Guest Editors
Dr. Mara Mădălina Mihai
Email: mara.mihai@umfcd.ro
Affiliation: 1. Department of Oncological Dermatology, Elias Emergency University Hospital, Bucharest, 011461, Romania
2. Department of Dermatology, Carol Davila University of Medicine and Pharmacy, Bucharest, 020021, Romania
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Research Interests: dermatology; microbiology; skin cancer; melanoma; nanotechnology; targeted therapy; skin healing; chronic wounds; bacterial biofilms; bacterial pathogenesis; host-microbiome interactions; antibacterial therapies

Dr. Alina-Maria Holban
Email: alina.m.holban@bio.unibuc.ro
Affiliation: 1. Department of Microbiology and Immunology, Faculty of Biology, University of Bucharest, Bucharest, 060101, Romania
2. The Research Institute of the University of Bucharest, Bucharest, 060023, Romania
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Research Interests: microbiology; immunology; new antimicrobial agents; host-pathogen signaling; infection control; antimicrobial nanomaterials; bacterial pathogenesis; virulence factors; quorum sensing; biofilms; antibacterial activity; antibiotic resistance; Staphylococcus aureus; Escherichia coli; Pseudomonas aeruginosa; microbial molecular biology; bioactive materials; nanotechnology; nanoengineering

Summary
Despite increasing public awareness and scientific interest in skin cancer risks, the incidence of both melanoma and non-melanoma skin cancers (basal cell carcinoma, squamous cell carcinoma) continues to rise rapidly. Recent research breakthroughs have provided valuable insights into the genetic and molecular landscape, as well as the role of the host-microbiome interplay in the development and treatment response of skin cancer. These discoveries have led to significant therapeutic innovations. However, resistance mechanisms remain a persistent challenge, emphasizing the need for personalized treatment approaches, combined therapies, and ongoing research to achieve lasting therapeutic outcomes. As an editorial team with expertise in clinical care and innovative therapeutics—such as drug delivery systems, nanotechnology, transdermal drug delivery systems, immunotherapy, and cold plasma—we are excited to invite you to submit your recent work to this Special Issue. Our goal is to showcase the most groundbreaking and promising developments in the management of skin cancer, from molecular targets to innovative treatments, highlighting the transformative effects of these advancements on clinical practice.
Keywords
skin cancer; Melanoma; non-melanoma skin cancer; basal cell carcinoma; squamous cell carcinoma; molecular targets; host-microbiome interplay; targeted therapy; precision medicine; drug delivery systems; nanotechnology; transdermal drug delivery; immunotherapy; cold plasma; vaccines; drug delivery systems; nanotechnology; bioactive materials