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  • Open Access

    EDITORIAL

    Health Systems Strengthening to Tackle the Global Burden of Pediatric and Congenital Heart Disease: A Diagonal Approach

    Dominique Vervoort1,2,3,*, Amy Verstappen3, Sreehari Madhavankutty Nair4, Chong Chin Eu5, Bistra Zheleva3,6
    Congenital Heart Disease, DOI:10.32604/chd.2024.049814
    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    High Prevalence of Anatomical Variations and Anomalies of the Coronary Arteries Detected by CT Angiography in Symptomatic Patients

    Ghazi A. Alshumrani*
    Congenital Heart Disease, DOI:10.32604/chd.2024.049401
    Abstract Objective: Coronary artery anatomical variations and anomalies are an important topic due to their potential clinical manifestations. This study aims to investigate the prevalence of coronary artery anatomical variations and anomalies in symptomatic patients with coronary computed tomography angiography (CCTA). Methods: This is a retrospective study that included all symptomatic patients who had CCTA in a tertiary care hospital in Saudi Arabia during a period of seven years. Results: The total number of included patients was 507 (60% males) with a mean age of 57.4 years. Approximately 41% had luminal stenoses, averaging 49.7%. The total number of patients with coronary… More >

  • Open Access

    REVIEW

    Treatment and Clinical Management of Chronic Thromboembolic Pulmonary Hypertension: An Update of Literature Review

    Yuan Ren1, Yingxian Sun1, Zhiguang Yang2, Yanli Chen1,*
    Congenital Heart Disease, DOI:10.32604/chd.2024.047930
    Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a chronic, progressive, debilitating, and life-threatening complication of pulmonary embolism (PE). Recent technological advances have permitted various treatment options for the treatment of CTEPH, including surgery, angioplasty, and medical treatment, depending on the location and characteristics of lesions. Pulmonary endarterectomy (PEA) is the treatment of choice for CTEPH, as it offers excellent long-term outcomes and a high probability of recovery. Moreover, various medical and interventional therapies are currently being developed for patients with inoperable CTEPH. This review mainly summarizes the current treatment approaches of CTEPH, offering more options for specialist physicians to, thus, better… More >

  • Open Access

    REVIEW

    Machine Learning-Based Intelligent Auscultation Techniques in Congenital Heart Disease: Application and Development

    Yang Wang#, Xun Yang#, Mingtang Ye, Yuhang Zhao, Runsen Chen, Min Da, Zhiqi Wang, Xuming Mo, Jirong Qi*
    Congenital Heart Disease, DOI:10.32604/chd.2024.048314
    Abstract Congenital heart disease (CHD), the most prevalent congenital ailment, has seen advancements in the “dual indicator” screening program. This facilitates the early-stage diagnosis and treatment of children with CHD, subsequently enhancing their survival rates. While cardiac auscultation offers an objective reflection of cardiac abnormalities and function, its evaluation is significantly influenced by personal experience and external factors, rendering it susceptible to misdiagnosis and omission. In recent years, continuous progress in artificial intelligence (AI) has enabled the digital acquisition, storage, and analysis of heart sound signals, paving the way for intelligent CHD auscultation-assisted diagnostic technology. Although there has been a surge… More >
    Graphic Abstract

    Machine Learning-Based Intelligent Auscultation Techniques in Congenital Heart Disease: Application and Development

  • Open Access

    ARTICLE

    Failure to Rescue as a Quality Metric in Congenital Heart Surgeries in a High-Complexity Service Provider Institution Located in a Middle-Income Country

    Gustavo Cruz1,*, Santiago Pedroza2, Juan F. Vélez3, Jessica Largo2, Juan F. Tejada4, Jorge H. Mejía-Mantilla5
    Congenital Heart Disease, DOI:10.32604/chd.2024.044244
    Abstract Background: Failure to rescue has been an effective quality metric in congenital heart surgery. Conversely, morbidity and mortality depend greatly on non-modifiable individual factors and have a weak correlation with better-quality performance. We aim to measure the complications, mortality, and risk factors in pediatric patients undergoing congenital heart surgery in a high-complexity institution located in a middle-income country and compare it with other institutions that have conducted a similar study. Methods: A retrospective observational study was conducted in a high-complexity service provider institution, in Cali, Colombia. All pediatric patients undergoing any congenital heart surgery between 2019 and 2022 were included.… More >

  • Open Access

    CASE REPORT

    Stubborn Hypoxia in Neonates with D-Transposition of the Great Arteries after Arterial Switch Operation: Central Sleep Apnea as the Cause and Potential Indicator of Brain Immaturity

    Camden L. Hebson1,*, Kyle Bliton2, Amr Y. Hammouda1, Kaitlyn Barr3, W. Hampton Gray4, Mohini Gunnett2, Waldemar F. Carlo1
    Congenital Heart Disease, DOI:10.32604/chd.2024.048871
    Abstract D-transposition of the great arteries (d-TGA) is surgically repaired with the arterial switch operation (ASO) with excellent results, however short and long-term morbidities still develop including neurocognitive delay. Clinically significant central sleep apnea is uncommon in non-premature infants, but when present indicates immature autonomic control of respiration likely due to a neurologic disorder. We report the unanticipated finding of central sleep apnea in four-term neonates with d-TGA after uncomplicated ASO, with the short-term complication of delayed hospital discharge and long-term concerns regarding this early marker of brain immaturity and its hindrance to normal development. Within this report, we will review… More >