Guest Editors
Dr. Ziheng Wang
Email: zihengwang@um.edu.mo
Affiliation: MOE Frontier Science Centre for Precision Oncology, University of Macau, Macau SAR, 999078, China
Homepage:
Research Interests: Bioinformatics, Machine learning, Sequencing
Prof. Lin Zhang
Email: Lin.Zhang2@monash.edu
Affiliation: The School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3000, Australia
Homepage:
Research Interests: Health Behavior Change, Machine Learning, Natural Product Analysis, Digital Dietary Interventions, Cancer Screening
Prof. Peng Luo
Email: luopeng@smu.edu.cn
Affiliation: Department of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China
Homepage:
Research Interests: Immunotherapy, Tumor Microenvironment, Machine Learning
Summary
Biomarker discovery in oncology plays a crucial role in advancing personalized medicine, offering tailored therapeutic strategies that are more effective for individual patients. With the growing understanding of cancer biology and genetics, researchers are identifying specific molecular signatures associated with tumor characteristics, patient responses, and disease progression. This ongoing research aims to uncover biomarkers that can predict treatment outcomes, enhance patient stratification, and improve overall cancer management.
Emerging technologies, including high-throughput sequencing, mass spectrometry, and advanced imaging techniques, are being leveraged to discover novel biomarkers in various cancer types. Biomarkers such as circulating tumor DNA (ctDNA), protein markers, and specific genetic alterations have shown promise in guiding targeted therapies and immunotherapies. These advancements enable oncologists to select the most appropriate treatment plans based on the unique molecular profiles of tumors.
Moreover, biomarker-driven clinical trials are increasingly focusing on patient subgroups, thereby optimizing therapeutic efficacy and minimizing adverse effects. The integration of biomarkers into clinical practice not only enhances treatment decision-making but also contributes to the development of new therapeutic agents. Ultimately, the pursuit of novel biomarkers in oncology is vital for realizing the full potential of personalized medicine, leading to improved patient outcomes and survival rates.
Keywords
Biomarker Discovery, Oncology, Personalized Medicine, Tailored Therapeutic Strategies
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