Home / Journals / CHD / Vol.18, No.2, 2023
  • Open AccessOpen Access

    REVIEW

    The Prevalence of Congenital Heart Disease among School-Age Children in China: A Meta-Analysis and Systematic Review

    Shuqin Zhang1,#, Bin Zhang2,#, Jianying Wu3, Jin Luo1, Haomin Shi1, Jirong Qi3,4,*, Huilian Yang1,5,*
    Congenital Heart Disease, Vol.18, No.2, pp. 127-150, 2023, DOI:10.32604/chd.2023.025616
    Abstract Objectives: To estimate the prevalence of Congenital Heart Disease (CHD) in school-age children, to identify the extent to which altitude affects the prevalence of the disease, and to examine trends in prevalence over time in China. Methods: Seven databases were systematically searched and last retrieved on September 10, 2021 for all studies reporting the prevalence of CHD in children after 1970 in China, which were then divided into high and low altitude regions based on 2500 meters above sea level. The random-effected model was used to combine prevalence data and subgroups analysis. The baseline data of all cases and individuals… More >

    Graphic Abstract

    The Prevalence of Congenital Heart Disease among School-Age Children in China: A Meta-Analysis and Systematic Review

  • Open AccessOpen Access

    ARTICLE

    Cardiac Surgery with Cardiopulmonary Bypass in Low-Weight or Preterm Neonates: A Retrospective Study Analyzing Early Outcome

    Alain J. Poncelet1,*, Maureen Peers de Nieuwburgh2, Stéphane Moniotte2, Geoffroy de Beco1, Karlien Carbonez2, Jean E. Rubay1, Thierry Detaille3, Laurent Houtekie3, Mona Momeni4
    Congenital Heart Disease, Vol.18, No.2, pp. 151-168, 2023, DOI:10.32604/chd.2023.022636
    Abstract Background: Most outcome studies in congenital cardiac surgery for “low weight” neonates include patients undergoing surgery without cardiopulmonary bypass (CPB). The primary objective of our study was to identify risk factors for in-hospital mortality in neonates weighing less than 3 Kg and undergoing surgery with CPB. In addition, we compared the effect of early surgery with CPB (before 37W-gestational age (GA)) for congenital heart disease to delayed surgery until a corrected GA of 37 weeks in an attempt to promote weight gain. Methods: Retrospective single-center study including all patients operated between 1997 and 2017. Uni- and multivariable analysis were used… More >

  • Open AccessOpen Access

    ARTICLE

    Outcomes of Transcatheter Closure in Outlet-Type Ventricular Septal Defect after 1 Year

    Supaporn Roymanee1,*, Nantawan Su-angka1,2, Worakan Promphan2,3,*, Kanjarut Wongwaitaweewong1, Jirayut Jarutach1, Rujira Buntharikpornpun1, Pimpak Prachasilchai2,3
    Congenital Heart Disease, Vol.18, No.2, pp. 169-181, 2023, DOI:10.32604/chd.2023.021238
    Abstract Background: Ventricular septal defect (VSD) is the most common congenital heart disease. Transcatheter VSD closure is an effective treatment for patients with muscular and perimembranous VSD. However, there is a limit data for outlet VSD, especially impact to the aortic valve leaflet after transcatheter closure. This study aims to assess the outcomes of transcatheter closure of the outlet-type ventricular septal defect (OVSD) after 1 postoperative year. Methods: A retrospective study was performed including 50 patients who underwent transcatheter (n = 25) and surgical (n = 25) OVSD closure during the exact time frame at two medical centres. Results: The median age and body weight… More >

    Graphic Abstract

    Outcomes of Transcatheter Closure in Outlet-Type Ventricular Septal Defect after 1 Year

  • Open AccessOpen Access

    ARTICLE

    Effectiveness and Safety of Transcatheter Closure of Various Ventricular Septal Defects Using Second-Generation Amplatzer Duct Occluders

    Jianming Wang, Qiguang Wang*, Xiaotang Sheng, Jingsong Geng, Jiawang Xiao, Xianyang Zhu*
    Congenital Heart Disease, Vol.18, No.2, pp. 183-195, 2023, DOI:10.32604/chd.2022.021855
    Abstract Objective: This study was designed to determine the long-term safety and efficacy of using the Amplatzer Duct Occluder II (ADO II) for the closure of various ventricular septal defects (VSDs). Methods: From January 2011 to December 2019, selected VSD patients were treated through transcatheter intervention using ADO II occluders. The closure results and complications from 188 patients, involving 167 perimembranous ventricular septal defects (pmVSDs), 9 intracristal VSDs, 11 post surgery residual shunts and 1 post closure residual shunt with the mean outlet diameter3.1 ± 0.8 mm under angiography, were enrolled in this study. Results: The success rate was 98.9% for… More >

  • Open AccessOpen Access

    ARTICLE

    Quality of Life in Congenital Heart Disease Patients According to Their Anatomical and Physiological Classification

    Efrén Martínez-Quintana1,2,*, Hiurma Estupiñán-León2, Ana Beatriz Rojas-Brito2, Liuva Déniz-Déniz2, Alejandro Barreto-Martín2, Fayna Rodríguez-González3
    Congenital Heart Disease, Vol.18, No.2, pp. 197-206, 2023, DOI:10.32604/CHD.2021.013308
    Abstract Background: Living well is as important as living longer. The objective of this study is to assess quality of life (QoL) in congenital heart disease (CHD) according to current AHA/ACC anatomical and physiological classifi- cation. Methods: Cross-sectional study examining the World Health Organization QoL Bref questionnaire (WHOQoL-Bref) in consecutive outpatient CHD patients from a single unit. Results: 191 CHD patients were studied. Median age was 28 ± 13 years and 59% were male. 44 (23%), 115 (60%) and 33 (17%) CHD patients showed mild, moderate and great anatomical defects respectively while 69 (36%) patients were in physiological Stage A, 27… More >

  • Open AccessOpen Access

    CASE REPORT

    Giant-Size Main Pulmonary Artery Aneurysm in an Adult Patient with Ebstein Anomaly and Dextrocardia

    Kristina Krzelj1,#,*, Irena Ivanac Vranesic2,#, Kristina Maric Besic2, Zeljko Duric1, Darko Anic1
    Congenital Heart Disease, Vol.18, No.2, pp. 207-212, 2023, DOI:10.32604/chd.2023.027453
    (This article belongs to this Special Issue: Nightmare Case Reports in Congenital Heart Disease)
    Abstract Main pulmonary artery aneurysms are rare, mostly asymptomatic and discovered accidentally. The main pulmonary artery aneurysms may be idiopathic or secondary to underlying diseases such as pulmonary hypertension, Behcet’s disease, connective tissue disorders, congenital heart disease, vasculitis, syphilis, tuberculosis and endocarditis. There are some indices that dextrocardia is associated with anomalies of the pulmonary arteries and pulmonary valve. A rare occurrence of main pulmonary artery aneurysms results in a lack of recommendations, so the remaining challenges are whether main pulmonary artery aneurysms should be treated, how, and when. The decision on surgical intervention or conservative treatment of the main pulmonary… More >

    Graphic Abstract

    Giant-Size Main Pulmonary Artery Aneurysm in an Adult Patient with Ebstein Anomaly and Dextrocardia

  • Open AccessOpen Access

    CASE REPORT

    Compound Heterozygous PLD1 Variants in Right-Sided Heart Malformations

    Cherith Somerville1,2, Kelsey Kalbfleisch1,2, Roozbeh Manshaei1,2, Qiliang Ding1,2, John B.A. Okello1,2,3, Rachel Silver4, David Chitayat2,4, Varsha Thakur5, Olivier Villemain5,6,7, Rebekah Jobling1,2,8,*
    Congenital Heart Disease, Vol.18, No.2, pp. 213-218, 2023, DOI:10.32604/chd.2023.023042
    Abstract We report a three-year-old male child who presented with congenital valvular defects, right ventricular malformation, and initial developmental delay. Genome sequencing showed rare deleterious biallelic missense variants in PLD1. In his parents’ second pregnancy, echocardiogram at 13 weeks gestation revealed right-sided cardiac malformations resembling the clinical presentation of the family’s first child. Targeted DNA analysis showed that the fetus carried the same biallelic PLD1 variants as their older sibling. This case helps to further delineate the clinical spectrum of PLD1-related defects and highlights the value of both genome sequencing in congenital heart disease and early fetal echocardiography to establish phenotype. More >

  • Open AccessOpen Access

    ARTICLE

    Outcomes of Self-Expanding Transcatheter Pulmonary Valves: Extended Follow-Up of a Prospective Trial

    Jingnan Zhang1, Junyi Wan1, Yihang Li2, Yu Han2, Jiahua Pan3, Fang Fang1, Shiliang Jiang4, Xiangbin Pan1, Gejun Zhang1,*
    Congenital Heart Disease, Vol.18, No.2, pp. 219-234, 2023, DOI:10.32604/chd.2023.027562
    Abstract Background: The Venus-P valve was the first self-expanding valve used world-wide for transcatheter pulmonary valve replacement (TPVR) in patients with severe pulmonary regurgitation (PR). We intended to report the extended follow-up results from the prospective trial (No. NCT02590679). Methods: A total of 38 patients with severe PR (mean age 24.2 ± 13.2) were included. Follow-up data were obtained after implanted at 1, 6, and 12 months and yearly after. The frame geometry was assessed on post-implant computer tomography (CT) scanning by calculating the non-circularity [circularity ratio (minimum diameter/maximum diameter) < 0.9] and under-expansion [expansion ratio (derived external valve area/nominal external valve area)… More >

    Graphic Abstract

    Outcomes of Self-Expanding Transcatheter Pulmonary Valves: Extended Follow-Up of a Prospective Trial

  • Open AccessOpen Access

    ARTICLE

    Effects of General Anesthesia on the Results of Cardiac Catheterization in Pediatric Patients with Ventricular Septal Defect

    Kiyotaka Go1,2, Taichi Kato2,*, Machiko Kito1, Yoshihito Morimoto1,2, Satoru Kawai1, Hidenori Yamamoto2, Yoshie Fukasawa2, Kazushi Yasuda1
    Congenital Heart Disease, Vol.18, No.2, pp. 235-243, 2023, DOI:10.32604/chd.2023.027590
    Abstract Background: There is no gold standard sedation method for pediatric cardiac catheterization. In congenital heart diseases with intracardiac shunts, hemodynamic parameters are prone to change depending on the ventilation conditions and anesthetics, although few studies have examined these effects. The purpose of this study was to investigate the effects of two different sedation methods on the hemodynamic parameters. Methods: This study retrospectively evaluated consecutive patients with ventricular septal defect (VSD) below 1 year of age who underwent cardiac catheterization at Aichi Children’s Health and Medical Center, who were divided into age- and VSD diameter-matched general anesthesia (GA) and monitored anesthesia… More >

  • Open AccessOpen Access

    REVIEW

    Transcatheter Closure vs. Surgical Ligation in Preterm Infants with Patent Ductus Arteriosus: A Systematic Review and Meta-Analysis

    Rohan Suresh Daniel1,2, Georgia K. Schmidt1,2, Hayato Nakanishi1,2, Karen Smayra1,2, Mariah N. Mascara1,2, Dilip K. Vankayalapati1,2, Reem H. Matar1,2,3, Christian A. Than1,2,4, George Shiakos5, Ioannis Tzanavaros2,5,*
    Congenital Heart Disease, Vol.18, No.2, pp. 245-265, 2023, DOI:10.32604/chd.2023.027596
    Abstract Background: Persistent patent ductus arteriosus (pPDA) is a common condition in preterm infants. This meta-analysis aimed to assess the safety and efficacy of transcatheter closure (TC) when compared to surgical ligation (SL) in preterm infants with pPDA. Methods: A literature search of Ovid Cochrane Library, Medline, Embase, Epub, Scopus, PMC Preprints, and was conducted from inception to May 06, 2022. Eligible studies reported infants diagnosed with pPDA born at ≤2000 g birth weight or at ≤37 weeks’ who underwent TC or SL as treatment. This review was registered in PROSPERO (CRD42022325944). Results: From 97 studies screened, 8 studies met the… More >

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