A. O. Onwudiwe, C. I. Onyemaechi^*, S. C. Achebe, P. O. Philip, O. A. Ugwu

Journal of Psychology in Africa, Vol.35, No.6, pp. 843-851, 2025, DOI:10.32604/jpa.2025.069734 - 30 December 2025

Abstract Despite high burden of mental disorders in Nigeria, access to care remains critically limited, with stigma, inadequate infrastructure, and economic constraints posing significant barriers. Integration of mental health and technology offers unprecedented opportunities to bridge this treatment gap. This paper explores the potential of digital mental health interventions like mobile applications and teletherapy, as viable solutions through which mental health services could be expanded. Leveraging Nigeria’s growing digital ecosystem and mobile phone penetration, these innovations can provide scalable, cost-effective, and culturally relevant interventions, particularly in underserved areas. However, challenges such as digital literacy gaps, socio-cultural More >

Bruno Špiljak^1,#, Bojan Poposki^2,#, Stjepanka Lešić^3,*

Oncology Research, Vol.33, No.11, pp. 3269-3292, 2025, DOI:10.32604/or.2025.068395 - 22 October 2025

Abstract Head and neck squamous cell carcinoma (HNSCC) is an aggressive cancer with high recurrence rates and prevalent resistance to therapeutic interventions. Tumor behavior is largely dependent on the tumor microenvironment (TME) that includes immune cells, stromal components, cancer-associated fibroblasts (CAFs), the extracellular matrix (ECM), and an associated cytokine network. In this review, we examine principal mechanisms of the tumorigenic transformation, encompassing immune checkpoint disruption, therapy resistance mediated through CAFs, the contribution of hypoxic niches, and several metabolic dependencies that hold potential as future targets. Novel therapeutics developed and/or repurposed, such as immune checkpoint inhibitors (ICIs),… More >

Md. Tanvir Raihan¹, Md. Himel Mahmud², Badhon Chandra Mazumder², Md. Nazif Hasan Chowdhury³, Mohammad Tajul Islam^1,*

Journal of Polymer Materials, Vol.42, No.3, pp. 677-711, 2025, DOI:10.32604/jpm.2025.068356 - 30 September 2025

Abstract Electrospinning has gained significant importance across various fields, including biomedicine, filtration, and packaging due to the control it provides over the properties of the resulting materials, such as fiber diameter and membrane thickness. Chitosan is a biopolymer that can be utilized with both natural and synthetic copolymers, owing to its therapeutic potential, biocompatibility, and biodegradability. However, producing electrospun chitosan is challenging due to its high solution viscosity, which often results in the formation of beads instead of uniform fibers. To address this issue, the spinnability of chitosan is significantly enhanced, and the production of continuous More >

Livanshee Gupta¹, Nouha Haoudi^2,3,*, Lanjelina Oinam¹, Ananya Mahajan¹, Sonia Morya^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.9, pp. 2669-2700, 2025, DOI:10.32604/phyton.2025.065058 - 30 September 2025

Abstract The trends of consuming or using eco-friendly, biodegradable products due to the change in the lifestyle of the people have led to the exploration of new sources from plants or animals. Seed mucilage (SeM) is an underexplored component of plants that can be brought into play to deal with such problems. Mucilage, a viscous polysaccharide that can be obtained when seeds like chia, flax, garden cress, and tomato get hydrated and form a slimy, gel-like substance around the seed coat, can be utilized due to its unique characteristics. It has been used in developing many… More >

Neha Raina¹, Radha Rani², Mahika Kanojia², Avril Mathias³, Keshav Raj Paudel^4,*, Ashish Garg⁵, Hardeep Singh Tuli⁶, A. T. M. Mijanur Rahman⁷, Vetriselvan Subramaniyan⁸, Madhu Gupta^2,*

Oncology Research, Vol.33, No.10, pp. 2787-2831, 2025, DOI:10.32604/or.2025.066624 - 26 September 2025

Abstract Breast cancer is among the most prevalent cancers in females globally and has the highest mortality rate. The emergence of pharmacologic resistance in breast cancer is a significant challenge for researchers in the pursuit of effective treatment. Investigations in cancer nanotechnology have been transformed by the advancement of smart polymers, lipids, and inorganic materials. Research is now being conducted in the field of innovative nano-pharmaceutical formulations aimed at enhancing the efficacy and durability of chemotherapy. Nanotechnology-based delivery systems are beneficial for combating breast cancer due to theranostic applications, augmented drug encapsulation, decreased degradation, and minimal… More >

Saranya Velmurugan¹, Dapkupar Wankhar², Vijayalakshmi Paramasivan³, Gowtham Kumar Subbaraj^1,*

BIOCELL, Vol.49, No.8, pp. 1363-1390, 2025, DOI:10.32604/biocell.2025.065891 - 29 August 2025

Abstract Cancer rates are increasing globally, making it more urgent than ever to enhance research and treatment strategies. This study aims to investigate how innovative technology and integrated multi-omics techniques could help improve cancer diagnosis, knowledge, and therapy. A complete literature search was undertaken using PubMed, Elsevier, Google Scholar, ScienceDirect, Embase, and NCBI. This review examined the articles published from 2010 to 2025. Relevant articles were found using keywords and selected using inclusion criteria New sequencing methods, like next-generation sequencing and single-cell analysis, have transformed our ability to study tumor complexity and genetic mutations, paving the… More >

Nasmi Herlina Sari^1,*, Suteja¹, Widya Fatriasari²

Journal of Renewable Materials, Vol.13, No.8, pp. 1521-1546, 2025, DOI:10.32604/jrm.2025.02024-0058 - 22 August 2025

Abstract Composites made from biopolymers and natural fibers are gaining popularity as alternative sustainable structural materials. Biopolyesters including polylactic acid (PLA), polybutylene succinate (PBS), and polyhydroxyalkanoate (PHA), when mixed with natural fibers such as kenaf, hemp, and jute, provide an environmentally acceptable alternative to traditional fossil-based materials. This article examines current research on developments in the integration of biopolymers with natural fibers, with a focus on enhancing mechanical, thermal, and sustainability. Innovative approaches to surface treatment of natural fibers, such as biological and chemical treatments, have demonstrated enhanced adhesion with biopolymer matrices, increasing attributes such as… More > Graphic Abstract

Zhiying Sun¹, Guolong Zhao^2,3, Feng Hu^1,*

Journal of Psychology in Africa, Vol.35, No.4, pp. 513-521, 2025, DOI:10.32604/jpa.2025.070126 - 17 August 2025

Abstract This study examined the relationship between transformational leadership and employee bootleg innovation through the mediating role of creative self-efficacy and the moderating role of leader-member exchange (LMX). Data were collected from 279 employees and 56 matched supervisors within a large Chinese digital transformation group. A moderated mediation model analysis found that transformational leadership predicts higher employee bootleg innovation. Creative self-efficacy mediated the positive relationship between transformational leadership and employee bootleg. Additionally, leader-member exchange significantly moderated the relationship between transformational leadership and creative self-efficacy, for a further enhancement of bootleg innovation. These findings underscore the importance More >

Pallabi Biswas^1,#, Samarendra Nath Sur^2,#,*, Rabindranath Bera³, Agbotiname Lucky Imoize⁴, Chun-Ta Li^5,*

CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.1, pp. 83-146, 2025, DOI:10.32604/cmes.2025.067724 - 31 July 2025

Abstract Automotive radar has emerged as a critical component in Advanced Driver Assistance Systems (ADAS) and autonomous driving, enabling robust environmental perception through precise range-Doppler and angular measurements. It plays a pivotal role in enhancing road safety by supporting accurate detection and localization of surrounding objects. However, real-world deployment of automotive radar faces significant challenges, including mutual interference among radar units and dense clutter due to multiple dynamic targets, which demand advanced signal processing solutions beyond conventional methodologies. This paper presents a comprehensive review of traditional signal processing techniques and recent advancements specifically designed to address… More > Graphic Abstract

Arun Kumar¹, Revanasiddappa Moolemane¹, Thulasi Rajendran², Suresh Babu Naidu Krishna^3,4,*

Journal of Renewable Materials, Vol.13, No.7, pp. 1315-1346, 2025, DOI:10.32604/jrm.2025.02024-0050 - 22 July 2025

Abstract In the past two decades, nanocellulose has become an innovative material with unique properties. This substance has exceptional mechanical strength, an extensive surface area, and biodegradability. Collaborative integration of nanocellulose offers a more environmentally friendly solution to the current limitations by substituting carbon. Due to its versatility, nanocellulose is commonly employed in various industrial sectors, including paints, adhesives, paper production, and biodegradable polymers. Such versatility enables the creation of customized structures for potential use in emulsion and dispersion applications. Given its biocompatibility and nontoxicity, nanocellulose is particularly well-suited for biomedical purposes such as tissue engineering, More > Graphic Abstract