Home / Journals / CMES / Vol.98, No.1, 2014
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  • Open Access

    EDITORIAL

    Preface

    Franck Vernerey, Shaofan Li
    CMES-Computer Modeling in Engineering & Sciences, Vol.98, No.1, 2014
    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Large Deformation Dynamic Three-Dimensional Coupled Finite Element Analysis of Soft Biological Tissues Treated as Biphasic Porous Media

    R.A. Regueiro1,2, B. Zhang2, S.L. Wozniak3
    CMES-Computer Modeling in Engineering & Sciences, Vol.98, No.1, pp. 1-39, 2014, DOI:10.3970/cmes.2014.098.001
    Abstract The paper presents three-dimensional, large deformation, coupled finite element analysis (FEA) of dynamic loading on soft biological tissues treated as biphasic (solid-fluid) porous media. An overview is presented of the biphasic solidfluid mixture theory at finite strain, including inertia terms. The solid skeleton is modeled as an isotropic, compressible, hyperelastic material. FEA simulations include: (1) compressive uniaxial strain loading on a column of lung parenchyma with either pore air or water fluid, (2) out-of-plane pressure loading on a thin slab of lung parenchyma with either pore air or water fluid, and (3) pressure loading on a 1/8th symmetry vertebral disc… More >

  • Open Access

    ARTICLE

    Simulations of Blood Drop Spreading and Impact for Bloodstain Pattern Analysis

    Chu Wang, Lucy T. Zhang1
    CMES-Computer Modeling in Engineering & Sciences, Vol.98, No.1, pp. 41-67, 2014, DOI:10.3970/cmes.2014.098.041
    Abstract Bloodstain pattern analysis (BPA) in forensic science is an important tool to solve crime scenes. The complex dynamic behavior of blood drops poses great challenges for accurate fluid dynamic simulations. In this paper, we specifically focus on simulations of blood drop spreading and impact, which may involve contact line hysteresis and spattering of drops as they interact with solid surfaces. Here, we set up a numerical framework that combines (1) the connectivity-free front tracking (CFFT) method for modeling multiphase (air and liquid) flows and (2) a dynamic contact line model for modeling fluid-solid contact line. Both components are necessary in… More >

  • Open Access

    ARTICLE

    A Meshfree Method For Mechanics and Conformational Change of Proteins and Their Assemblies

    Ankush Aggarwal1, Jiun-Shyan Chen2, William S. Klug3
    CMES-Computer Modeling in Engineering & Sciences, Vol.98, No.1, pp. 69-99, 2014, DOI:10.3970/cmes.2014.098.069
    Abstract Mechanical properties of proteins play an important role in their biological function. For example, microtubules carry large loads to transport organelles inside the cell, and virus shells undergo changes in shape and mechanical properties during maturation which affect their infectivity. Various theoretical models including continuum elasticity have been applied to study these structural properties, and a significant success has been achieved. But, the previous frameworks lack a connection between the atomic and continuum descriptions. Here this is accomplished through the development of a meshfree framework based on reproducing kernel shape functions for the large deformation mechanics of protein structures. The… More >

  • Open Access

    ARTICLE

    Particle-Based Moving Interface Method for The Study of the Interaction Between Soft Colloid Particles and Immersed Fibrous Network

    Louis C. Foucard1, John Pellegrino1, Franck J. Vernerey1,2
    CMES-Computer Modeling in Engineering & Sciences, Vol.98, No.1, pp. 101-127, 2014, DOI:10.3970/cmes.2014.098.101
    Abstract Many colloidal-sized particles encountered in biological and membranebased separation applications can be characterized as soft vesicles such as cells, yeast, viruses and surfactant micelles. The deformation of these vesicles is expected to critically affect permeation by accommodating pore shapes and sizes or enhancing the adhesion with a pore surface. Numerical and theoretical modelings will be critical to fully understand these processes and thus design novel filtration membranes that target, not only size, but deformability as a selection criterion. The present paper therefore introduces a multiscale strategy that enables the determination of the permeability of a fibrous network with respect to… More >

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