Guest Editors
Fei Tian, Associate professor, State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, China
Fei Tian is an associate professor in the Institute of Traditional Chinese Medicine at Tianjin University of Traditional Chinese Medicine (TUTCM). He received a B.E. degree (2002) in Material Science and Engineering and Ph.D. degree (2009) in Material Science from Tianjin University. After graduation, he worked at TUTCM in July 2010. He worked at the Commonwealth Scientific and Industrial Research Organisation (CSIRO) in 2015 as a visiting scholar with Professors Adrian Trinchi and Ivan Cole. His research mainly focuses on the preparation of new inorganic functional materials by pulsed laser ablation in liquid and hydrothermal methods and their application in the detection and removal of pollutants. He currently focuses on synthesizing and applying magnetic nanoparticles and carbon-based quantum dots in nanomedicine.
Adrian Trinchi, Research Scientist, Commonwealth Scientific and Industrial Research Organisation (CSIRO), Australia
Adrian Trinchi completed a Ph.D. at RMIT University, Australia, after having received BSc and BEng degrees from the University of Melbourne, Australia. Currently, he is a Principal Research Scientist and leader of the Active Materials team at the Commonwealth Scientific and Industrial Research Organisation (CSIRO) Australia. His research is focused on nano-structured materials, and he leads multi-disciplinary projects in the field of advanced and functional materials, deploying them for use in additive manufactured settings. He is particularly focused on producing functional composites for various applications, including chemical processing and upcycling of waste, embedding function within 3D printed parts, structural modification, biocompatibility and chemical sensing.
Yanxu Chang, Professor, State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, China
Prof. Yanxu Chang received a bachelor's degree in 2003, an M.S. degree from Inner Mongolia University in 2006, and a Ph.D. degree from China Pharmaceutical University in 2009. He studied as a visiting scholar at Imperial College London and the University of Michigan. He is working as a Professor at Tianjin University of Traditional Chinese Medicine. His research interests focus on drug screening from traditional Chinese Medicines (TCMs) and biosensors, green quality evaluation and methods and pharmacokinetic studies of TCMs. He has obtained over 20 projects; He has published more than 200 papers in peer-reviewed. He has applied for more than 30 invention patents. He won 9 provincial and ministerial science and technology progress awards in China. He obtained the titles of young innovation leading talents (2018) and young scientific and technological talents (2014) in Tianjin innovation talent promotion plan, Tianjin advanced individual of teachers' Ethics (2018) and Tianjin innovation expert (2021).
Xinghua Jin, Associate Professor, School of Pharmaceutical Science and Technology, Tianjin University, China
Xinghua Jin is an Associate Professor at the Pharmaceutical Science and Technology School at Tianjin University. He received his BSc from Tianjin Medical University in 2000 and his Ph.D. degree in Chemical Science and Engineering from Tianjin University in 2009. After graduation, he joined the Tianjin Key Laboratory of Modern Drug Delivery and Functional Efficiency at Tianjin University. He also served as the Director of the Analysis and Testing Center of Pharmaceutical Science and Technology School. His research focuses on the design of new functional probes for separating and detecting impurities in drugs and the development of renewable solid-phase extraction materials for separating and purifying active ingredients in traditional Chinese medicine. On the other hand, he has also been working on the development of new technologies and methods for the quality control of chemical drugs and traditional Chinese medicine. He was the recipient of several prizes and awards and the holder of relevant national patents.
Jia Hao, Associate Researcher, State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, China.
Jia Hao is an associate researcher in the Institute of Traditional Chinese Medicine at Tianjin University of Traditional Chinese Medicine (TUTCM). She received a B.S. degree (2005) in Pharmacy and Ph.D. degree (2010) in Medicinal Chemistry from China Pharmaceutical University. After graduation, she worked at TUTCM in July 2010. She is currently devoted to the discovery of natural leading candidates and to revealing their pharmacodynamic mechanism based on chemical structures.
Summary
Numerous materials were applied for the extraction, detection and removal of target toxic and/or hazardous substances efficiently in the medical field, including reversed-phase material, nonretentive supporting material, normal-phase materials and so on. In the past decades, the new sustainable materials with specific structures and functionalities for high-throughput screening and effective extraction has been paid more and more attention in the discovery of active components from herbal medicine and the process of drug development. However, herbal medicine contains a large number of complex components. The active ingredients in herbal medicine are generally flavonoids, anthraquinones, alkaloids, phenolic acids, nucleoside compounds and so on. Therefore, the extraction and determination of these bioactive compounds have great significance for future pharmacological research and clinical application of herbal medicine. Sample preparation is the key step in the analytical workflow. Matrix solid-phase dispersion (MSPD) was proposed as an efficient extraction method. It has the advantages of being time-saving, low costs, environment-friendly and no clean-up and enrichment steps compared with traditional solid-phase extraction (SPE). To achieve high extraction and clean-up performance with a short analysis time, various recyclable, renewable, and functionalized materials are developed as solid-phase sorbents.
Renewable materials have also paved their importance in pharmaceuticals and coated in biomedical devices, applied in therapeutics and diagnosis. Renewable materials also paved their importance in pharmaceuticals, including detection of hazardous compounds and drug quality control. The application of renewable materials in the current scenario provides a wide scope in the future with improvisations in chemical analysis and drug quality control. Its selectivity, sensitivity, and cost-effectiveness prove it to be a better alternative compared to other materials. This Special Issue focuses on the following renewable materials for analysis and quality control of medicine:
(i) Magnetic nanomaterials (MNMs);
(ii) Metal-organic frameworks (MOFs);
(iii) Covalent organic frameworks (COFs);
(iv) Other Renewable or recyclable materials.
Keywords
Herbal medicine; renewable materials; quality control; toxic substance; hazardous substance; chemical analysis; adsorbents; separation
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