TATIANA KURILO^*, REBECCA D. PENTZ

Oncology Research, Vol.32, No.9, pp. 1401-1406, 2024, DOI:10.32604/or.2024.050266

Abstract Objectives: Rural patients have poor cancer outcomes and clinical trial (CT) enrollment compared to urban patients due to attitudinal, awareness, and healthcare access differential. Knowledge of cancer survival disparities and CT enrollment is important for designing interventions and innovative approaches to address the stated barriers. The study explores the potential disparities in cancer survival rates and clinical trial enrollments in rural and urban breast and lung cancer patients. Our hypotheses are that for both cancer types, urban cancer patients will have longer 5-year survival rates and higher enrollment rates in clinical trials than those in… More >

Aleksandra Jeżo^*

Journal of Renewable Materials, Vol.12, No.6, pp. 1029-1042, 2024, DOI:10.32604/jrm.2024.051330

Abstract Bark extracts are sustainable sources of biopolymers and hold great promise for replacing fossil fuel-based polymers, for example, in wood-based composites. In addition to primary and secondary metabolites, tree bark also contains suberin, which plays a major role in protecting the tree from environmental conditions. Suberin is a natural aliphatic-aromatic cross-linked polyester present in the cell walls of both normal and damaged external tissues, the main component of which are long-chain aliphatic acids. Its main role as a plant ingredient is to protect against microbiological factors and water loss. One of the most important suberin More >

Ponusa Songtipya^1,2,*, Thummanoon Prodpran^1,2, Ladawan Songtipya^1,2, Theerarat Sengsuk¹

Journal of Renewable Materials, Vol.12, No.5, pp. 951-967, 2024, DOI:10.32604/jrm.2024.049068

Abstract The synergistic effect of organoclay (OC) and zinc oxide (ZnO) nanoparticles on the crucial properties of poly(lactic acid) (PLA) nanocomposite films was systematically investigated herein. After their incorporation into PLA via the solvent casting technique, the water vapor barrier property of the PLA/OC/ZnO film improved by a maximum of 86% compared to the neat PLA film without the deterioration of Young’s modulus or the tensile strength. Moreover, the film’s self-antibacterial activity against foodborne pathogens, including gram-negative (Escherichia coli, E. coli) and gram-positive (Staphylococcus aureus, S. aureus) bacteria, was enhanced by a maximum of approximately 98–99% compared to the neat… More > Graphic Abstract

Jiawei Qin^1,2, Hua Zhang^1,*, Hanbing Yan², Tian Zhu², Song Hu¹, Dingyu Yan²

Intelligent Automation & Soft Computing, Vol.39, No.3, pp. 527-544, 2024, DOI:10.32604/iasc.2024.047509

Abstract By the analysis of vulnerabilities of Android native system services, we find that some vulnerabilities are caused by inconsistent data transmission and inconsistent data processing logic between client and server. The existing research cannot find the above two types of vulnerabilities and the test cases of them face the problem of low coverage. In this paper, we propose an extraction method of test cases based on the native system services of the client and design a case construction method that supports multi-parameter mutation based on genetic algorithm and priority strategy. Based on the above method, More >

Aneel Manan¹, Pu Zhang^1,*, Shoaib Ahmad², Jawad Ahmad²

Journal of Polymer Materials, Vol.41, No.1, pp. 15-44, 2024, DOI:10.32604/jpm.2024.053859

Abstract Fiber-reinforced polymer (FRP) bars are gaining popularity as an alternative to steel reinforcement due to their advantages such as corrosion resistance and high strength-to-weight ratio. However, FRP has a lower modulus of elasticity compared to steel. Therefore, special attention is required in structural design to address deflection related issues and ensure ductile failure. This research explores the use of machine learning algorithms such as gene expression programming (GEP) to develop a simple and effective equation for predicting the elastic modulus of hybrid fiber-reinforced polymer (HFPR) bars. A comprehensive database of 125 experimental results of HFPR… More >

Rafidah Md Salim^1,2,*, Jahimin Asik², Mohd Sani Sarjadi²

Journal of Renewable Materials, Vol.12, No.4, pp. 737-769, 2024, DOI:10.32604/jrm.2024.045695

Abstract Lignin extraction from bark can maximize the utilization of biomass waste, offer cost-effectiveness, and promote environmental friendliness when employed as an adhesive material in bark particleboard production. Particles of fine (0.2 to 1.0 mm), medium (1.0 to 2.5 mm), and coarse (2.5 to 12.0 mm) sizes, derived from the bark of Leucaena leucocephala, were hot-pressed using a heating plate at 175°C for 7 min to create single-layer particleboards measuring 320 mm × 320 mm × 10 mm, targeting a density of 700 kg/m. Subsequently, the samples were trimmed and conditioned at 20°C and 65% relative humidity.… More > Graphic Abstract

Ali S. Alghamdi^1,*, Mohamed A. Zohdy², Saad Aldoihi^3,4

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1339-1370, 2024, DOI:10.32604/cmes.2024.048839

Abstract In the contemporary era, the global expansion of electrical grids is propelled by various renewable energy sources (RESs). Efficient integration of stochastic RESs and optimal power flow (OPF) management are critical for network optimization. This study introduces an innovative solution, the Gaussian Bare-Bones Levy Cheetah Optimizer (GBBLCO), addressing OPF challenges in power generation systems with stochastic RESs. The primary objective is to minimize the total operating costs of RESs, considering four functions: overall operating costs, voltage deviation management, emissions reduction, voltage stability index (VSI) and power loss mitigation. Additionally, a carbon tax is included in… More >

Caiping Huang^*, Zihan Huang, Wenfeng You

Structural Durability & Health Monitoring, Vol.18, No.3, pp. 299-320, 2024, DOI:10.32604/sdhm.2024.047850

Abstract This paper presents an easily installed improved perfobond connector (PBL) designed to reduce the shear concentration of PBL. The improvement of PBL lies in changing the straight penetrating rebar to the Z-type penetrating rebar. To study the shear performance of improved PBL, two PBL test specimens which contain straight penetrating rebar and six improved PBL test specimens which contain Z-type penetrating rebars were designed and fabricated, and push-out tests of these eight test specimens were carried out to investigate and compare the shear behavior of PBL. Additionally, Finite Element Analysis (FEA) models of the PBL… More >

KARAN WADHWA¹, PAYAL CHAUHAN¹, SHOBHIT KUMAR², RAKESH PAHWA^3,*, RAVINDER VERMA⁴, RAJAT GOYAL⁵, GOVIND SINGH¹, ARCHANA SHARMA⁶, NEHA RAO³, DEEPAK KAUSHIK^1,*

Oncology Research, Vol.32, No.5, pp. 877-897, 2024, DOI:10.32604/or.2024.047278

Abstract Background: Glioblastoma multiforme (GBM) is recognized as the most lethal and most highly invasive tumor. The high likelihood of treatment failure arises from the presence of the blood-brain barrier (BBB) and stem cells around GBM, which avert the entry of chemotherapeutic drugs into the tumor mass. Objective: Recently, several researchers have designed novel nanocarrier systems like liposomes, dendrimers, metallic nanoparticles, nanodiamonds, and nanorobot approaches, allowing drugs to infiltrate the BBB more efficiently, opening up innovative avenues to prevail over therapy problems and radiation therapy. Methods: Relevant literature for this manuscript has been collected from a comprehensive More > Graphic Abstract

XUHUI ZHAO^1,2, XIAOMIN HUANG¹, CHUNYAN DANG², XIA WANG¹, YUJIAO QI³, HONGLING LI^2,*

Oncology Research, Vol.32, No.5, pp. 999-1009, 2024, DOI:10.32604/or.2024.046679

Abstract Background: EBV-miR-BARTs exhibit significant relevance in epithelial tumors, particularly in EBV-associated gastric and nasopharyngeal cancers. However, their specific mechanisms in the initiation and progression of gastric cancer remain insufficiently explored. Material and Methods: Initially, EBV-miRNA-BART6-5p and its target gene SMAD4 expression were assessed in EBV-associated gastric cancer tissues and cell lines. Subsequent transfection induced overexpression of EBV-miRNA-BART6-5p in AGS and MKN-45, and downregulation in EBV-positive cells (SUN-719). The subsequent evaluation aimed to observe their impact on gastric cancer cell proliferation, migration, and glycolytic processes, with the TGF-β/SMAD4 signaling pathway value clarified using a TGF-β inhibitor. Results:… More >