Guest Editors
Dr. Victor Loschenov
Email: loschenov@nsc.gpi.ru
Affiliation: Institute of Engineering Physics for Biomedicine, National Research Nuclear University MEPHI, Moscow, 115409, Russia
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Research Interests: laser spectroscopy in medicine, photodynamic therapy, fluorescence diagnostics, laser biospectroscopy, nanostructures for biomedicine, fluorescence imaging
Summary
One of the most significant challenges in oncology is determining the impact of the microenvironment on tumor development and identifying methods to regulate this process. Methods based on spectroscopic measurements of fluorescence and oxygenation allow for noninvasive identification of key characteristics of oncogenesis. Photodynamic effects on tumor cells and tumor-associated immune cells open the possibility of their reprogramming. Oxygenation of the tumor itself, the matrix, and the microvascular system can also be measured using time-resolved spectroscopy, opening up new possibilities for guiding various cancer treatments. This special issue invites papers related to the latest advances in biophotonics, laser spectroscopy, and nanomedicine aimed at the diagnosis, phenotyping, and treatment of cancer, with a special emphasis on methods for assessing the metabolic state of tissues and investigating the mechanisms of action of phototherapy, namely photodynamic therapy (PDT), photothermal therapy (PTT), and photodynamic inactivation (PDI).
Grammarly 100
Keywords
tumor microenvironment, reprogramming, cellular respiration, phototheranostics
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