Open Access
ARTICLE
Ylenia Bartolacelli*, Giulia Bragantini
Congenital Heart Disease, Vol.15, No.2, pp. 59-68, 2020, DOI:10.32604/CHD.2020.011448
Abstract Objective: The objective of this study was to assess left ventricle (LV)
function and remodeling by three-dimensional echocardiography (3DE) in patients
who underwent arterial switch procedure (ASO) for transposition of great arteries
(TGA) in long-term follow-up. Methods and Results: We studied 54
asymptomatic patients (39 male) who have undergone single-stage ASO for TGA,
aged 13.7 ± 4.7 years, with a normal LV ejection fraction (EF), compared to
healthy peers. We evaluated LV volume and function in asymptomatic patients
with normal ejection fraction by 3DE. All patients had normal EF, measured by
modified Simpson’s method (mean 60.9 ± 3.5%) and by… More >
Open Access
ARTICLE
Liesbeth van Dessel1, Béatrice Santens2, Els Troost2, Pieter De Meester2,3, Leen Roggen2, Filip Rega3,4, Bart Meyns3,4, Bjorn Cools5, Marc Gewillig5, Philip Moons6,7,8, Lukas Meier9, Werner Budts2,3, Alexander Van De Bruaene2,3,*
Congenital Heart Disease, Vol.15, No.2, pp. 69-78, 2020, DOI:10.32604/CHD.2020.011512
Abstract Background: Left-to-right shunt in sinus venosus septal defect (SVSD)
may affect resistive (pulmonary vascular resistance–PVR) and elastic (pulmonary
artery compliance-PAC) pulmonary artery properties. This study aimed at evaluating
(1) impact of age, (2) pulmonary hemodynamics, and (3) outcome in a large cohort
of SVSD patients. Methods: This study included 136 patients with SVSD (median
age at diagnosis 14 (IQR 5–48) years, 47% male) of which 87 underwent
catheterization. Pressures were measured and cardiac output was evaluated using the
Fick principle at diagnosis. PVR, PAC and their product (RC time) were calculated.
Results: Surgical repair was performed in 128 (94%) at… More >
Open Access
ARTICLE
Amira Nour1,*, Heba Kamel1, Yasmeen Abdelrazik1, Khaled Shams2, Noha Gamal3, Safaa Huessin4, Alaa Roushdy1, Maiy El Sayed1
Congenital Heart Disease, Vol.15, No.2, pp. 79-87, 2020, DOI:10.32604/CHD.2020.011249
Abstract Background: Transcatheter closure of secudum atrial septal defect (ASD)
has gained wide acceptance since its introduction more than 3 decades ago. Safety
and efficacy of the procedure in everyday practice needs continuous update.
Objective: The aim of the study is to determine the incidence of complications and
identify everyday management protocols. Methods: This is a prospective
nonrandomized study including all the patients with Secundum ASD or fenestrated
IAS referred to two different congenital heart diseases centers in Ain Shams
university and sohag university in Egypt over 2 years with an indication for closure
according to American and European guidelines. A… More >
Open Access
ARTICLE
Karina V. Bunting1,2,*, Francesco Formisano3, Jennifer Green1, Richard P. Steeds1,2, Lucy Hudsmith1, Paul Clift1,2
Congenital Heart Disease, Vol.15, No.2, pp. 89-100, 2020, DOI:10.32604/CHD.2020.011376
Abstract Objective: To determine the accuracy of assessing univentricular
function in adult Fontan patients using three-dimensional (3D) volumetric
echocardiography. Design: A prospective observational study in an adult Fontan
patient cohort. Setting: University Hospitals Birmingham, NHS Foundation
Trust. Patients: 26 patients were enrolled in the study all aged over 18 years,
possessing the Fontan anatomy, with no contraindications to Cardiac Magnetic
Resonance (CMR) imaging and in sinus rhythm. Intervention: All patients
underwent transthoracic echocardiography using a Philips EPIQ 7 and X5-1
transducer. End diastolic volume (EDV), end systolic volume (ESV), stroke
volume (SV) and ejection fraction (EF) were obtained using two dimensional… More >
Open Access
ARTICLE
Shivani M. Bhatt1,*, Michael L. O’Byrne2, Michael McBride2, Stephen M. Paridon2, Elizabeth Goldmuntz2, Laura Mercer-Rosa2
Congenital Heart Disease, Vol.15, No.2, pp. 101-115, 2020, DOI:10.32604/CHD.2020.011287
Abstract Objective: The determinants of exercise capacity in repaired tetralogy of
Fallot (rTOF) are multifactorial and remain incompletely understood. This study
sought to evaluate the association of chronotropic response with exercise parameters
and investigate the determinants of heart rate reserve (HRR) in a cohort of children
and adolescents with rTOF. Design: We retrospectively analyzed patients with
rTOF, age 8–18 years, who underwent cardiac magnetic resonance (CMR) and
cardiopulmonary exercise test (CPET) for research purposes. Linear regression
models were performed to test associations among clinical, CMR and CPET
parameters. Outcomes included percent-predicted maximum VO2 (%mVO2) and
HRR. Results: A total of 148… More >
Open Access
ARTICLE
Coralie Katharina Dicks1, Gerhard-Paul Diller1, Kristina Wasmer2, Paul C. Helm3,4, Ulrike M. M. Bauer3,4, Helmut Baumgartner1, Stefan Orwat1,#, Alicia Jeanette Fischer1,#,*
Congenital Heart Disease, Vol.15, No.2, pp. 117-125, 2020, DOI:10.32604/CHD.2020.011520
Abstract Background: Sudden cardiac death is a leading cause of death in
patients with congenital heart disease (CHD). Risk stratification for implantable
cardioverter defibrillators (ICD) remains difficult due to limited data about use
and outcome of device therapy in CHD patients in larger community-based
cohorts. Methods and results: Out of a dataset with more than 50,000 patients
registered at the German National Register for Congenital Heart Defects, 109
patients (median age 35.5; IQR 23.75–46.00), 68 (62%) male) with an ICD were
identified and were retrospectively analyzed. Although the number of
implantations increased steadily throughout the investigated time interval from
2001 to… More >
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