Guest Editors
Prof. Maria Beatrice Morelli
Email: mariabeatrice.morelli@unicam.it
Affiliation: School of Pharmacy, University of Camerino, 62032 Camerino, Italy
Homepage:
Research Interests: cancer biology, liquid biopsy, personalized therapy, ion channels, vanilloid receptor, cannabinoids, natural compound, chemoresistance
Prof. Alexander Shtil
Email: shtilaa@yahoo.com
Affiliation: Blokhin National Medical Research Center of Oncology, 24 Kashirskoye Shosse, 115522 Moscow, Russia
Homepage:
Research Interests: Mechanisms of tumor cell death, drug resistance, antitumor drug design
Summary
Cancer research and treatment are undergoing a profound transformation thanks to advances in both molecular biology and digital technologies. On one side, the identification of novel molecular targets is reshaping therapeutic strategies, while on the other, artificial intelligence (AI) and computational approaches are emerging as powerful tools to improve diagnostics, treatment personalization, and drug development. This Special Issue aims to explore these innovative perspectives in oncology by providing a critical and comprehensive overview of recent progress.
The collection will encourage a balanced discussion of opportunities, challenges, and limitations regarding innovative approaches in oncology. Contributions are invited from researchers and clinicians across disciplines to share experimental findings, clinical applications, and critical viewpoints related to molecular mechanisms, therapeutic targeting, AI-driven technologies, and their integration into clinical practice.
By bringing together diverse insights, this Special Issue seeks to advance a more effective, responsible, and interdisciplinary approach to cancer research and treatment, bridging molecular medicine and artificial intelligence.
Keywords
Molecular Targets in Cancer Therapy, Targeted Cancer Therapy, Oncogenic Signaling Pathways, Receptor Tyrosine Kinases (RTKs), Ion channels, Tumor Suppressor Genes, Oncogenes, Epigenetic Targets in Cancer, DNA Damage Response and Repair Mechanisms, Apoptosis and Cell Cycle Regulation, Angiogenesis Inhibitors, Immune Checkpoints and Immunotherapy Targets, Tumor Microenvironment Modulation, Resistance Mechanisms to Targeted Therapy, Innovative Approaches in Oncology, Artificial Intelligence in Cancer Research, Machine Learning and Precision Medicine, Computational Tools for Cancer Diagnosis and Treatment, Translational Oncology, Clinical Applications and Ethical Challenges of AI