Guest Editor(s)
Prof. Yong Teng
Email: yong.teng@emory.edu
Affiliation: Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA
Homepage:
Research Interests: metastasis; molecular pathway; cancer models; metabolism; tumor microenvironment; drug screening and development
Prof. Nabil F Saba
Email: nfsaba@emory.edu
Affiliation: Department of Hematology and Medical Oncology, Emory University, Atlanta, GA 30322, USA
Homepage:
Research Interests: Head and Neck Cancer, Clinical and Translational Research; Immunotherapy, Novel Systemic therapy approaches
Summary
The tumor microenvironment (TME) plays a pivotal role in the initiation, progression, and therapeutic resistance of cancers. This dynamic ecosystem, comprising cancer cells, stromal cells, immune cells, and extracellular matrix components, creates a complex network of interactions that influence tumor behavior. Understanding the mechanisms underlying TME dynamics is essential for developing innovative therapeutic strategies and improving patient outcomes.
This special issue aims to explore the latest advances in TME research, including its molecular and cellular components, role in immune evasion, and influence on therapeutic resistance. Submissions are invited on topics such as TME-targeted therapies, the development of predictive biomarkers, and innovative models for studying the TME. Both experimental and clinical studies, as well as comprehensive reviews, are welcome.
We believe this special issue will provide a platform to advance our understanding of the TME and foster the development of novel interventions in cancer therapy.
Keywords
Tumor Microenvironment (TME), Cancer Immunotherapy, Tumor-Immune Interactions, Extracellular Matrix Remodeling, Angiogenesis in Cancer, Therapeutic Resistance, Tumor-Associated Stromal Cells, Biomarkers in TME
Published Papers
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