Open Access

CASE REPORT

Khaled Elenizi¹, Abdullah Sharaf Aldeen², Nasser Alotaibi^3,*, Nagy Fagir², Hussien Hado², Mubarak Aldossari²
Congenital Heart Disease, DOI:10.32604/chd.2025.071226
Abstract Persistent left superior vena cava (PLSVC) is a rare congenital anomaly that may complicate cardiac procedures when associated with a dilated coronary sinus (CS) and conduction disturbances. We report the case of a 27-year-old male with Wilson’s disease who presented with complete heart block. Echocardiography showed biatrial enlargement and severe CS dilation, while contrast-enhanced computed tomography (CT) confirmed PLSVC draining into the CS without a bridging vein. Anatomical constraints prevented cardiac resynchronization therapy, and dual-chamber pacemaker implantation proved technically challenging due to lead placement difficulties. This case highlights the importance of thorough preoperative assessment and More >

View

72

Download

14

Open Access

ARTICLE

Dehua Wu^*, Yanxuan Shi, Weixing Wang, Jiawen Tang, Tao Zhu, Guoqing Ding
Congenital Heart Disease, DOI:10.32604/chd.2025.070946
Abstract Objective: The correlation between intraoperative blood pressure thresholds and the incidence of severe adverse postoperative outcomes in geriatric patients undergoing noncardiac surgery remains inadequately characterized. This study aims to assess the association between intraoperative hypotension (IOH) parameters—specifically blood pressure thresholds and duration—and severe adverse outcomes in geriatric patients. Methods: A retrospective evaluation was performed on 846 elderly patients who underwent non-cardiac surgical procedures at Shanghai Songjiang District Hospital in China, from 01 January 2020, to 31 December 2021. Forty-one patients meeting specific exclusion criteria were excluded from the analysis, yielding a final sample size of 805.… More >

View

10

Download

2

Open Access

ARTICLE

Gui-lian He^1,2, Jun Chen¹, Zhong-yong Liu², Zeng-guang Fan², Ping Liu^1,3,*
Congenital Heart Disease, DOI:10.32604/chd.2025.067855
Abstract Background: Chronic heart failure (CHF) is a major cardiovascular disease linked to mental health, lifestyle, and socioeconomic factors. This study aims to assess the causal relationships between genetically predicted anxiety, depression, their influencing factors, and CHF risk. Methods: A two-sample bidirectional mendelian randomization (MR) analysis was conducted using genetic variants from large-scale GWAS as instrumental variables. Exposures included genetically predicted anxiety, depression, C-reactive protein (CRP), interleukin-6 (IL-6), smoking, physical activity, education level, and socioeconomic factors (number in household, and number of vehicles in a household). Causal effects were assessed using inverse variance weighted (IVW), MR-Egger, Simple… More >

View

360

Download

82

Open Access

ARTICLE

Lanqing Qu^1,2,#, Jinbiao Zhang^1,2,#, Wei Jiang^1,2, Jiayu Zhang^1,2, Die Li¹, Wei Cheng³, Linghua Tao⁴, Hongdan Zhu⁵, Jing Li⁶, Min Xue⁷, Feng Chen⁸, Cuicui Xu⁹, Qiang Shu^1,2,*, Weize Xu^1,2,*
Congenital Heart Disease, DOI:10.32604/chd.2025.066258
Abstract Background: Congenital heart disease (CHD) is the most common congenital anomaly, but whether the COVID-19 pandemic affects its prevalence is unknown. We aimed to compare the incidence of CHD during the COVID-19 pandemic with that before the pandemic in China. Methods: This multicenter retrospective observational study involved all newborns in seven representative cities of China between 01 September 2019, and 31 December 2021. All the newborns underwent pulse oximetry monitoring combined with cardiac murmur auscultation in the first 6 h to 72 h after birth for CHD screening. We defined fetuses born in and beyond September… More >

View

342

Download

109