Special Issues
Table of Content

Advances in Cancer Immunotherapy

Submission Deadline: 30 December 2025 View: 956 Submit to Special Issue

Guest Editors

Wenxue Ma, University of California, San Diego, USA. E-mail: wma@health.ucsd.edu
Manoj Kumar Kashyap, Amity University Haryana, India. E-mail: mkkashyap@ggn.amity.edu
Lingeng Lu, Yale University, USA. E-mail: lingeng.lu@yale.edu


Summary

Cancer immunotherapy has revolutionized cancer treatment by harnessing the power of the immune system to target and eradicate cancer cells. This special issue aims to provide an overview of the recent advances in cancer immunotherapy.

 

Potential topics include but are not limited to the following:

1. Immunotherapy for solid tumors

2. Biomarkers for immunotherapy response

3. Immune-related adverse events

4. Mechanisms of immune escape

 

Immunotherapy for solid tumors: This section will discuss the latest updates in immunotherapy for solid tumors, including cytokines, cancer vaccines, immune checkpoint inhibitors, monoclonal antibodies, adoptive cell therapy, etc.

 

Biomarkers for immunotherapy response: This section will highlight the latest developments in biomarkers for predicting response to immunotherapy and monitoring treatment efficacy.

 

Immune-related adverse events: This section will cover the management of immune-related adverse events associated with cancer immunotherapy.

 

Mechanisms of immune escape: This section will discuss the mechanisms by which cancer cells evade the immune system and how to overcome these barriers to enhance the effectiveness of cancer immunotherapy.

 

This special issue will provide a comprehensive overview of the recent advances in cancer immunotherapy, highlighting the challenges and opportunities for future research in this field.


Keywords

Immunotherapy, solid tumor, immune checkpoint inhibitors, adoptive cell therapy, and cancer vaccines; Immune-related adverse events, immune escape, immune response, biomarkers

Published Papers


  • Open Access

    ARTICLE

    ZMIZ2/MCM3 Axis Participates in Triple-Negative Breast Cancer Progression

    Xiaopan Zou, Meiyang Sun, Xin Jiang, Jingze Yu, Xiaomeng Li, Bingyu Nie
    Oncology Research, DOI:10.32604/or.2025.066662
    (This article belongs to the Special Issue: Advances in Cancer Immunotherapy)
    Abstract Objective: Triple-negative breast cancer (TNBC) is highly aggressive and lacks an effective targeted therapy. This study aimed to elucidate the functions and possible mechanisms of action of zinc finger miz-type containing 2 (ZMIZ2) and minichromosome maintenance complex component 3 (MCM3) in TNBC progression. Methods: The relationship between ZMIZ2 expression and clinical characteristics of TNBC was investigated. In vitro and in vivo experiments were performed to investigate the role of ZMIZ2 dysregulation in TNBC cell malignant behaviors. The regulatory relationship between ZMIZ2 and MCM3 was also explored. Transcriptome sequencing was performed to elucidate possible mechanisms underlying the ZMIZ2/MCM3… More >

  • Open Access

    ARTICLE

    Application Value and Research Frontiers of Immunotherapy in Glioblastoma: A Bibliometric and Visualized Analysis

    Kun Deng, Jianliang Huang, Danyang Li, Wei Gao, Minghua Wu, Mingsheng Lei
    Oncology Research, DOI:10.32604/or.2025.069442
    (This article belongs to the Special Issue: Advances in Cancer Immunotherapy)
    Abstract Background: Glioblastoma (GBM) prognosis has seen little improvement over the past two decades. While immunotherapy has revolutionized cancer treatment, its impact on GBM remains limited. To characterize the evolving research landscape and identify future directions in GBM immunotherapy, we conducted a comprehensive bibliometric review. Methods: All literature related to immunotherapy in GBM from 1999 to 2024 was collected from the Web of Science Core Collection. CtieSpace and VOSviewer were used to conduct bibliometric analysis and visualize the data. Results: Bibliometric analysis identified 5038 publications authored by 23,335 researchers from 4699 institutions across 96 countries/regions, published in… More >

  • Open Access

    REVIEW

    Opportunities and challenges of CD47-targeted therapy in cancer immunotherapy

    QIUQIANG CHEN, XUEJUN GUO, WENXUE MA
    Oncology Research, Vol.32, No.1, pp. 49-60, 2024, DOI:10.32604/or.2023.042383
    (This article belongs to the Special Issue: Advances in Cancer Immunotherapy)
    Abstract Cancer immunotherapy has emerged as a promising strategy for the treatment of cancer, with the tumor microenvironment (TME) playing a pivotal role in modulating the immune response. CD47, a cell surface protein, has been identified as a crucial regulator of the TME and a potential therapeutic target for cancer therapy. However, the precise functions and implications of CD47 in the TME during immunotherapy for cancer patients remain incompletely understood. This comprehensive review aims to provide an overview of CD47’s multifaced role in TME regulation and immune evasion, elucidating its impact on various types of immunotherapy… More >

    Graphic Abstract

    Opportunities and challenges of CD47-targeted therapy in cancer immunotherapy

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