Special Issues
Table of Content

New Advance in Gynecologic Oncology

Submission Deadline: 31 December 2025 (closed) View: 604 Submit to Journal

Guest Editors

Prof. Dr. Kuo-Hu Chen

Email: alexgfctw@yahoo.com.tw; alexgfctw@mail.tcu.edu.tw

Affiliation: 1. School of Medicine, Tzu-Chi University, Hualien, 97004, Taiwan 

2. Department of Obstetrics and Gynecology, Taipei Tzu-Chi GeneralHospital, Hualien, 970, Taiwan 

3. Taiwan Association for Minimally Invasive Gynecology, Taoyuan, 3330, Taiwan 

4. Taiwan Association of Gynecology, Taipei, 100, Taiwan 

5. Taiwan Endometriosis Society, Taipei, 110, Taiwan

Homepage:

Research Interests: gynecologic oncology, minimally invasive gynecologic surgery,endometriosis, polycystic ovary syndrome (PCOS), high-risk pregnancy; obstetric/ gynecologic epidermiology


Summary

Dear Colleagues,

I am organizing a Special Issue titled "New advance in gynecologic oncology" in thejournal Oncology Research, a peer-reviewed journal that publishes articles and communications in the interdisciplinary area of Oncology.

Women's health is a major concern all over the world. During their lives, women may encounter the invasion of gynecologic cancers including ovarian cancer, cervical cancer, uterine corpus, and endometrial cancer, many of which maybe unexpected and have a huge percussion on the patients and their families. The gynecologic cancer per se and relevant complications significantly influence the life span and quality of the affected women. The related healthcare has been an important issue and remains to be explored.

This Special Issue solicits any original contributions and reviews that explore the nature of diseases, associated therapies, and health impacts on women and even their families in different countries and communities. Studies discussing health issues mentioned aboveare suitable for consideration in the special issue. Advances or any cutting-edge research in affected women'shealthcare are especially welcome to be published. The listed keywords suggest just a few of the many possibilities.


Keywords

gynecologic cancer, tumor marker, ovarian cancer, endometrial cancer, uterine cancer, cervical cancer, chemotherapy, target therapy, immune therapy

Published Papers


  • Open Access

    ARTICLE

    Regulation of Histone Emulsification by HPDL via LDHA/LDHB Promotes EC Cell Proliferation

    Yan Wang, Jialei Zhu, Shiyang Wei, Lijie Jin, Zhanqiu Liu, Jie Xu, Nana Yang, Xuefeng Jiang, Caizhi Wang, Lingling Wang
    Oncology Research, DOI:10.32604/or.2026.068833
    (This article belongs to the Special Issue: New Advance in Gynecologic Oncology)
    Abstract Background: The role of 4-hydroxyphenylpyruvate dioxygenase-like protein (HPDL) in endometrial cancer (EC) progression remains poorly understood, particularly its involvement in metabolic-epigenetic crosstalk via lactate-driven histone lactylation. This study aimed to investigate HPDL’s mechanistic contribution to EC pathogenesis. Methods: Stable HPDL-overexpressing and knockdown EC cell lines (HEC-1-B and AN3CA) were generated using lentiviral vectors. Functional assays (proliferation, migration, invasion), subcutaneous xenograft models in BALB/c nude mice, and molecular analyses were conducted. Lactate levels, Pan-lysine lactylation (pan-kla), histone H3K18 lactylation (H3K18la), and effects of sodium oxamate (lactate modulator) were assessed. Lactate Dehydrogenase A/Lactate Dehydrogenase B (LDHA/LDHB) knockdown,… More >

  • Open Access

    ARTICLE

    Targeting Oncogenic lncRNA KRT7-AS to Induce Ferroptosis Suppresses Ovarian Cancer Progression

    Yan Zhu, Bin Guan, Wencai Guan, Jihong Zhang, Shiyu Wang, Jimin Shi, Wei Fan, Qi Lu, Lingyun Zhang, Guoxiong Xu
    Oncology Research, DOI:10.32604/or.2026.075241
    (This article belongs to the Special Issue: New Advance in Gynecologic Oncology)
    Abstract Background: Ovarian cancer poses the greatest threat to survival among gynecologic cancers in women. Long non-coding RNAs (lncRNAs) have emerged as critical regulators in oncogenesis. The current study aimed to elucidate the function and regulatory mechanism of lncRNA KRT7-AS in ovarian cancer. Methods: The clinical significance of KRT7-AS was evaluated through bioinformatics analysis of data from public repositories. KRT7-AS expression was examined by RT-qPCR and fluorescence in situ hybridization. The function analyses were conducted using assays for cell proliferation, migration, invasion, wound healing, and colony formation. Assessment of cell cycle and apoptosis was performed using flow… More >

Share Link