Guest Editors
Dr. Keshav Raj Paudel
Email: Keshavraj.paudel@uts.edu.au
Affiliation: Faculty of Science, School of Life Sciences, University of Technology Sydney, Sydney, 2007, Australia
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Research Interests: Drug delivery, nanoformulation, lung cancer, breast cancer, pharmacology
Summary
Nanotechnology has emerged as a transformative approach in cancer therapy, enabling the targeted delivery of bioactive compounds with enhanced precision, efficacy, and safety. This special issue, Bioactive Loaded Nanoformulations Targeting Cancer, aims to showcase recent advances in the design, development, and application of nano-based delivery systems that encapsulate natural or synthetic bioactives for cancer treatment. Emphasis will be placed on nanoformulations such as liposomes, polymeric nanoparticles, dendrimers, micelles, and hybrid nanosystems that improve drug solubility, stability, tumor specificity, and reduce systemic toxicity.
The issue welcomes original research articles, reviews, and short communications that explore innovative nanoformulation strategies, characterization, in vitro and in vivo therapeutic efficacy, mechanisms of action, and translational potential. Studies focusing on overcoming multidrug resistance, enhancing tumor microenvironment modulation, and combining diagnostics with therapy (theranostics) are particularly encouraged.
By integrating bioactive compounds—such as plant-derived phytochemicals, peptides, or small molecule inhibitors—within smart nanocarriers, researchers can pave the way for next-generation cancer therapeutics. This special issue provides a platform for multidisciplinary collaboration across nanotechnology, pharmacology, oncology, and materials science to advance precision medicine in cancer care.
Keywords
nanotechnology, nanocarriers, bioactive compounds, peptides, small molecules, anti-cancer
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