Virna Margarita Martín Giménez¹, SebastiáN GarcíA MenéNdez^2,3, Luiz Gustavo A. Chuffa⁴, Vinicius Augusto SimãO⁴, Russel J. Reiter⁵, Ramaswamy Sharma⁶, Walter Balduini⁷, Carla Gentile⁸, Walter Manucha^2,3,*

BIOCELL, Vol.49, No.12, pp. 2245-2282, 2025, DOI:10.32604/biocell.2025.071830 - 24 December 2025

Abstract Neurodegenerative diseases (NDs) such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS) are characterized by progressive neuronal loss, which is closely linked to mitochondrial dysfunction. These pathologies involve a complex interplay of genetics, protein misfolding, and cellular stress, culminating in impaired energy metabolism, an increase in reactive oxygen species (ROS), and defective mitochondrial quality control. The accumulation of damaged mitochondria and dysregulation of pathways such as the Integrated Stress Response (ISR) are central to the pathogenesis of these conditions. This review explores the critical relationship between mitochondrial stress… More >

Kezheng Gao¹, Shuaifei Li¹, Qingyuan Niu², Xiaojing Zhang^2,*

Journal of Renewable Materials, Vol.13, No.12, pp. 2309-2353, 2025, DOI:10.32604/jrm.2025.02025-0108 - 23 December 2025

Abstract The current global shortage of oil resources and the pollution problems caused by traditional barrier materials urgently require the search for new substitutes. Biodegradable bio-based barrier materials possess the characteristics of being renewable, environmentally friendly, and having excellent barrier properties. They have become an important choice in fields such as food packaging, agricultural film covering, and medical protection. This review systematically analyzes the design and research of this type of material, classifying biobased and biodegradable barrier materials based on the sources of raw materials and synthesis pathways. It also provides a detailed introduction to the More >

Lijuan Zhang¹, Yu Zhou², Jiawei Tian^3,*, Fupei Guo⁴, Xiang Zhang⁴, Bo Yang^4,*

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 3949-3968, 2025, DOI:10.32604/cmes.2025.071869 - 23 December 2025

Abstract In endoscopic surgery, the limited field of view and the nonlinear deformation of organs caused by patient movement and respiration significantly complicate the modeling and accurate tracking of soft tissue surfaces from endoscopic image sequences. To address these challenges, we propose a novel Hybrid Triangular Matching (HTM) modeling framework for soft tissue feature tracking. Specifically, HTM constructs a geometric model of the detected blobs on the soft tissue surface by applying the Watershed algorithm for blob detection and integrating the Delaunay triangulation with a newly designed triangle search segmentation algorithm. By leveraging barycentric coordinate theory, More >

Shahin Imran^1,2, Maki Katsuhara^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3653-3665, 2025, DOI:10.32604/phyton.2025.073959 - 01 December 2025

Abstract Barley (Hordeum vulgare L.) employs the Na⁺ transporter HvHKT1;1, which is an N⁺-selective transporter. This study characterized the full-length HvHKT1;1 (HvHKT1;1-FL) and three mRNA variants (HvHKT1;1-V1, -V2, and -V3), which encode polypeptides of 64.7, 54.0, 40.5, and 32.9 kDa, respectively. Tissue-specific expression profiling revealed that HvHKT1;1-FL is the most abundant transcript across leaf, sheath, and root tissues under normal conditions, with the highest expression in leaves. Under 150 mM NaCl stress, HvHKT1;1-FL and its variants showed a dynamic, time-dependent expression pattern, with peak leaf expression at 2 h, sheath expression at 12 h, and root expression at 2 h, suggesting their… More >

Su Li¹, Nooreen Noordin², Dan Wang^3,*

International Journal of Mental Health Promotion, Vol.27, No.11, pp. 1797-1812, 2025, DOI:10.32604/ijmhp.2025.072301 - 28 November 2025

Abstract Background: Communication barriers are a critical yet underexplored determinant of psychological well-being in oncology care, particularly among rural Chinese patients treated in urban hospitals. This study examined how Mandarin proficiency influences emotional distress and identified implications for mental health promotion. Methods: A sequential mixed-methods design was adopted. Quantitative data were collected from 180 rural cancer patients using the Putonghua Proficiency Test (PSC), the Hospital Anxiety and Depression Scale (HADS), and the Distress Thermometer (DT). Multiple linear regressions estimated covariate-adjusted associations between Mandarin proficiency and distress outcomes, controlling for demographic and clinical factors. Semi-structured interviews with 20… More >

Yang Lei^1,*, Bo Jiang¹, Yucai Zhao², Gaofeng Fu³, Falin Qi¹, Tian Tian¹, Qiankuan Feng¹, Qiming Qu¹

Structural Durability & Health Monitoring, Vol.19, No.6, pp. 1657-1679, 2025, DOI:10.32604/sdhm.2025.069415 - 17 November 2025

Abstract Detecting internal defects, particularly voids behind linings, is critical for ensuring the structural integrity of aging high-speed rail (HSR) tunnel networks. While ground-penetrating radar (GPR) is widely employed, systematic quantification of performance boundaries for air-coupled (A-CGPR) and ground-coupled (G-CGPR) systems within the complex electromagnetic environment of multilayer reinforced HSR tunnels remains limited. This study establishes physics-based quantitative performance limits for A-CGPR and G-CGPR through rigorously validated GPRMax finite-difference time-domain (FDTD) simulations and comprehensive field validation over a 300 m operational HSR tunnel section. Key performance metrics were quantified as functions of: (a) detection distance (A-CGPR:… More >

Andrea Panunzio¹, Rossella Orlando¹, Federico Greco^2,3, Giovanni Mazzucato⁴, Floriana Luigina Rizzo¹, Serena Domenica D’Elia¹, Antonio Benito Porcaro⁵, Alessandro Antonelli⁵, Alessandro Tafuri^1,6,*

Canadian Journal of Urology, Vol.32, No.5, pp. 375-384, 2025, DOI:10.32604/cju.2025.066140 - 30 October 2025

Abstract Background: The Barthel Index (BI) measures the level of patient independence in activities of daily living. This review aims to summarize current evidence on the use of the BI in urology, highlighting its potential as a tool for assessing patients prior to surgery. Materials and methods: A comprehensive search of PubMed, Scopus, and Web of Science databases was conducted for studies evaluating the BI in patients undergoing urologic surgery, following Systematic Review and Meta-analyses (PRISMA) guidelines. The BI was investigated both as a descriptor of baseline or postoperative health status and a prognostic indicator. A qualitative… More >

Beth Steinberg^1,*, Yulia Mulugeta¹, Catherine Quatman-Yates², Maeghan Williams², Anvitha Gogineni¹, Maryanna Klatt¹

International Journal of Mental Health Promotion, Vol.27, No.9, pp. 1237-1264, 2025, DOI:10.32604/ijmhp.2025.067232 - 30 September 2025

Abstract Background: Community-based first responders face high levels of workplace stressors that can profoundly impact their physical and mental health. Mindfulness-based interventions have shown promise in decreasing stress and increasing psychological resilience; however, implementation is difficult due to unpredictability of the job, department culture, and generational preferences. The objective of this qualitative study was to identify and enhance understanding of the specific needs and potential barriers and facilitators for the implementation of mindfulness-based programming for community-based first responders. Methods: A phenomenological qualitative study design was used to gain insights into the lived experiences of first responders… More >

Qiang Sun^1,2,*, Zheng-Song Qiu¹, Tie Geng², Han-Yi Zhong¹, Weili Liu², Yu-Lin Tang², Jin-Cheng Dong²

Journal of Polymer Materials, Vol.42, No.3, pp. 757-772, 2025, DOI:10.32604/jpm.2025.069808 - 30 September 2025

Abstract Addressing the critical challenges of viscosity loss and barite sag in synthetic-based drilling fluids (SBDFs) under high-temperature, high-pressure (HTHP) conditions, this study innovatively developed a hyperbranched amide polymer (SS-1) through a unique stepwise polycondensation strategy. By integrating dynamic ionic crosslinking for temperature-responsive rheology and rigid aromatic moieties ensuring thermal stability beyond 260°C, SS-1 achieves a molecular-level breakthrough. Performance evaluations demonstrate that adding merely 2.0 wt% SS-1 significantly enhances key properties of 210°C-aged SBDFs: plastic viscosity rises to 45 mPa·s, electrical stability (emulsion voltage) reaches 1426 V, and the sag factor declines to 0.509, outperforming conventional More >

Zhiyuan Zhang¹, Meng Shuai², Bin Wang¹, Ying He³, Fan Yang¹, Liyan Ren^4,*, Yuyuan Zhang⁴, Ziren Wang⁴

Energy Engineering, Vol.122, No.10, pp. 4169-4194, 2025, DOI:10.32604/ee.2025.066793 - 30 September 2025

Abstract With the rapid development of renewable energy, the Microgrid Coalition (MGC) has become an important approach to improving energy utilization efficiency and economic performance. To address the operational optimization problem in multi-microgrid cooperation, a cooperative game strategy based on the Nash bargaining model is proposed, aiming to enable collaboration among microgrids to maximize overall benefits while considering energy trading and cost optimization. First, each microgrid is regarded as a game participant, and a multi-microgrid cooperative game model based on Nash bargaining theory is constructed, targeting the minimization of total operational cost under constraints such as More >