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  • Open Access

    ARTICLE

    Evaluation of Post-Operative Atrial Fibrillation after Cardiac Surgery for Adult Congenital Heart Disease

    Jonathan S. Taylor-Fishwick1,*, Nicholas Holzemer2, Brandon Middlemist3, Vivian Duarte3, Kaitlin E. Olson4, Johannes C. von Alvensleben5, Megan SooHoo6, Amber Khanna7
    Congenital Heart Disease, DOI:10.32604/chd.2024.057151
    Abstract Background: Post-operative atrial fibrillation (POAF) frequently occurs after cardiac surgery. Although adult congenital heart disease (ACHD) patients have higher rates of arrhythmia than the general population, there is scant literature on POAF in ACHD patients. Objectives: Identify key risk factors associated with post-operative atrial fibrillation and evaluate the short- and mid-term significance of developing POAF. Methods: A retrospective cohort study was conducted of ACHD patients from 2013–2021 at the University of Colorado Hospital and Children’s Hospital of Colorado. The institutional Society of Thoracic Surgeons (STS) surgical registry was used to identify patients ≥18-year-old with congenital heart… More >

  • Open Access

    REVIEW

    Right Axillary Thoracotomy Should Be the Standard of Care for Repair of Non-Complex Congenital Heart Defects in Infants and Children

    Sameh M. Said1,2,*, Yasin Essa1
    Congenital Heart Disease, DOI:10.32604/chd.2024.055636
    Abstract Minimally invasive approaches for cardiac surgery in children have been lagging in comparison to the adult world. A wide range of the most common congenital heart defects in infants and children can be repaired successfully through a variety of non-sternotomy incisions. This has been shown to be associated with superior cosmetic results, shorter hospital stays, and rapid return to full activity compared to sternotomy. These approaches have been around for decades, but they have not been widely adopted for a variety of reasons. Right axillary thoracotomy is one of these approaches that we believe should More >

  • Open Access

    ARTICLE

    Temporal and Regional Differences in Congenital Heart Surgery in China (2017–2022): Trends and Implications

    Zheng Guo1, Li Xie2, Ju Zhao3, Xing Hao3, Xiaotong Hou3, Wei Wang1,*
    Congenital Heart Disease, DOI:10.32604/chd.2024.057403
    Abstract Background: With the decline of birth population and the development of medical technology in China, studies assessing how these changes have affected the adoption of congenital heart disease surgery at the national or regional scale are lacking. Methods: We investigated the status of congenital heart surgery in China in the period from 2017–2022, through investigation of the total rates of cardiac surgeries, cardiopulmonary bypass (CPB), adult congenital heart surgeries (CHS), and pediatric CHS (<18 years old), as recorded by the Extracorporeal Circulation Branch of the Chinese Society of Biomedical Engineering. Subsequently, we evaluated correlations between… More >

  • Open Access

    REVIEW

    The Potential of Circular RNAs as Biomarkers in Pulmonary Arterial Hypertension Related to Congenital Heart Disease

    Fajri Marindra Siregar1,2, Sofia Mubarika Haryana3, Dyah Wulan Anggrahini4, Lucia Kris Dinarti4, Anggoro Budi Hartopo4,*
    Congenital Heart Disease, DOI:10.32604/chd.2024.054742
    Abstract A particular type of endogenous noncoding RNAs known as circular RNAs (circRNAs) has now become possible biomarkers for several diseases because of their stability and tissue-specific expression patterns. CircRNAs might play a role in various of biological processes. The identification of particular circRNAs dysregulated in pulmonary arterial hypertension (PAH) raises the possibility of these molecules serving as biomarkers for the disease’s early diagnosis and treatment. This review mainly summarizes the role and potential of circRNA as a future biomarker in PAH related to congenital heart disease. This study presented several potential circRNA targets as diagnostic More >
    Graphic Abstract

    The Potential of Circular RNAs as Biomarkers in Pulmonary Arterial Hypertension Related to Congenital Heart Disease

  • Open Access

    REVIEW

    Sodium-Glucose Cotransporter 2 Inhibitors in Adult and Pediatric Congenital Heart Disease: Review of Emerging Data and Future Directions

    William H. Marshall V1,2,*, Lydia K. Wright2
    Congenital Heart Disease, DOI:10.32604/chd.2024.056608
    Abstract Heart failure (HF) is common in patients with congenital heart disease (CHD) and there are limited medical therapies. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are a proven medical therapy in patients with acquired HF, though data are limited in patients with CHD. The aim of this review is to summarize the current evidence for use of SGLT2i in patients with CHD and identify future directions for study. In available publications, SGLT2i in patients with CHD seem to be well tolerated, with similar side effect profile to patients with acquired HF. Improvement in functional capacity and natriuretic More >

  • Open Access

    ARTICLE

    Standardized Management of Acute Pulmonary Hemorrhage after Percutaneous Pulmonary Vein Intervention

    Catalina Vargas-Acevedo1, Gareth J. Morgan1, Rhynn Soderstrom2, Richard Ing3, Nicholas Houska3, Jenny E. Zablah1,*
    Congenital Heart Disease, DOI:10.32604/chd.2024.055121
    Abstract Introduction: Pulmonary hemorrhage (PHm) is a life-threatening complication that can occur after catheter-based interventions in patients with pulmonary vein stenosis (PVS). Inhaled racemic epinephrine (iRE) and tranexamic acid (iTXA) have been used in other conditions, but a standardized approach in PVS has not been described. We aimed to describe the current management of PHm after PVS catheter-based interventions. Methods: We present a retrospective review of episodes of PHm from July 2022 to February 2024. PHm was defined as frank blood suctioned from the endotracheal tube including blood-tinged secretions and >3% decrease in saturations and/or ventilatory… More >

  • Open Access

    LETTER TO THE EDITOR

    Distinguish Rare Dual Left Anterior Descending Artery with Anomalous Origins in Asymptomatic Patients

    Wen Zhang1,2, Ting Wu1,2, Xijian Chen1,3, Hong Luo1,2,*, Yifei Li1,4,*
    Congenital Heart Disease, DOI:10.32604/chd.2024.055178
    Abstract This article has no abstract. More >

  • Open Access

    REVIEW

    The Effects of Laser Therapy in Treating Hypertrophic Scars and Keloids after Median Sternotomy: A Scoping Review

    Laura Schianchi1,*, Fabrizio Vaira2, Massimo Chessa1,3, Serena Francesca Flocco4, Arianna Magon4, Gianluca Conte4, Karina Geraldina Zuniga Olaya5, Giacomo Bortolussi6, Erika Cioffi1, Matteo Riccardo Di Nicola2, Santo Raffaele Mercuri2, Rosario Caruso4,7
    Congenital Heart Disease, DOI:10.32604/chd.2024.053999
    Abstract Background: Hypertrophic scars and keloids, common complications following median sternotomy for cardiac surgery, significantly impact patient quality of life due to their aesthetic and symptomatic burden. Recent advancements in laser therapy have made it a prominent option for managing these complex scars, yet a comprehensive understanding of its efficacy is lacking. The aim of this scoping review is to explore the effects of laser therapy in managing hypertrophic scars and keloids after median sternotomy. Methods: This scoping review analyzed studies up to February 2024 from databases including PubMed, EMBASE, CINAHL, Scopus, Web of Science, and… More >

  • Open Access

    ARTICLE

    Prospective Cohort Research of Aortic Root Dilatation after Surgical Repair in Adults with Tetralogy of Fallot (TRANSIT)

    Hiroki Nagamine1, Masaru Miura1,*, Jun Maeda1, Takumi Nishiki1, Maasa Sato2, Fumie Takechi3, Shigeru Tateno4, Tomoko Ishizu5, Yumi Shiina6, Ken Kato7, Hiroshi Ono8, Hiroyuki Yamagishi9, Koichiro Niwa6
    Congenital Heart Disease, DOI:10.32604/chd.2024.051837
    Abstract Background: Aortic root dilatation occurs in adults with tetralogy of Fallot (TOF) after surgical repair, but the longitudinal changes are unclear. The main research aim is to determine the annual dilatation rate of aorta in adults with repaired TOF. Methods: The present, multicentric, prospective cohort study assessed the rate of aortic diameter change in adults aged 20 years or older with TOF, including pulmonary artery atresia, who underwent surgical repair. Clinical data, focusing on echocardiograms, were collected at three-year intervals from seven hospitals. Results: In total, 104 patients (58 males; median age: 29 years) were enrolled.… More >
    Graphic Abstract

    Prospective Cohort Research of Aortic Root Dilatation after Surgical Repair in Adults with Tetralogy of Fallot (TRANSIT)