, LIHUA CHEN², YANNI LV^1,*

BIOCELL, Vol.47, No.8, pp. 1869-1883, 2023, DOI:10.32604/biocell.2023.028602

Abstract Background: Biochanin A is an excellent dietary isoflavone that has the concomitant function of both medicine and foodstuff. The attenuation function of biochanin A on blood-brain barrier (BBB) damage induced by cerebral ischemia-reperfusion remains unclear. Methods: C57BL/6 mice were subjected to 1 h middle cerebral artery occlusion (MCAO) followed by 24 h reperfusion. The infarct volume of the brain was stained by TTC, while leakage of the brain was quantitatively stained by Evans blue, and the neurologic deficit score was measured. Microglial-induced morphologic changes were observed via immunofluorescence staining, and rolling and adhering leukocytes in venules were observed via two-photon… More >