MicroCT/Micromechanics-Based Finite Element Models and Quasi-Static Unloading Tests Deliver Consistent Values for Young's Modulus of Rapid-Prototyped Polymer-Ceramic Tissue Engineering Scaffold
K.W. Luczynski1, A. Dejaco1, O. Lahayne1, J. Jaroszewicz2, W.Swieszkowski2, C. Hellmich1
CMES-Computer Modeling in Engineering & Sciences, Vol.87, No.6, pp. 505-529, 2012, DOI:10.3970/cmes.2012.087.505
Abstract A 71 volume-% macroporous tissue engineering scaffold made of poly-l-lactide (PLLA) with 10 mass-% of pseudo-spherical tri-calcium phosphate (TCP) inclusions (exhibiting diameters in the range of several nanometers) was microCT-scanned. The corresponding stack of images was converted into regular Finite Element (FE) models consisting of around 100,000 to 1,000,000 finite elements. Therefore, the attenuation-related, voxel-specific grey values were converted into TCP-contents, and the latter, together with nanoindentation tests,entered a homogenization scheme of the Mori-Tanaka type, as to deliver voxel-specific (and hence, finite element-specific) elastic properties. These FE models were uniaxially loaded, giving access to the… More >
Login
Register
Submit a Paper
Propose a Special lssue