Home / Journals / MCB / Vol.11, No.3, 2014
Table of Content
  • Open Access

    ARTICLE

    A Global Numerical Analysis of the “Central Incisor / Local Maxillary Bone” System using a Meshless Method

    S.F. Moreira, J. Belinha∗,† ,‡, L.M.J.S. Dinis∗,†, R.M. Natal Jorge∗,†
    Molecular & Cellular Biomechanics, Vol.11, No.3, pp. 151-184, 2014, DOI:10.3970/mcb.2014.011.151
    Abstract In this work the maxillary central incisor is numerically analysed with an advance discretization technique – Natural Neighbour Radial Point Interpolation Method (NNRPIM). The NNRPIM permits to organically determine the nodal connectivity, which is essential to construct the interpolation functions. The NNRPIM procedure, based uniquely in the computational nodal mesh discretizing the problem domain, allows to obtain autonomously the required integration mesh, permitting to numerically integrate the differential equations ruling the studied physical phenomenon. A numerical analysis of a tooth structure using a meshless method is presented for the first time. A two-dimensional model of the maxillary central incisor, based… More >

  • Open Access

    ARTICLE

    Mechanical Modelling of Confined Cell Migration Across Constricted-curved Micro-channels

    R. Allena*,†
    Molecular & Cellular Biomechanics, Vol.11, No.3, pp. 185-208, 2014, DOI:10.3970/mcb.2014.011.185
    Abstract Confined migration is a crucial phenomenon during embryogenesis, immune response and cancer. Here, a two-dimensional finite element model of a HeLa cell migrating across constricted–curved micro-channels is proposed. The cell is modelled as a continuum with embedded cytoplasm and nucleus, which are described by standard Maxwell viscoelastic models. The decomposition of the deformation gradient is employed to define the cyclic active strains of protrusion and contraction, which are synchronized with the adhesion forces between the cell and the substrate. The micro-channels are represented by two rigid walls and exert an additional viscous force on the cell boundaries. Five configurations have… More >

  • Open Access

    ARTICLE

    Effects of Equiaxial Strain on the Differentiation of Dental Pulp Stem Cells without Using Biochemical Reagents

    F. S. Tabatabaei, M. Jazayeri, P. Ghahari, N. Haghighipour§
    Molecular & Cellular Biomechanics, Vol.11, No.3, pp. 209-220, 2014, DOI:10.3970/mcb.2014.011.209
    Abstract During orthodontic treatments, applied mechanical forces create strain and result in tooth movement through the alveolar bone. This response to mechanical strain is a fundamental biological reaction. The present study evaluated the effect of equiaxial strain within the range of orthodontic forces on the osteogenic differentiation of human dental pulp stem cells (hDPSCs). Following isolation and culture of hDPSCs, 3rd passage cells were transferred on a silicone membrane covered with collagen. Cell adhesion to the membrane was evaluated under scanning electron microscope (SEM). Cells were divided into three groups: the first group was placed in a conventional culture medium, transferred… More >

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