Guest Editors
Dr. Elham Saberian
Email: esaberia@purdue.edu
Affiliation: 1. Department of Mechanical Engineering, Purdue University, West Lafayette, USA
2. Clinic of Dentistry and Maxillofacial Surgery, Kosice, Slovakia
Homepage: https://loop.frontiersin.org/people/2920634/overview
Research Interests: cancer therapy, biomaterials, nanomedicine, oral cancer therapy, drug delivery systems, tissue engineering, regenerative medicine, hydrogel systems, nanoparticles for cancer treatment, scaffold-based therapeutics, stem cell-based therapies

Prof. Dr. David K. Mills
Email: dkmills@latech.edu
Affiliation: Department of Biomedical Engineering, Tulane University, New Orleans, United States
Homepage:
Research Interests: cancer therapy, biomaterials, tissue engineering, regenerative medicine, drug delivery, nanomedicine

Summary
Nanomaterials and advanced biomaterials have emerged as transformative tools in cancer therapy, offering innovative solutions for targeted drug delivery, improved therapeutic efficacy, and reduced systemic toxicity. Recent advances in nanotechnology, hydrogel systems, bioengineered scaffolds, and nano-enabled delivery platforms have enabled precise control over drug release, enhanced tumor targeting, and improved therapeutic outcomes. These technologies play a critical role in addressing the limitations of conventional cancer treatments, including poor targeting efficiency, systemic side effects, and limited regenerative capacity.
In addition to cancer treatment, biomaterial-based platforms contribute significantly to tissue regeneration and post-treatment recovery. Nanoparticles, polymeric biomaterials, nanocomposite scaffolds, and bioengineered systems are increasingly used to support tissue repair, promote cell growth, and enhance regeneration in cancer-affected tissues.
This Special Issue aims to present recent advances in nanomaterials, biomaterials, and drug delivery systems for cancer therapy and regenerative medicine. Topics of interest include nanoparticle-based therapeutics, hydrogel-based drug delivery, scaffold-mediated therapy, nanotechnology-enabled cancer treatments, regenerative biomaterials, stem cell-based therapeutic strategies, and translational applications. This Special Issue will provide a comprehensive platform for interdisciplinary research at the intersection of oncology, nanomedicine, and regenerative medicine.
Keywords
nanomaterials, biomaterials, cancer therapy, drug delivery, nanoparticles, nanomedicine, hydrogels, scaffolds, regenerative medicine, tissue engineering, oral cancer, targeted therapy